The Scariest Diseases of All Time Diseases / Medical Conditions
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The Scariest Diseases of All Time

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This is a list of the scariest diseases of all time, as ranked by the Ranker Community. Everyone wants to be healthy from the minute they are born to the last breath they take, but that doesn't always happen. There are a lot of scary, debilitating things that can happen to your body along the way. A slow, wasting sickness or a something that only gives you 3 months to live? How do you rank it?

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Rank     Name Symptoms Treatments Risks
  1. 1
    Up 74
    Down 14
    Most Listed
  2. 2
    Up 71
    Down 12
    Agnosia, Labile affect, Urinary incontinence, Anosmia, Irritability, Aggression, Sundowning, Memory loss, Apraxia, Paraphasia, Hirano body, Delusional misidentification syndrome, Wandering More
    Vitamin E, Haloperidol, Sensory integration, Reminiscence therapy, Rivastigmine, Low-fat diet, Simulated presence therapy, Donezepil, Validation therapy, Memantine, Galantamine More
    Female, Old age, Diabetes mellitus, Hypertension, Down syndrome, Craniocerebral Trauma, Hypercholesterolemia, Smoking, Family history of Alzheimer's disease More
    Most Passionate
  3. 3
    Up 62
    Down 11
    Lymphadenopathy, Headache, Flu-like symptoms, Pyrexia, Fatigue, Fever
    Protease inhibitor, Reverse transcriptase inhibitor, Antiretroviral drug, Post-exposure prophylaxis More
    Vertical transmission, Unsafe sex, Sexually transmitted disease, Prostitution, Needlestick injury, Multiple sexual partners, Homosexuality, Intravenous drug use More
  4. 4
    Up 43
    Down 17
    Fatigue, Nystagmus, Erectile dysfunction, Vision loss, Dizziness, Constipation, Uveitis, Seizure, Lhermitte's sign, Urinary incontinence, Paresthesia, Pruritus, Raynaud's phenomenon, Optic atrophy, Dyspnea, Upper motor neurone lesion, Muscle weakness, Fasciculation, Internuclear ophthalmoplegia, Tremor, Sensorineural hearing loss, Memory loss, Horner's syndrome, Papillitis, Eye pain More
    Physical therapy, Occupational therapy, Interferon beta-1a, Cannabis, Corticosteroid, Modafinil, Interferon beta-1b, Medical cannabis, Natalizumab, Azathioprine, Mitoxantrone, Cyclophosphamide, Plasmapheresis, Glatiramer acetate, Antidepressants More
    Female, White, Younger age, Infection, Thyroid disease, Inflammatory bowel disease, Diabetes mellitus type 1, Family history of multiple sclerosis More
    Controversial
  5. 5
    Up 45
    Pain, Pyrexia, Diarrhea, Skin Discoloration, Vomiting, Necrosis
    Amputation, Clindamycin, Vancomycin, Debridement, Penicillin, Hyperbaric oxygen therapy, Negative pressure wound therapy More
    Chickenpox, Chemotherapy, Chronic
  6. 6
    Up 36
    Down 11
    Fatigue, Cough, Dysphagia, Cachexia, Dyspnea, Chest pain, Hemoptysis, Wheeze, Clubbing, Dysphonia More
    Adjuvant, Surgery, Chemotherapy, Radiation therapy, Brachytherapy, Photodynamic therapy, Targeted therapy, Radiofrequency ablation More
    Air pollution, Tobacco smoking, Cannabis smoking, Exposure to radon, Passive smoking, Exposure to asbestos, Personal history of lung cancer More
  7. 7
    Up 32

    Bubonic plague

    Bubo
  8. 8
    Up 32
    Delusional disorder, Choreoathetosis, Seizure, Difficulty walking, Dysphagia, Anxiety, Mental confusion, Spasticity, Depression, Fasciculation, Muscle Spasms, Slurred Speech, Chorea, Mood swing More
    Occupational therapy, Speech therapy, Valproic acid, Haloperidol, Paroxetine, Clonazepam, Risperidone, Tetrabenazine More
    Family history of Huntington's disease
  9. 9
    Up 29
    Macule, Enanthem
  10. 10
    Up 25
  11. 11
    Up 30

    Head and neck cancer

    Radiation therapy
  12. 12
    Up 33
  13. 13
    Up 27
    Down 11
    Inverted nipple, Breast lump, Nipple discharge, Nipple tenderness
    Chemotherapy, Mastectomy, Radiation therapy, Hormone therapy, Cancer immunotherapy, Neratinib More
    Caucasian race, Obesity, Radiation therapy, Tobacco smoking, Alcohol use, Sedentary lifestyle, Early onset of menstruation, Menopausal hormone therapy, Personal history of breast cancer, Delayed onset of menopause, DES use, Family history of breast cancer More
  14. 14
    Up 23
    Pyrexia, Rigor
    Antimalarial drug
  15. 15
    Up 26
    Down 12
    Controversial
  16. 16
    Up 24
    Fatigue, Drooling, Somnolence, Constipation, Postural instability, Dementia, Seborrhoeic dermatitis, Urinary incontinence, Anosmia, Dysphagia, Balance disorder, Hallucination, Dystonia, Weight loss, Gait abnormality, Akinesia, Nocturia, Intestinal pseudoobstruction, Micrographia, Tremor, Memory loss, Akathisia, Ataxia, Bradykinesia, Hypomimia More
    Physical therapy, Occupational therapy, Speech therapy, Increase fluid intake, Surgery, Anticholinergic, Amantadine, Levodopa, Deep brain stimulation, Physical exercise, Tolcapone, Transcranial magnetic stimulation, Dopamine agonist, Monoamine oxidase inhibitor More
    Male, Old age, Exposure to chemicals, Family history of Parkinson's disease, Exposure to dopamine receptor blockers, Exposure to manganese More
  17. 17
    Up 29

    Histoid leprosy

  18. 18
    Pyrexia, Hemorrhage, Headache, Constipation, Back pain, Jaundice, Nausea, Rigor More
    Palliative care
    Mosquito bite, Traveling to Africa or South America
  19. 19
    Up 21
    Fatigue, Pyrexia, Malar rash, Anxiety, Raynaud's phenomenon, Weight gain, Weight loss, Dyspnea, Arthralgia, Chest pain, Skin lesion, Depression, Dry Eye, Memory loss, Bruise More
    Non-steroidal anti-inflammatory drug, Corticosteroid, Antimalarial drug More
    African American, Female, Ultraviolet radiation exposure, Asian, Epstein-Barr virus infection More
  20. 20
    Up 22
    Cough, Dysphagia, Weight loss, Sore throat, Otalgia, Dysphonia
    Surgery, Chemotherapy, Radiation therapy, Laryngectomy, Pharyngectomy, Targeted therapy, Neck dissection More
    Human papillomavirus infection, Alcohol use, Diet lacking in fruits and vegetables, Tobacco use, Exposure to asbestos, Poor dental hygiene More
  21. 21
    Up 23
  22. 22
    Up 22
    Down 10
    Fatigue, Tachycardia, Pyrexia, Dizziness, Cardiac arrhythmia, Angina Pectoris, Syncope, Chronic cough, Dyspnea, Chest pain, Bradycardia, Cyanosis, Peripheral edema, Dry cough More
    Antibiotic, Cardiac surgery, ACE inhibitor, Aspirin, Cardioversion, Beta blocker, Statin, Fibrate More
    Male, Old age, Diabetes mellitus, Hypertension, Family history of heart disease, Obesity, Bacterial disease, Poor hygiene, Tobacco smoking, High-fat diet, Stress, High sodium diet, Sedentary lifestyle, Viral Infection, Menopause More
  23. 23
    Up 22
  24. 24
    Up 14
    Pyrexia, Diarrhea, Somnolence, Nausea, Hypovolemic Shock, Watery diarrhea, Dehydration, Cramp, Vomiting, Convulsion More
    Tetracycline, Co-trimoxazole, Erythromycin, Doxycycline, Chloramphenicol, Furazolidone More
    Achlorhydria, Malnutrition, Immunodeficiency, Eating raw or uncooked shellfish More
  25. 25
    Up 19
    Hematospermia, Sexual dysfunction, Lumbago, Hydrocele, Swollen testicle, Painless testicular lump More
    Chemotherapy, Radiation therapy, Inguinal orchiectomy, Retroperitoneal Lymph Node Dissection More
    Middle age, Orchitis, Caucasian race, HIV infection, Cryptorchidism, Inguinal hernia, Mumps, Sedentary lifestyle, Family history of testicular cancer More
  26. 26

    Lepromatous leprosy

  27. 27
    Up 14
    Flaccid paralysis
  28. 28
    Up 14
    Down 11
    Pyrexia, Headache, Dysuria, Abnormal vaginal discharge, Cervicitis, Proctitis, Penile discharge, Genital sores More
    Naproxen, Ibuprofen, Ketoprofen, Penciclovir, Acyclovir, Famciclovir
    Unsafe sex, Multiple sexual partners, Sexual contact with someone who has a sexually transmitted disease More
  29. 29

    Fournier gangrene

  30. 30

    Prostate cancer with bone metastasis

  31. 31
    Up 18
  32. 32
    Up 7
    Down 16
    Soft erections, Priapism, Sexual dysfunction
    Tadalafil, Sildenafil, Alprostadil, Vardenafil, Penile prosthesis
    Cardiovascular disease, Parkinson's disease, Old age, Personality disorder, Stroke, Diabetes mellitus, Hypertension, Alcoholism, Multiple sclerosis, Panic disorder, Alzheimer's disease, Pituitary adenoma, Obesity, Schizophrenia, Peyronie's disease, Tobacco smoking, Anxiety, Peripheral artery occlusive disease, Substance abuse, Atherosclerosis, Stress, General anxiety disorder, Depression, Prolonged bicycling, Prostatectomy, Adverse drug reaction More
  33. 33
    Up 17
    Vaginal bleeding, Dyspareunia, Pelvic pain, Increased vaginal discharge More
    Surgery, Chemotherapy, Radiation therapy, Cryosurgery, Hysterectomy, Cervical conization, Loop electrical excision procedure, Soft tissue laser surgery More
    Immunodeficiency, Sexually transmitted disease, Multiple sexual partners, Tobacco smoking, Early sexual activity More
  34. 34
  35. 35

    Pulmonary embolism

  36. 36

    Leprosy

    Epistaxis, Macule, Skin lesion, Plaque, Nodule, Nasal congestion, Thick skin More
    Dapsone, Rifampicin, Clofazimine
    Male, Mutation, Family history of Leprosy
  37. 37
    Dysphagia, Weight loss, Dysarthria, Muscle weakness, Spasticity, Fasciculation, Muscle atrophy, Muscle Spasms, Slurred Speech, Monomelic amyotrophy, Hyperreflexia More
    Physical therapy, Occupational therapy, Speech therapy, Cannabis, Riluzole, Mechanical ventilation, Transcranial magnetic stimulation, Baclofen, Tizanidine More
    Male, Old age, Exposure to chemicals, Family history of Amyotrophic lateral sclerosis More
  38. 38
    Up 12
    Fatigue, Pyrexia, Diarrhea, Headache, Constipation, Abdominal pain, Delirium, Skin Eruptions, Weight loss, Muscle weakness, Abdominal distension More
    Ciprofloxacin, Oral rehydration therapy, Ceftriaxone, Ampicillin, Chloramphenicol More
    Immunodeficiency
  39. 39
    Up 11

    Nonsyndromic deafness

  40. 40
    Up 17
    Headache, Arthralgia, Vascular Leak, Myalgia, High Fever, Retro-Orbital Pain More
    Rehydration, Fluid replacement, Observation
  41. 41
    Up 22
    Down 14
    Fatigue, Guilt, Delusion, Psychosis, Hallucination, Insomnia, Melancholia, Irritability, Agitation, Unintentional Weight Loss, Suicidal ideation, Anhedonia, Rumination More
    Bupropion, Cannabis, Selective serotonin reuptake inhibitor, Tricyclic antidepressant, Maprotiline, Lithium, Trazodone, Transcranial magnetic stimulation, Psychotherapy, Electroconvulsive therapy, Monoamine oxidase inhibitor More
    Myocardial infarction, Amyotrophic lateral sclerosis, Parkinson's disease, Trigeminal neuralgia, Stroke, Cancer, Diabetes mellitus, Alzheimer's disease, AIDS, Osteoporosis, Adolescence, Migraine, War, Chronic fatigue syndrome, Hypothyroidism, Stress, Epilepsy, Hyperthyroidism, Peptic ulcer, Dysmenorrhea, Family history of Clinical depression, Lumbago More
  42. 42

    Bacillary dysentery

  43. 43
    Up 11
    Down 11
    Pyrexia, Headache, Cough, Rigor, Muscle weakness, Epiphora, Malaise, Body ache, Itchy eyes, Red eye More
    Antiviral drug, Neuraminidase inhibitor
    Immunosuppression, Old age, Younger age, Pregnancy, Health care provider, Immunodeficiency, Influenza pandemic, Poor hygiene More
  44. 44
    Scoliosis, Difficulty walking, Gait abnormality, Gonadal atrophy, Ptosis, Dyspnea, Muscle weakness, Muscle contracture More
    Physical therapy, Occupational therapy, Orthopedic surgery, Prednisone, Carbamazepine, Dantrolene, Phenytoin, Mexiletine, Baclofen More
    Family history of muscular dystrophy
  45. 45
    Pyrexia, Bell's palsy, Meningitis, Headache, Anorexia, Sleep disorder, Paraplegia, Malaise, Erythema chronicum migrans, Memory loss, Polyneuropathy, Radiculopathy, Delayed onset muscle soreness More
    Non-steroidal anti-inflammatory drug, Tetracycline, Amoxicillin, Cefotaxime, Acetaminophen, Erythromycin, Ceftriaxone, Doxycycline, Cefuroxime, Chloramphenicol More
    Exposure to deer ticks
  46. 46
    Fatigue, Stroke, Myopathy, Pyrexia, Arthritis, Diarrhea, Hematochezia, Peripheral neuropathy, Headache, Constipation, Uveitis, Seizure, Abdominal pain, Failure to thrive, Pyoderma gangrenosum, Autoimmune hemolytic anemia, Dysphagia, Skin ulcer, Skin Eruptions, Anorexia, Nausea, Scleritis, Weight loss, Gingivitis, Arthralgia, Flatulence, Depression, Bloating, Vomiting, Erythema nodosum, Unintentional Weight Loss, Enthesitis, Anal fissure More
    Surgery, Dietary fiber, Sulfasalazine, Corticosteroid, Vitamin B Complex, Mesalazine, Diet high in omega-3-fatty acids More
    Non-steroidal anti-inflammatory drug, White, Caucasian race, Tobacco smoking, Isotretinoin, Family history of Crohn's disease More
  47. 47
    Up 13
    Tachycardia, Pyrexia, Strawberry tongue, Conjunctivitis, Skin Eruptions, Lymphadenopathy, Arthralgia, Irritability, Desquamation, Beau's lines More
    Corticosteroid, Aspirin, Anticoagulant, Coronary artery bypass surgery, Angioplasty, Intravenous immunoglobulin, Coronary stent More
    Male, Younger age, Asian
  48. 48

    Munchausen syndrome

  49. 49
    Fatigue, Pyrexia, Cough, Sweating, Dyspnea, Rigor, Chest pain, Myalgia
    Vancomycin, Rimantadine, Penicillin, Carbapenem, Amantadine, Cephalosporin, Macrolide Antibiotic, Doxycycline, Oseltamivir, Zanamivir, Quinolone, Aminoglycoside antibiotic More
    Immunosuppression, Old age, Alcoholism, Native Americans in the United States, Physical trauma, Infant, Smoking, Toddler, Exposure to chemicals, Personal history of lung infections, Hospitalization More
  50. 50
    Quadriplegia, Vision loss, Vertigo, Dizziness, Headache, Diplopia, Difficulty walking, Dysphagia, Coma, Vision disorder, Mental confusion, Aphasia, Balance disorder, Cerebral hemorrhage, Facial Paresis, Central seven, Memory loss, Hemiplegia, Ataxia More
    Physical therapy, Occupational therapy, Tissue plasminogen activator, Surgery, Intravenous therapy, Stroke rehabilitation, Thrombectomy, Carotid endarterectomy, Aspirin, Transcranial magnetic stimulation, Oxygen therapy, Angioplasty, Thrombolytic drug, Transcranial direct current stimulation More
    Male, Old age, Diabetes mellitus, Atrial fibrillation, Hypertension, Family history of heart disease, Obesity, Tobacco smoking, Hypercholesterolemia, Atherosclerosis, Stress, Alopecia, Depression, Family history of transient ischemic attack, Family history of stroke More
  51. +Add New Item

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The Scariest Diseases of All Time

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    1. dubier
      Necrotizing fasciitis at 5/19/2011 1:33 PM
      Also known as "Flesh Eating Bacteria"
    2. "Mad Cow Disease"

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