science The Scariest Diseases of All Time  

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List Rules Vote up any disease or disorder that seems like a horrible/painful thing to experience. Diseases do not have to be incurable.

You know when you have a cold and feel like you're dying? Well buck up, because your little sniffles are nothing compared to the world's scariest diseases. This list of the scariest diseases of all time, as ranked by the Ranker Community, will have you checking WebMD like a madman (or woman). Everyone wants to be healthy from the minute they are born to the last breath they take, but that doesn't always happen. There are a lot of scary, debilitating things that can happen to your body along the way. A slow, wasting sickness or a something that only gives you 3 months to live? How do you rank it? Which scary illnesses frighten you the most?

From scary skin diseases, to terrifying viruses, some of these illnesses even just have plain scary disease names to go along with their awful symptoms. Being a shut in might sound appealing after learning about these worst, horrible diseases, but that's no way to live. Still, what are the most distressing fatal diseases? Choose the fatal diseases that freak you out the most and vote them up, then talk to your doctor about how to stay healthy. 

1
+ - 751 251
Ebola virus disease is listed (or ranked) 1 on the list The Scariest Diseases of All Time

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2
+ - 656 191
Alzheimer's disease is listed (or ranked) 2 on the list The Scariest Diseases of All Time
Alzheimer's disease Apraxia, Aggression, Pathological laughing and crying

3
+ - 552 123
Necrotizing fasciitis is listed (or ranked) 3 on the list The Scariest Diseases of All Time
Necrotizing fasciitis Skin Discoloration, Pain, Necrosis

4
+ - 601 185
HIV is listed (or ranked) 4 on the list The Scariest Diseases of All Time
HIV Lymphadenopathy, Headache, Flu-like symptoms

5
+ - 437 118
Lung cancer is listed (or ranked) 5 on the list The Scariest Diseases of All Time
Lung cancer Nail clubbing, Dyspnea, Cachexia

6
+ - 365 161
Multiple sclerosis is listed (or ranked) 6 on the list The Scariest Diseases of All Time
Multiple sclerosis Optic papillitis, Horner's syndrome, Dyspnea

7
+ - 447 119
Bubonic plague is listed (or ranked) 7 on the list The Scariest Diseases of All Time

8
+ - 391 122
Smallpox is listed (or ranked) 8 on the list The Scariest Diseases of All Time
Smallpox Enanthem, Macule

9
+ - 296 125
Parkinson's disease is listed (or ranked) 9 on the list The Scariest Diseases of All Time
Parkinson's disease Drooling, Hypomimia, Tremor

10
+ - 278 108
Huntington's disease is listed (or ranked) 10 on the list The Scariest Diseases of All Time
Huntington's disease Fasciculation, Slurred Speech, Dysphagia

11
+ - 248 104
Creutzfeldt–Jakob disease is listed (or ranked) 11 on the list The Scariest Diseases of All Time

12
+ - 298 108
Breast cancer is listed (or ranked) 12 on the list The Scariest Diseases of All Time
Breast cancer Breast lump, Paget's disease of the breast, Nipple discharge

13
+ - 253 101
Head and neck cancer is listed (or ranked) 13 on the list The Scariest Diseases of All Time

14
+ - 233 76
Cancer of the larynx is listed (or ranked) 14 on the list The Scariest Diseases of All Time

15
+ - 188 85
Bovine spongiform encephalopat... is listed (or ranked) 15 on the list The Scariest Diseases of All Time

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16
+ - 200 63
Harlequin-type ichthyosis is listed (or ranked) 16 on the list The Scariest Diseases of All Time

17
+ - 206 67
Cervical cancer is listed (or ranked) 17 on the list The Scariest Diseases of All Time
Cervical cancer Pelvic pain, Vaginal bleeding, Increased vaginal discharge

18
+ - 208 112
Progeria is listed (or ranked) 18 on the list The Scariest Diseases of All Time

19
+ - 108 41
Cardiovascular disease is listed (or ranked) 19 on the list The Scariest Diseases of All Time
Cardiovascular disease Dyspnea, Dizziness, Palpitation

20
+ - 206 108
Malaria is listed (or ranked) 20 on the list The Scariest Diseases of All Time
Malaria Fever, Chills

21
+ - 181 63
Skin cancer is listed (or ranked) 21 on the list The Scariest Diseases of All Time
Skin cancer Skin ulcer, Skin lesion, Melanocytic nevus

22
+ - 202 82
Testicular cancer is listed (or ranked) 22 on the list The Scariest Diseases of All Time
Testicular cancer Swollen testicle, Lumbago, Painless testicular lump

23
+ - 222 67
Zika Virus is listed (or ranked) 23 on the list The Scariest Diseases of All Time
Zika Virus

24
+ - 128 11
Brain Cancer is listed (or ranked) 24 on the list The Scariest Diseases of All Time

25
+ - 215 120
Major depression is listed (or ranked) 25 on the list The Scariest Diseases of All Time
Major depression Boredom, Melancholia, Insomnia

26
+ - 180 60
Leprosy is listed (or ranked) 26 on the list The Scariest Diseases of All Time
Leprosy Plaque, Nasal congestion, Thick skin

27
+ - 129 55
Paranoid Schizophrenia is listed (or ranked) 27 on the list The Scariest Diseases of All Time
Paranoid Schizophrenia

28
+ - 127 58
Fatal familial insomnia is listed (or ranked) 28 on the list The Scariest Diseases of All Time

29
+ - 123 82
Poliomyelitis is listed (or ranked) 29 on the list The Scariest Diseases of All Time
Poliomyelitis Flaccid paralysis

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30
+ - 140 100
Lupus erythematosus is listed (or ranked) 30 on the list The Scariest Diseases of All Time
Lupus erythematosus Joint pain, Dyspnea, Raynaud's phenomenon

31
+ - 136 61
Lyme disease is listed (or ranked) 31 on the list The Scariest Diseases of All Time
Lyme disease Bell's palsy, Radiculopathy, Malaise

32
+ - 118 69
Proteus syndrome is listed (or ranked) 32 on the list The Scariest Diseases of All Time

33
+ - 129 32
Muscular dystrophy is listed (or ranked) 33 on the list The Scariest Diseases of All Time
Muscular dystrophy Dyspnea, Gait abnormality, Scoliosis

34
+ - 140 74
Histoid leprosy is listed (or ranked) 34 on the list The Scariest Diseases of All Time

35
+ - 140 95
Genital herpes is listed (or ranked) 35 on the list The Scariest Diseases of All Time
Genital herpes Proctitis, Dysuria, Fever

36
+ - 114 67
Dengue fever is listed (or ranked) 36 on the list The Scariest Diseases of All Time
Dengue fever Pain behind the eyes, Joint pain, Vascular Leak

37
+ - 107 35
Prostate cancer with bone meta... is listed (or ranked) 37 on the list The Scariest Diseases of All Time

38
+ - 100 55
Typhoid fever is listed (or ranked) 38 on the list The Scariest Diseases of All Time
Typhoid fever Fatigue, Abdominal pain, Fever

39
+ - 101 43
Fibrodysplasia ossificans prog... is listed (or ranked) 39 on the list The Scariest Diseases of All Time

40
+ - 148 44
Rabies is listed (or ranked) 40 on the list The Scariest Diseases of All Time

41
+ - 107 52
Amyotrophic lateral sclerosis is listed (or ranked) 41 on the list The Scariest Diseases of All Time
Amyotrophic lateral sclerosis Hyperreflexia, Fasciculation, Slurred Speech

42
+ - 86 40
Pulmonary embolism is listed (or ranked) 42 on the list The Scariest Diseases of All Time
Pulmonary embolism Dyspnea, Collapse, Hemoptysis

43
+ - 92 49
Crohn's disease is listed (or ranked) 43 on the list The Scariest Diseases of All Time
Crohn's disease Autoimmune hemolytic anemia, Scleritis, Fever

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44
+ - 73 60
Kawasaki disease is listed (or ranked) 44 on the list The Scariest Diseases of All Time
Kawasaki disease Joint pain, Lymphadenopathy, Strawberry tongue

45
+ - 70 55
Hantavirus Infection is listed (or ranked) 45 on the list The Scariest Diseases of All Time

46
+ - 76 45
Lepromatous leprosy is listed (or ranked) 46 on the list The Scariest Diseases of All Time

47
+ - 67 14
Ovarian cancer is listed (or ranked) 47 on the list The Scariest Diseases of All Time
Ovarian cancer Pelvic pain, Dyspnea, Bloating

48
+ - 90 106
Influenza is listed (or ranked) 48 on the list The Scariest Diseases of All Time
Influenza Watery eyes, Red eye, Fever

49
+ - 65 55
Dissociative identity disorder is listed (or ranked) 49 on the list The Scariest Diseases of All Time

50
+ - 42 13
Primary Amebic Meningoencephal... is listed (or ranked) 50 on the list The Scariest Diseases of All Time
Primary Amebic Meningoencephalitis