Total Nerd The Best Villains Deadpool Has Ever Faced  

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List Rules Vote up all your favorite villains that you love to see Deadpool go at it with! No heroes!

The Merc with a Mouth, or Deadpool, was created in 1991 by writer Fabian Nicieza and comic illustrator Rob Liefeld. Though Deadpool walks the line of being a villain himself, he's also fought some of the nastiest evil guys around to help save the planet and humankind... when the price is right, anyway. This anti-hero may not always feel the urge to save the day, he still displays an impressive rogue gallery, and we're here to show it to you.
 
We've listed all of Deadpool's greatest enemies on here. Who do you think is the best villain this comic book hero's ever encountered? Do you enjoy the rivalry between Deadpool and Madcap, or do you hold Death in a special place in your heart? 
Make sure to vote up all your favorite Deadpool villains, and vote down the ones you despise. Don't see the villain you love to hate on this list? Be sure to add them!
list ordered by

1
+ - 1,199 185
Carnage is listed (or ranked) 1 on the list The Best Villains Deadpool Has Ever Faced

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2
+ - 874 244
Deathstroke is listed (or ranked) 2 on the list The Best Villains Deadpool Has Ever Faced

3
+ - 654 200
Evil Deadpool is listed (or ranked) 3 on the list The Best Villains Deadpool Has Ever Faced
Evil Deadpool

4
+ - 590 183
Apocalypse is listed (or ranked) 4 on the list The Best Villains Deadpool Has Ever Faced

5
+ - 652 232
Taskmaster is listed (or ranked) 5 on the list The Best Villains Deadpool Has Ever Faced

6
+ - 461 188
Death is listed (or ranked) 6 on the list The Best Villains Deadpool Has Ever Faced

7
+ - 409 177
Red Hulk is listed (or ranked) 7 on the list The Best Villains Deadpool Has Ever Faced

8
+ - 398 183
Magneto is listed (or ranked) 8 on the list The Best Villains Deadpool Has Ever Faced

9
+ - 360 174
Loki is listed (or ranked) 9 on the list The Best Villains Deadpool Has Ever Faced

10
+ - 363 186
Mister Sinister is listed (or ranked) 10 on the list The Best Villains Deadpool Has Ever Faced

11
+ - 334 167
Juggernaut is listed (or ranked) 11 on the list The Best Villains Deadpool Has Ever Faced

12
+ - 317 161
Doctor Doom is listed (or ranked) 12 on the list The Best Villains Deadpool Has Ever Faced

13
+ - 326 172
Sabretooth is listed (or ranked) 13 on the list The Best Villains Deadpool Has Ever Faced

14
+ - 286 204
BULLSEYE is listed (or ranked) 14 on the list The Best Villains Deadpool Has Ever Faced

15
+ - 244 180
Crossbones is listed (or ranked) 15 on the list The Best Villains Deadpool Has Ever Faced

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16
+ - 232 189
Flash Thompson is listed (or ranked) 16 on the list The Best Villains Deadpool Has Ever Faced

17
+ - 117 67
Black Panther is listed (or ranked) 17 on the list The Best Villains Deadpool Has Ever Faced
Black Panther

18
+ - 202 180
Sentinel is listed (or ranked) 18 on the list The Best Villains Deadpool Has Ever Faced

19
+ - 201 182
Daken is listed (or ranked) 19 on the list The Best Villains Deadpool Has Ever Faced

20
+ - 194 174
Green Goblin is listed (or ranked) 20 on the list The Best Villains Deadpool Has Ever Faced
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21
+ - 178 177
Typhoid Mary is listed (or ranked) 21 on the list The Best Villains Deadpool Has Ever Faced

22
+ - 159 189
Vertigo is listed (or ranked) 22 on the list The Best Villains Deadpool Has Ever Faced

23
+ - 150 177
Black Mamba is listed (or ranked) 23 on the list The Best Villains Deadpool Has Ever Faced

24
+ - 152 187
Dr. Otto Octavius is listed (or ranked) 24 on the list The Best Villains Deadpool Has Ever Faced

25
+ - 30 15
Ajax is listed (or ranked) 25 on the list The Best Villains Deadpool Has Ever Faced

26
+ - 136 179
Blob is listed (or ranked) 26 on the list The Best Villains Deadpool Has Ever Faced

27
+ - 140 192
T-Ray is listed (or ranked) 27 on the list The Best Villains Deadpool Has Ever Faced

28
+ - 128 175
Madcap is listed (or ranked) 28 on the list The Best Villains Deadpool Has Ever Faced

29
+ - 124 171
Tombstone is listed (or ranked) 29 on the list The Best Villains Deadpool Has Ever Faced

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30
+ - 65 98
Man-Thing is listed (or ranked) 30 on the list The Best Villains Deadpool Has Ever Faced

31
+ - 94 149
Beyonder is listed (or ranked) 31 on the list The Best Villains Deadpool Has Ever Faced

32
+ - 87 138
Shriek is listed (or ranked) 32 on the list The Best Villains Deadpool Has Ever Faced

33
+ - 102 167
Sauron is listed (or ranked) 33 on the list The Best Villains Deadpool Has Ever Faced

34
+ - 6 6
Slayback is listed (or ranked) 34 on the list The Best Villains Deadpool Has Ever Faced
Slayback

35
+ - 98 170
Black Tom Cassidy is listed (or ranked) 35 on the list The Best Villains Deadpool Has Ever Faced

36
+ - 93 163
Ghost is listed (or ranked) 36 on the list The Best Villains Deadpool Has Ever Faced

37
+ - 92 166
Mister X is listed (or ranked) 37 on the list The Best Villains Deadpool Has Ever Faced

38
+ - 79 149
Arcade is listed (or ranked) 38 on the list The Best Villains Deadpool Has Ever Faced

39
+ - 74 146
Doctor Bong is listed (or ranked) 39 on the list The Best Villains Deadpool Has Ever Faced

40
+ - 77 154
Blockbuster is listed (or ranked) 40 on the list The Best Villains Deadpool Has Ever Faced

41
+ - 70 143
Tiger Shark is listed (or ranked) 41 on the list The Best Villains Deadpool Has Ever Faced

42
+ - 72 153
Arclight is listed (or ranked) 42 on the list The Best Villains Deadpool Has Ever Faced

43
+ - 66 146
Headsman is listed (or ranked) 43 on the list The Best Villains Deadpool Has Ever Faced

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44
+ - 61 139
Batroc the Leaper is listed (or ranked) 44 on the list The Best Villains Deadpool Has Ever Faced

45
+ - 62 141
Constrictor is listed (or ranked) 45 on the list The Best Villains Deadpool Has Ever Faced

46
+ - 62 141
Bulldozer is listed (or ranked) 46 on the list The Best Villains Deadpool Has Ever Faced

47
+ - 64 145
Black Talon is listed (or ranked) 47 on the list The Best Villains Deadpool Has Ever Faced

48
+ - 56 134
Wrecker is listed (or ranked) 48 on the list The Best Villains Deadpool Has Ever Faced

49
+ - 55 134
Paladin is listed (or ranked) 49 on the list The Best Villains Deadpool Has Ever Faced

50
+ - 56 138
Piledriver is listed (or ranked) 50 on the list The Best Villains Deadpool Has Ever Faced