fictional characters The Best Villains Deadpool Has Ever Faced

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List Rules Vote up all your favorite villains that you love to see Deadpool go at it with! No heroes!

The Merc with a Mouth, or Deadpool, was created in 1991 by writer Fabian Nicieza and comic illustrator Rob Liefeld. Though Deadpool walks the line of being a villain himself, he's also fought some of the nastiest evil guys around to help save the planet and humankind... when the price is right, anyway. This anti-hero may not always feel the urge to save the day, he still displays an impressive rogue gallery, and we're here to show it to you.
 
We've listed all of Deadpool's greatest enemies on here. Who do you think is the best villain this comic book hero's ever encountered? Do you enjoy the rivalry between Deadpool and Madcap, or do you hold Death in a special place in your heart? 
Make sure to vote up all your favorite Deadpool villains, and vote down the ones you despise. Don't see the villain you love to hate on this list? Be sure to add them!

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Carnage is listed (or ranked) 1 on the list The Best Villains Deadpool Has Ever Faced

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Deathstroke is listed (or ranked) 2 on the list The Best Villains Deadpool Has Ever Faced

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Evil Deadpool is listed (or ranked) 3 on the list The Best Villains Deadpool Has Ever Faced
Evil Deadpool

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Apocalypse is listed (or ranked) 4 on the list The Best Villains Deadpool Has Ever Faced

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Taskmaster is listed (or ranked) 5 on the list The Best Villains Deadpool Has Ever Faced

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Death is listed (or ranked) 6 on the list The Best Villains Deadpool Has Ever Faced

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Red Hulk is listed (or ranked) 7 on the list The Best Villains Deadpool Has Ever Faced

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Magneto is listed (or ranked) 8 on the list The Best Villains Deadpool Has Ever Faced

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Loki is listed (or ranked) 9 on the list The Best Villains Deadpool Has Ever Faced

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Mister Sinister is listed (or ranked) 10 on the list The Best Villains Deadpool Has Ever Faced

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Juggernaut is listed (or ranked) 11 on the list The Best Villains Deadpool Has Ever Faced

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Sabretooth is listed (or ranked) 12 on the list The Best Villains Deadpool Has Ever Faced

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Doctor Doom is listed (or ranked) 13 on the list The Best Villains Deadpool Has Ever Faced

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BULLSEYE is listed (or ranked) 14 on the list The Best Villains Deadpool Has Ever Faced

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Crossbones is listed (or ranked) 15 on the list The Best Villains Deadpool Has Ever Faced

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Flash Thompson is listed (or ranked) 16 on the list The Best Villains Deadpool Has Ever Faced

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Black Panther is listed (or ranked) 17 on the list The Best Villains Deadpool Has Ever Faced
Black Panther

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Sentinel is listed (or ranked) 18 on the list The Best Villains Deadpool Has Ever Faced

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Daken is listed (or ranked) 19 on the list The Best Villains Deadpool Has Ever Faced

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Green Goblin is listed (or ranked) 20 on the list The Best Villains Deadpool Has Ever Faced
Green Goblin Marvel 1602

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Typhoid Mary is listed (or ranked) 21 on the list The Best Villains Deadpool Has Ever Faced

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Vertigo is listed (or ranked) 22 on the list The Best Villains Deadpool Has Ever Faced

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Black Mamba is listed (or ranked) 23 on the list The Best Villains Deadpool Has Ever Faced

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Dr. Otto Octavius is listed (or ranked) 24 on the list The Best Villains Deadpool Has Ever Faced

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Blob is listed (or ranked) 25 on the list The Best Villains Deadpool Has Ever Faced

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T-Ray is listed (or ranked) 26 on the list The Best Villains Deadpool Has Ever Faced

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Tombstone is listed (or ranked) 27 on the list The Best Villains Deadpool Has Ever Faced

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Madcap is listed (or ranked) 28 on the list The Best Villains Deadpool Has Ever Faced

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Man-Thing is listed (or ranked) 29 on the list The Best Villains Deadpool Has Ever Faced

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Ajax is listed (or ranked) 30 on the list The Best Villains Deadpool Has Ever Faced

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Beyonder is listed (or ranked) 31 on the list The Best Villains Deadpool Has Ever Faced

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Shriek is listed (or ranked) 32 on the list The Best Villains Deadpool Has Ever Faced

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Sauron is listed (or ranked) 33 on the list The Best Villains Deadpool Has Ever Faced

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Slayback is listed (or ranked) 34 on the list The Best Villains Deadpool Has Ever Faced
Slayback

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Mister X is listed (or ranked) 35 on the list The Best Villains Deadpool Has Ever Faced

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Ghost is listed (or ranked) 36 on the list The Best Villains Deadpool Has Ever Faced

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Black Tom Cassidy is listed (or ranked) 37 on the list The Best Villains Deadpool Has Ever Faced

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Arcade is listed (or ranked) 38 on the list The Best Villains Deadpool Has Ever Faced

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Doctor Bong is listed (or ranked) 39 on the list The Best Villains Deadpool Has Ever Faced

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Blockbuster is listed (or ranked) 40 on the list The Best Villains Deadpool Has Ever Faced

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Arclight is listed (or ranked) 41 on the list The Best Villains Deadpool Has Ever Faced

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Tiger Shark is listed (or ranked) 42 on the list The Best Villains Deadpool Has Ever Faced

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Batroc the Leaper is listed (or ranked) 43 on the list The Best Villains Deadpool Has Ever Faced

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Constrictor is listed (or ranked) 44 on the list The Best Villains Deadpool Has Ever Faced

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Bulldozer is listed (or ranked) 45 on the list The Best Villains Deadpool Has Ever Faced

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Black Talon is listed (or ranked) 46 on the list The Best Villains Deadpool Has Ever Faced

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Headsman is listed (or ranked) 47 on the list The Best Villains Deadpool Has Ever Faced

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Wrecker is listed (or ranked) 48 on the list The Best Villains Deadpool Has Ever Faced

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Paladin is listed (or ranked) 49 on the list The Best Villains Deadpool Has Ever Faced

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Piledriver is listed (or ranked) 50 on the list The Best Villains Deadpool Has Ever Faced