Sometimes, the experiences they have are transcendent, like Lindsey Lohan seeing herself reborn, or Brian Wilson's legendary audio hallucinations that helped him craft the music of the Beach Boys. Sometimes, they can be terribly destructive. And then there are the trips that are just too weird to put into words, like Nic Cage thinking his cat was his brother, or Jack Nicholson seeing the face of God.
Here are some of the strangest things celebrities have seen while tripping.
The legendary actor did a huge amount of psychedelics during the '60s and early '70s, and claims he saw nothing less than the Almighty while on drugs. A Nicholson biography quotes the actor as saying he "believed he saw the face of God" the first time he took LSD. Nicholson took everything from acid to large amounts of cocaine, bust started dialing back his use in the '80s.
Birthplace: Neptune City, New Jersey, United States of America
Credits: The Shining, The Departed, As Good as It Gets, Chinatown
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The actor dropped acid to prepare for a role in the film The Necessary Death of Charlie Countryman. Naturally, he live tweeted the experience, and among his observations about mayonnaise, Indiana Jones, and wearing multiple watches; LaBeouf had a vivid hallucination of fire coming out of a security guard's head at Walgreens.
Birthplace: Los Angeles, California, United States of America
Credits: Transformers, Transformers: Dark of the Moon, Transformers: Revenge of the Fallen, Fury
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The actress told a story on Jimmy Kimmel's show about struggling to find something that would help her sleep, and trying a cannabis tincture. Rather than sleep, McAdams claimed she had a bad trip, hallucinating opera singing for hours.
Birthplace: London, Canada
Credits: Midnight in Paris, Sherlock Holmes, Mean Girls, Spotlight
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Apparently, Miley Cyrus really likes weed. And she likes weed laced with psychedelics even more, because they make her see cool stuff. As she described to Rolling Stone, "One time I smoked a joint with peyote in it, and I saw a wolf howling at the moon."
Birthplace: Nashville, Tennessee, United States of America
Credits: Bolt, Justin Bieber: Never Say Never, The Last Song, Hannah Montana: The Movie
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Cage told a story on David Letterman about a time before he was famous when he did mushrooms with his cat. The cat apparently had a bad habit of getting into the actor's drugs. So, as Cage says, he took some himself, and he and the cat laid across from each other for hours, with Cage hallucinating that the cat was his brother.
Birthplace: Long Beach, California, United States of America
Credits: Leaving Las Vegas, National Treasure, Moonstruck, Kick-Ass
#91 on The Coolest Actors Eversee more on Nicolas Cage
For her Netflix series Chelsea Does, the comic sampled ayahuasca, the medicinal brew that's a new favorite of upper-class and celebrity trippers. Handler vomited in a bucket, chanted, and eventually had powerful visions of she and her sister laughing together on a kayak.
Birthplace: Livingston, New Jersey, United States of America
Credits: The Tonight Show with Jay Leno, Chelsea Lately, MTV Video Music Awards 2010, After Lately
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The troubled actress is a devotee of ayahuasca, saying an experience with the drug led her to hallucinate that she died and was born again.
Birthplace: New York City, New York, United States of America
Credits: Herbie Fully Loaded, Mean Girls, The Parent Trap, Freaky Friday
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Jackass star Steve-O was a heavy drug user until 2008, when he got sober and went to rehab. He claims that a turning point in the decision was his heavy psychedelic use, which led him to hallucinate voices that were "telling him he was going to have to answer for the times he had done to harm people."
Birthplace: England, London
Credits: Jackass: The Movie, Jackass Number Two, Jackass 3D, Jackass 3.5see more on Steve-O