Hello :) this is a list about female characters you better not mess around with. This is my personal list of the most badass girls in anime ever (at least for the animes I have seen). I will add some characters as soon as I saw more animes containing female badass characters.
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Fullmetal Alchemist: Brotherhood
Appears In: Fullmetal Alchemist: Brotherhood, Fullmetal Alchemist, Fullmetal Alchemist the Movie: Conqueror of Shamballasee more on Riza Hawkeye
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Fate/Stay Night: Unlimited Blade Works
Appears In: Fate/Zero, Fate/Stay Night: Unlimited Blade Works, Fate/Zerosee more on Saber