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Popular Opinion The Scariest Diseases of All Time  

Ranker Community
Originally by Ranker Community
19.6k votes 2.2k voters 197.8k views

List Rules Vote up any disease or disorder that seems like a horrible/painful thing to experience. Diseases do not have to be incurable.

You know when you have a cold and feel like you're dying? Well buck up, because your little sniffles are nothing compared to the world's scariest diseases. This list of the scariest diseases of all time, as ranked by the Ranker Community, will have you checking WebMD like a madman (or woman). Everyone wants to be healthy from the minute they are born to the last breath they take, but that doesn't always happen. There are a lot of scary, debilitating things that can happen to your body along the way. A slow, wasting sickness or a something that only gives you 3 months to live? How do you rank it? Which scary illnesses frighten you the most?

From scary skin diseases, to terrifying viruses, some of these illnesses even just have plain scary disease names to go along with their awful symptoms. Being a shut in might sound appealing after learning about these worst, horrible diseases, but that's no way to live. Still, what are the most distressing fatal diseases? Choose the fatal diseases that freak you out the most and vote them up, then talk to your doctor about how to stay healthy. 
list ordered by

1
855 309
Ebola is listed (or ranked) 1 on the list The Scariest Diseases of All Time

2
764 221
Alzheimer's disease is listed (or ranked) 2 on the list The Scariest Diseases of All Time
Apraxia, Aggression, Pathological laughing and crying

3
643 146
Necrotizing fasciitis is listed (or ranked) 3 on the list The Scariest Diseases of All Time
Skin Discoloration, Pain, Necrosis

4
664 222
HIV is listed (or ranked) 4 on the list The Scariest Diseases of All Time
Lymphadenopathy, Headache, Flu-like symptoms

5
501 135
Lung cancer is listed (or ranked) 5 on the list The Scariest Diseases of All Time
Nail clubbing, Dyspnea, Cachexia

6
526 133
Bubonic plague is listed (or ranked) 6 on the list The Scariest Diseases of All Time

7
415 184
Multiple sclerosis is listed (or ranked) 7 on the list The Scariest Diseases of All Time
Optic papillitis, Horner's syndrome, Dyspnea

8
445 149
Smallpox is listed (or ranked) 8 on the list The Scariest Diseases of All Time
Enanthem, Macule

9
346 145
Parkinson's disease is listed (or ranked) 9 on the list The Scariest Diseases of All Time
Drooling, Hypomimia, Tremor

10
322 129
Huntington's disease is listed (or ranked) 10 on the list The Scariest Diseases of All Time
Fasciculation, Slurred Speech, Dysphagia

11
290 117
Creutzfeldt–Jakob disease is listed (or ranked) 11 on the list The Scariest Diseases of All Time

12
338 121
Breast cancer is listed (or ranked) 12 on the list The Scariest Diseases of All Time
Breast lump, Paget's disease of the breast, Nipple discharge

13
295 110
Head and neck cancer is listed (or ranked) 13 on the list The Scariest Diseases of All Time

14
268 81
Cancer of the larynx is listed (or ranked) 14 on the list The Scariest Diseases of All Time

15
227 94
Bovine spongiform encephalopat... is listed (or ranked) 15 on the list The Scariest Diseases of All Time

16
244 72
Harlequin-type ichthyosis is listed (or ranked) 16 on the list The Scariest Diseases of All Time

17
236 124
Progeria is listed (or ranked) 17 on the list The Scariest Diseases of All Time

18
235 117
Malaria is listed (or ranked) 18 on the list The Scariest Diseases of All Time
Fever, Chills

19
231 78
Cervical cancer is listed (or ranked) 19 on the list The Scariest Diseases of All Time
Pelvic pain, Vaginal bleeding, Increased vaginal discharge

20
128 53
Cardiovascular disease is listed (or ranked) 20 on the list The Scariest Diseases of All Time
Dyspnea, Dizziness, Palpitation

21
163 13
Brain Cancer is listed (or ranked) 21 on the list The Scariest Diseases of All Time
possumprincess added

22
201 75
Skin cancer is listed (or ranked) 22 on the list The Scariest Diseases of All Time
Skin ulcer, Skin lesion, Melanocytic nevus

23
223 95
Testicular cancer is listed (or ranked) 23 on the list The Scariest Diseases of All Time
Swollen testicle, Lumbago, Painless testicular lump

24
259 133
Major depression is listed (or ranked) 24 on the list The Scariest Diseases of All Time
Boredom, Melancholia, Insomnia

25
245 81
Zika Virus is listed (or ranked) 25 on the list The Scariest Diseases of All Time
ravi2 added Zika Virus

26
164 64
Fatal familial insomnia is listed (or ranked) 26 on the list The Scariest Diseases of All Time
Seera Sea added

27
160 63
Paranoid Schizophrenia is listed (or ranked) 27 on the list The Scariest Diseases of All Time
klclyde added Paranoid Schizophrenia

28
145 88
Poliomyelitis is listed (or ranked) 28 on the list The Scariest Diseases of All Time
Flaccid paralysis

29
211 68
Leprosy is listed (or ranked) 29 on the list The Scariest Diseases of All Time
Plaque, Nasal congestion, Thick skin

30
160 109
Lupus erythematosus is listed (or ranked) 30 on the list The Scariest Diseases of All Time
Joint pain, Dyspnea, Raynaud's phenomenon

31
135 74
Proteus syndrome is listed (or ranked) 31 on the list The Scariest Diseases of All Time

32
156 68
Lyme disease is listed (or ranked) 32 on the list The Scariest Diseases of All Time
Bell's palsy, Radiculopathy, Malaise

33
154 80
Histoid leprosy is listed (or ranked) 33 on the list The Scariest Diseases of All Time

34
143 39
Muscular dystrophy is listed (or ranked) 34 on the list The Scariest Diseases of All Time
Dyspnea, Gait abnormality, Scoliosis

35
130 74
Dengue fever is listed (or ranked) 35 on the list The Scariest Diseases of All Time
Pain behind the eyes, Joint pain, Vascular Leak

36
154 107
Genital herpes is listed (or ranked) 36 on the list The Scariest Diseases of All Time
Proctitis, Dysuria, Fever

37
130 49
Fibrodysplasia ossificans prog... is listed (or ranked) 37 on the list The Scariest Diseases of All Time

38
189 50
Rabies is listed (or ranked) 38 on the list The Scariest Diseases of All Time
BrandiWolf added

39
113 60
Typhoid fever is listed (or ranked) 39 on the list The Scariest Diseases of All Time
Fatigue, Abdominal pain, Fever

40
121 40
Prostate cancer with bone meta... is listed (or ranked) 40 on the list The Scariest Diseases of All Time

41
124 56
Amyotrophic lateral sclerosis is listed (or ranked) 41 on the list The Scariest Diseases of All Time
Hyperreflexia, Fasciculation, Slurred Speech

42
101 42
Pulmonary embolism is listed (or ranked) 42 on the list The Scariest Diseases of All Time
Dyspnea, Collapse, Hemoptysis

43
103 55
Crohn's disease is listed (or ranked) 43 on the list The Scariest Diseases of All Time
Autoimmune hemolytic anemia, Scleritis, Fever

44
79 61
Hantavirus Infection is listed (or ranked) 44 on the list The Scariest Diseases of All Time

45
79 67
Kawasaki disease is listed (or ranked) 45 on the list The Scariest Diseases of All Time
Joint pain, Lymphadenopathy, Strawberry tongue

46
78 18
Ovarian cancer is listed (or ranked) 46 on the list The Scariest Diseases of All Time
possumprincess added Pelvic pain, Dyspnea, Bloating

47
83 51
Lepromatous leprosy is listed (or ranked) 47 on the list The Scariest Diseases of All Time

48
99 119
Influenza is listed (or ranked) 48 on the list The Scariest Diseases of All Time
Watery eyes, Red eye, Fever

49
74 62
Dissociative identity disorder is listed (or ranked) 49 on the list The Scariest Diseases of All Time

50
52 16
Primary Amebic Meningoencephal... is listed (or ranked) 50 on the list The Scariest Diseases of All Time
DevonteJohnsen added Primary Amebic Meningoencephalitis