Popular Opinion The Scariest Diseases of All Time  

Ranker Community
Originally by Ranker Community
19.3k votes 2.2k voters 196.6k views 80 items

List Rules Vote up any disease or disorder that seems like a horrible/painful thing to experience. Diseases do not have to be incurable.

You know when you have a cold and feel like you're dying? Well buck up, because your little sniffles are nothing compared to the world's scariest diseases. This list of the scariest diseases of all time, as ranked by the Ranker Community, will have you checking WebMD like a madman (or woman). Everyone wants to be healthy from the minute they are born to the last breath they take, but that doesn't always happen. There are a lot of scary, debilitating things that can happen to your body along the way. A slow, wasting sickness or a something that only gives you 3 months to live? How do you rank it? Which scary illnesses frighten you the most?

From scary skin diseases, to terrifying viruses, some of these illnesses even just have plain scary disease names to go along with their awful symptoms. Being a shut in might sound appealing after learning about these worst, horrible diseases, but that's no way to live. Still, what are the most distressing fatal diseases? Choose the fatal diseases that freak you out the most and vote them up, then talk to your doctor about how to stay healthy. 

1
839 302
Ebola is listed (or ranked) 1 on the list The Scariest Diseases of All Time

2
746 219
Alzheimer's disease is listed (or ranked) 2 on the list The Scariest Diseases of All Time
Alzheimer's disease Apraxia, Aggression, Pathological laughing and crying

3
627 144
Necrotizing fasciitis is listed (or ranked) 3 on the list The Scariest Diseases of All Time
Necrotizing fasciitis Skin Discoloration, Pain, Necrosis

4
656 217
HIV is listed (or ranked) 4 on the list The Scariest Diseases of All Time
HIV Lymphadenopathy, Headache, Flu-like symptoms

5
495 131
Lung cancer is listed (or ranked) 5 on the list The Scariest Diseases of All Time
Lung cancer Nail clubbing, Dyspnea, Cachexia

6
517 131
Bubonic plague is listed (or ranked) 6 on the list The Scariest Diseases of All Time

7
411 180
Multiple sclerosis is listed (or ranked) 7 on the list The Scariest Diseases of All Time
Multiple sclerosis Optic papillitis, Horner's syndrome, Dyspnea

8
441 143
Smallpox is listed (or ranked) 8 on the list The Scariest Diseases of All Time
Smallpox Enanthem, Macule

9
339 143
Parkinson's disease is listed (or ranked) 9 on the list The Scariest Diseases of All Time
Parkinson's disease Drooling, Hypomimia, Tremor

10
318 125
Huntington's disease is listed (or ranked) 10 on the list The Scariest Diseases of All Time
Huntington's disease Fasciculation, Slurred Speech, Dysphagia

11
285 115
Creutzfeldt–Jakob disease is listed (or ranked) 11 on the list The Scariest Diseases of All Time

12
332 119
Breast cancer is listed (or ranked) 12 on the list The Scariest Diseases of All Time
Breast cancer Breast lump, Paget's disease of the breast, Nipple discharge

13
293 107
Head and neck cancer is listed (or ranked) 13 on the list The Scariest Diseases of All Time

14
265 79
Cancer of the larynx is listed (or ranked) 14 on the list The Scariest Diseases of All Time

15
224 92
Bovine spongiform encephalopat... is listed (or ranked) 15 on the list The Scariest Diseases of All Time

16
240 70
Harlequin-type ichthyosis is listed (or ranked) 16 on the list The Scariest Diseases of All Time

17
232 121
Progeria is listed (or ranked) 17 on the list The Scariest Diseases of All Time

18
231 116
Malaria is listed (or ranked) 18 on the list The Scariest Diseases of All Time
Malaria Fever, Chills

19
226 77
Cervical cancer is listed (or ranked) 19 on the list The Scariest Diseases of All Time
Cervical cancer Pelvic pain, Vaginal bleeding, Increased vaginal discharge

20
124 51
Cardiovascular disease is listed (or ranked) 20 on the list The Scariest Diseases of All Time
Cardiovascular disease Dyspnea, Dizziness, Palpitation

21
159 12
Brain Cancer is listed (or ranked) 21 on the list The Scariest Diseases of All Time
possumprincess added Brain Cancer

22
221 92
Testicular cancer is listed (or ranked) 22 on the list The Scariest Diseases of All Time
Testicular cancer Swollen testicle, Lumbago, Painless testicular lump

23
199 73
Skin cancer is listed (or ranked) 23 on the list The Scariest Diseases of All Time
Skin cancer Skin ulcer, Skin lesion, Melanocytic nevus

24
255 132
Major depression is listed (or ranked) 24 on the list The Scariest Diseases of All Time
Major depression Boredom, Melancholia, Insomnia

25
243 79
Zika Virus is listed (or ranked) 25 on the list The Scariest Diseases of All Time
ravi2 added Zika Virus

26
162 62
Fatal familial insomnia is listed (or ranked) 26 on the list The Scariest Diseases of All Time
Seera Sea added Fatal familial insomnia

27
157 62
Paranoid Schizophrenia is listed (or ranked) 27 on the list The Scariest Diseases of All Time
klclyde added Paranoid Schizophrenia

28
142 86
Poliomyelitis is listed (or ranked) 28 on the list The Scariest Diseases of All Time
Poliomyelitis Flaccid paralysis

29
208 66
Leprosy is listed (or ranked) 29 on the list The Scariest Diseases of All Time
Leprosy Plaque, Nasal congestion, Thick skin

30
157 106
Lupus erythematosus is listed (or ranked) 30 on the list The Scariest Diseases of All Time
Lupus erythematosus Joint pain, Dyspnea, Raynaud's phenomenon

31
133 72
Proteus syndrome is listed (or ranked) 31 on the list The Scariest Diseases of All Time

32
153 67
Lyme disease is listed (or ranked) 32 on the list The Scariest Diseases of All Time
Lyme disease Bell's palsy, Radiculopathy, Malaise

33
152 78
Histoid leprosy is listed (or ranked) 33 on the list The Scariest Diseases of All Time

34
142 36
Muscular dystrophy is listed (or ranked) 34 on the list The Scariest Diseases of All Time
Muscular dystrophy Dyspnea, Gait abnormality, Scoliosis

35
127 72
Dengue fever is listed (or ranked) 35 on the list The Scariest Diseases of All Time
Dengue fever Pain behind the eyes, Joint pain, Vascular Leak

36
152 105
Genital herpes is listed (or ranked) 36 on the list The Scariest Diseases of All Time
Genital herpes Proctitis, Dysuria, Fever

37
127 46
Fibrodysplasia ossificans prog... is listed (or ranked) 37 on the list The Scariest Diseases of All Time

38
119 38
Prostate cancer with bone meta... is listed (or ranked) 38 on the list The Scariest Diseases of All Time

39
185 48
Rabies is listed (or ranked) 39 on the list The Scariest Diseases of All Time
BrandiWolf added Rabies

40
110 59
Typhoid fever is listed (or ranked) 40 on the list The Scariest Diseases of All Time
Typhoid fever Fatigue, Abdominal pain, Fever

41
121 54
Amyotrophic lateral sclerosis is listed (or ranked) 41 on the list The Scariest Diseases of All Time
Amyotrophic lateral sclerosis Hyperreflexia, Fasciculation, Slurred Speech

42
97 42
Pulmonary embolism is listed (or ranked) 42 on the list The Scariest Diseases of All Time
Pulmonary embolism Dyspnea, Collapse, Hemoptysis

43
100 53
Crohn's disease is listed (or ranked) 43 on the list The Scariest Diseases of All Time
Crohn's disease Autoimmune hemolytic anemia, Scleritis, Fever

44
78 64
Kawasaki disease is listed (or ranked) 44 on the list The Scariest Diseases of All Time
Kawasaki disease Joint pain, Lymphadenopathy, Strawberry tongue

45
77 59
Hantavirus Infection is listed (or ranked) 45 on the list The Scariest Diseases of All Time

46
82 49
Lepromatous leprosy is listed (or ranked) 46 on the list The Scariest Diseases of All Time

47
74 18
Ovarian cancer is listed (or ranked) 47 on the list The Scariest Diseases of All Time
possumprincess added Ovarian cancer Pelvic pain, Dyspnea, Bloating

48
96 118
Influenza is listed (or ranked) 48 on the list The Scariest Diseases of All Time
Influenza Watery eyes, Red eye, Fever

49
73 59
Dissociative identity disorder is listed (or ranked) 49 on the list The Scariest Diseases of All Time

50
49 15
Primary Amebic Meningoencephal... is listed (or ranked) 50 on the list The Scariest Diseases of All Time
DevonteJohnsen added Primary Amebic Meningoencephalitis