"Top 10 Anime Betrayals" may be a meme, but that doesn't mean there aren't plenty of actual betrayals populating the world of anime. Some of these betrayals are pretty heartbreaking, especially those that come from the people the victim is closest to.
One particularly harrowing example of an anime character betrayed by someone they love is Sasuke Uchiha, whose older brother eliminated their entire clan, leaving him as the only survivor. There's also Nina Tucker from FMA, whose father fused her with the family pet to advance his career. Less well known is Yona, whose childhood friend slew her father in order to get his own revenge on him.
Which of these betrayals are the most painful? Be sure to vote them up!