15 Anime Best Friends Who Started Off On The Wrong Foot

The rift between Quincy and Shinigami is a deep one, and it's the reason why when Uryu and Ichigo first meet, they don't get along. Uryu hates all Shinigami, both because of their persecution of Quincy in the past, and because they failed to protect his grandfather from a Hollow. 

When he first meets Ichigo, he tells him straight up that he hates Shinigami and he hates Ichigo because he's a Shinigami. At this point, Ichigo barely knows what a Shinigami is, so he's incredibly confused by the sudden burst of hostility. As they get to know each other both in school and in a more supernatural context, both of them realize that there's a lot more to the other person than what category they belong to. 

It's hard to imagine a time when Ash and Pikachu weren't a dream team, but a relationship between a Pokémon and their trainer isn't always instant. When Ash first received Pikachu from Professor Oak, the electric Pokémon wasn't exactly interested in being trained. Pikachu resisted Ash's attempts to command him, refused to stay in the Pokéball, and electrocuted him whenever he got frustrated. 

In order to make things work with his new companion, Ash has to let Pikachu decide some things for himself, like letting him stay outside of the Pokéball.

Teruki Hanazawa first appears as an arc villain. Like Mob, he has psychic powers, but unlike Mob, he uses them to force others into worshipping him. Through an all-out battle, Mob helps Teruki realize that having powers doesn't make him better than everyone else, and his life would be greatly improved if he focused on getting along with others instead of trying to make them subservient. 

After Teruki changed his behavior, Mob was more than happy to be friends with him. The two not only work together to deal with rogue spirits, but they also spend a lot of time shopping together - Mob is one of the only people who actually appreciates Teru's out-there fashion sense.

Befriending a screaming dude wearing a boar's head and threatening you with a sword is no easy task, which is probably why Inosuke and Tanjiro don't exactly start off on the right foot. Well, that and the fact that he tries to destroy the box Nezuko's in because he knows there's a demon in there. 

Luckily, he doesn't hurt Nezuko, and he does eventually start working together with Tanjiro and Zenitsu to fight demons that are actual threats. Overall, he's an excellent member of the team - as long as you ignore the fact that he can't remember what Tanjiro's name is. 

At first, Gajeel is part of a rival guild called Phantom Lord that actually serves as an arc villain. In fact, he's the guild's strongest member. Because Phantom does things like destroy other guild's property and literally crucify the guilds they defeat, Fairy Tail isn't going to stand by and let it happen.

But after their fight, Gajeel ends up joining Fairy Tail. At first, Natsu and Gajeel are constantly bickering with each other, arguing about things that don't especially matter like “who has the strongest cat?” But after battling alongside each other, they develop a sense of camaraderie and respect for one another. 

It's hard to get much worse than Vegeta and Goku's relationship when they first meet. Vegeta is actively attempting to end Goku's life. He thinks he's a pathetic example of Saiyankind, so he's absolutely enraged to discover that Goku is stronger than he is. While he does eventually graduate from actively trying to destroy him and becomes his ally, he still desperately wants to prove his superiority and treats him with total disdain. 

It's only after they've been working together for years that Vegeta finally lets go of the idea. Even then, he still wants to defeat Goku as a personal challenge to himself - he just doesn't need to be superior to him anymore, because they're friends who care about each other.