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The Best 2000s ABC Comedy Shows

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List RulesUpvote your favorite ABC Comedies that aired on TV in the '00s

These are the very best 2000s ABC comedy shows, ranked from best to worst by user votes. The best '00s ABC comedy shows cover a lot of ground, from traditional sitcoms to shows that blurred the line between comedy and drama. Some of the top 2000s ABC comedy series mixed in poignant moments while other '00s ABC comedies stuck to the funny stuff. With this list of 200s ABC comedy shows, you can let the world know which approach worked best.

Which sitcoms will you find on our top 2000s ABC comedy shows list? Scrubs only ran on ABC from 2009-2010, but it still goes down as one of the network's best comedies of the 2000s. One of the longest running '00s ABC comedy series was According to Jim, a family sitcom that ran from 2001-2009.

Desperate Housewives combined big drama with hilarious comedy during its eight seasons on ABC. Other household sitcoms that appear on this 2000s ABC comedies list include My Wife and Kids, 8 Simple Rules, and George Lopez.

Which ABC comedy show from the 2000s is your favorite? Vote up the shows you remember most fondly and downvote the shows aren't among the best ABC shows of the 2000s. Rerank to show off your own version and don't forget to add any '00s ABC comedies we missed!
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  • 1
    George Lopez is listed (or ranked) 1 on the list The Best 2000s ABC Comedy Shows
    33
    8

    George Lopez

    Sandra Bullock, George Lopez

    Premiered2002

    George Lopez, also known as The George Lopez Show, is an American television sitcom created by... more on Wikipedia
  • 2
    Ugly Betty is listed (or ranked) 2 on the list The Best 2000s ABC Comedy Shows
    21
    9

    Ugly Betty

    America Ferrera, Eric Mabius

    Premiered2006

    Ugly Betty (ABC, 2006) is an American comedy-drama television series developed by Silvio... more on Wikipedia
  • 3
    Desperate Housewives is listed (or ranked) 3 on the list The Best 2000s ABC Comedy Shows
    22
    10

    Desperate Housewives

    Teri Hatcher, Felicity Huffman

    Premiered2004

    Desperate Housewives (ABC, 2004) is an American mystery comedy-drama television series created... more on Wikipedia

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  • 4
    Hope & Faith is listed (or ranked) 4 on the list The Best 2000s ABC Comedy Shows
    15
    8

    Hope & Faith

    Megan Fox, Kelly Ripa

    Premiered2003

    Hope & Faith is an American sitcom, starring Faith Ford and Kelly Ripa. It originally aired on... more on Wikipedia
  • 5
    Samantha Who? is listed (or ranked) 5 on the list The Best 2000s ABC Comedy Shows
    11
    6

    Samantha Who?

    Christina Applegate, Jennifer Esposito

    Premiered2007

    Samantha Who? is an American television sitcom that originally aired on ABC from October 15,... more on Wikipedia

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  • 6
    Cougar Town is listed (or ranked) 6 on the list The Best 2000s ABC Comedy Shows
    13
    10

    Cougar Town

    Courteney Cox, Christa Miller

    Premiered2009

    Cougar Town is an American television sitcom that ran for 102 episodes over six seasons, from... more on Wikipedia
  • 7
    Whose Line Is It Anyway? is listed (or ranked) 7 on the list The Best 2000s ABC Comedy Shows
    20
    20

    Whose Line Is It Anyway?

    Ryan Stiles, Colin Mochrie

    Premiered1998

    Whose Line Is It Anyway? (ABC, 1998-2207, The CW, 2013) is an American improvisational comedy... more on Wikipedia
  • 8
    Scrubs is listed (or ranked) 8 on the list The Best 2000s ABC Comedy Shows
    10
    8

    Scrubs

    Zach Braff, Donald Faison

    Premiered2001

    Scrubs (NBC, 2001) is an American medical comedy-drama television series created by Bill... more on Wikipedia

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  • 9
    Carpoolers is listed (or ranked) 9 on the list The Best 2000s ABC Comedy Shows
    9
    9

    Carpoolers

    Bridgette Wilson, Jerry O'Connell

    Premiered2007

    Carpoolers is an American single-camera comedy series, that aired on ABC from October 2, 2007... more on Wikipediaamazon_watch buy button
  • 10
    Life with Bonnie is listed (or ranked) 10 on the list The Best 2000s ABC Comedy Shows
    7
    7

    Life with Bonnie

    Bonnie Hunt, Mark Derwin

    Premiered2002

    Life with Bonnie is an ABC television sitcom that originally aired from 2002 to 2004. The show... more on Wikipediaamazon_watch buy button
  • 11
    Clerks: The Animated Series is listed (or ranked) 11 on the list The Best 2000s ABC Comedy Shows
    9
    10

    Clerks: The Animated Series

    Brian O'Halloran, Jeff Anderson

    Premiered2000

    Clerks is an American animated sitcom based on Kevin Smith's 1994 comedy of the same name. It... more on Wikipediaamazon_watch buy button

    More Clerks: The Animated Series 

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  • 12
    8 Simple Rules is listed (or ranked) 12 on the list The Best 2000s ABC Comedy Shows
    13
    18

    8 Simple Rules

    Katey Sagal, Kaley Cuoco

    Premiered2002

    8 Simple Rules is an American sitcom, originally starring John Ritter and Katey Sagal. It... more on Wikipedia
  • 13
    My Wife and Kids is listed (or ranked) 13 on the list The Best 2000s ABC Comedy Shows
    13
    20

    My Wife and Kids

    Damon Wayans, Tisha Campbell-Martin

    Premiered2001

    My Wife & Kids (ABC, 2001) is an American sitcom television series created by Don Reo and... more on Wikipedia
  • 14
    Jake in Progress is listed (or ranked) 14 on the list The Best 2000s ABC Comedy Shows
    4
    9

    Jake in Progress

    Julie Bowen, John Stamos

    Premiered2005

    Jake in Progress is an American comedy series broadcast on ABC from 2005 to 2006. Created by... more on Wikipediaamazon_watch buy button
  • 15
    Dot Comedy is listed (or ranked) 15 on the list The Best 2000s ABC Comedy Shows
    4
    10

    Dot Comedy

    Annabelle Gurwitch, Randy Sklar

    Premiered2000

    Dot Comedy is a television series that attempted to use humor found on the internet to... more on Wikipediaamazon_watch buy button
  • 16
    Dharma & Greg is listed (or ranked) 16 on the list The Best 2000s ABC Comedy Shows
    7
    16

    Dharma & Greg

    Jenna Elfman, Thomas Gibson

    Premiered1997

    Dharma & Greg is an American television sitcom that aired from September 24, 1997, to April... more on Wikipediaamazon_watch buy button
  • 17
    According to Jim is listed (or ranked) 17 on the list The Best 2000s ABC Comedy Shows
    12
    24

    According to Jim

    James Belushi, Courtney Thorne-Smith

    Premiered2001

    According to Jim is an American sitcom television series starring Jim Belushi in the title... more on Wikipedia

    More According to Jim 

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  • 18
    Better Off Ted is listed (or ranked) 18 on the list The Best 2000s ABC Comedy Shows
    5
    18

    Better Off Ted

    Jay Harrington, Portia de Rossi

    Premiered2009

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  • 19
    Less than Perfect is listed (or ranked) 19 on the list The Best 2000s ABC Comedy Shows
    3
    20

    Less than Perfect

    Sara Rue, Zachary Levi

    Premiered2002

    Less Than Perfect is an American sitcom created by Terri Minsky and starring Sara Rue and... more on Wikipedia
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