drama The Best 2000s Drama Series  

Ranker TV
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List Rules Vote up your favorite dramas that aired on TV in the 2000s

In the mood to catch up some TV you might have missed? This is a good place to start. These are the best 2000s drama series, ranked from best to worst by user votes. From 2000s drama TV series about serial killers, to other good 2000s drama series about mob bosses, a mysterious island, and even vampires!

What shows will you find on this best 2000s drama series list? The Sopranos appears near the top of our list. The 2007 finale of this great 2000s drama show pulled in a whopping 11.9 million viewers who wanted to see how this epic mob story would end. Another good HBO drama from the 2000s was The Wire, starring Dominic West, Idris Alba and Michael K. Williams.

Medical dramas were also quite popular in the 2000s with Grey's Anatomy among the best. Other good shows on this top 2000s drama series list include The Vampire Diaries, Law & Order: Special Victims Unit and Dexter.

Which great 2000s drama should get the top spot on this list? Vote up your favorites!
list ordered by

1
23 10
Breaking Bad is listed (or ranked) 1 on the list The Best 2000s Drama Series
Breaking Bad Bryan Cranston, Aaron Paul, Anna Gunn Breaking Bad is an American crime drama television series created and produced by Vince Gilligan. The show originally aired on the AMC network for five seasons, from January 20, 2008, to ...more

2
14 5
Prison Break is listed (or ranked) 2 on the list The Best 2000s Drama Series
Prison Break Dominic Purcell, Wentworth Miller, Amaury Nolasco Prison Break is an American television serial drama created by Paul Scheuring, that was broadcast on Fox for four seasons, from 2005 until 2009. The series revolves around two brothers; one has ...more

3
12 5
Sons of Anarchy is listed (or ranked) 3 on the list The Best 2000s Drama Series
Sons of Anarchy Charlie Hunnam, Katey Sagal, Mark Boone Junior Watch for Free with Amazon Prime Free Trial Sons of Anarchy is an American crime drama television series created by Kurt Sutter, about the lives of a close-knit outlaw motorcycle club operating in Charming, a fictional town in ...more

4
16 9
The Sopranos is listed (or ranked) 4 on the list The Best 2000s Drama Series
The Sopranos James Gandolfini, Lorraine Bracco, Edie Falco Watch for Free with Amazon Prime Free Trial The Sopranos is an American crime drama television series created by David Chase. Revolving around the fictional New Jersey-based Italian-American mobster Tony Soprano, the show portrays the ...more

5
18 12
Dexter is listed (or ranked) 5 on the list The Best 2000s Drama Series
Dexter Michael C. Hall, Jennifer Carpenter, David Zayas Dexter is an American television drama series. Set in Miami, the series centers on Dexter Morgan, a blood spatter pattern analyst for Miami Metro Police Department who also leads a secret life ...more

6
14 9
House is listed (or ranked) 6 on the list The Best 2000s Drama Series
House Hugh Laurie, Omar Epps, Robert Sean Leonard House is an American television medical drama that originally ran on the Fox network for eight seasons, from November 16, 2004 to May 21, 2012. The show's main character is Dr. Gregory House, a ...more

7
9 5
ER is listed (or ranked) 7 on the list The Best 2000s Drama Series
ER Anthony Edwards, George Clooney, Julianna Margulies ER is an American medical drama television series created by novelist Michael Crichton that aired on NBC from September 19, 1994, to April 2, 2009. It was produced by Constant c Productions and ...more

8
15 12
Lost is listed (or ranked) 8 on the list The Best 2000s Drama Series
Lost Naveen Andrews, Matthew Fox, Jorge Garcia Lost is an American television drama series that originally aired on the American Broadcasting Company from September 22, 2004, to May 23, 2010, over six seasons, comprising a total of 121 ...more

9
12 9
The Wire is listed (or ranked) 9 on the list The Best 2000s Drama Series
The Wire Dominic West, Lance Reddick, Sonja Sohn Watch for Free with Amazon Prime Free Trial The Wire is an American crime drama television series set and produced in and around Baltimore, Maryland. Created and primarily written by author and former police reporter David Simon, the ...more

10
9 6
Law & Order: Special Victims U... is listed (or ranked) 10 on the list The Best 2000s Drama Series
Law & Order: Special Victims Unit Mariska Hargitay, Christopher Meloni, Ice-T Law & Order: Special Victims Unit is an American police procedural, legal, crime drama television series set in New York City, where it is also primarily produced. In the style of the ...more

11
13 11
Criminal Minds is listed (or ranked) 11 on the list The Best 2000s Drama Series
Criminal Minds Shemar Moore, Matthew Gray Gubler, Thomas Gibson Criminal Minds is an American police-procedural television program that premiered September 22, 2005, on CBS. The series follows a team of profilers from the FBI's Behavioral Analysis Unit based ...more

12
9 7
Law & Order is listed (or ranked) 12 on the list The Best 2000s Drama Series
Law & Order Jerry Orbach, Jesse L. Martin, Dennis Farina Law & Order is an American police procedural and legal drama television series, created by Dick Wolf and part of the Law & Order franchise. It originally aired on NBC and, in ...more

The Best 2000s Historical Drama Series

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Castle is listed (or ranked) 13 on the list The Best 2000s Drama Series
Castle Nathan Fillion, Stana Katic, Susan Sullivan Castle is an American crime drama television series, which premiered on ABC on March 9, 2009. The series is produced jointly by Beacon Pictures and ABC Studios. Created by Andrew W. Marlowe, it ...more

14
14 14
The Vampire Diaries is listed (or ranked) 14 on the list The Best 2000s Drama Series
The Vampire Diaries Nina Dobrev, Paul Wesley, Ian Somerhalder The Vampire Diaries is an American supernatural drama television series developed by Kevin Williamson and Julie Plec, based on the popular book series of the same name written by L. J. Smith. ...more

15
9 9
One Tree Hill is listed (or ranked) 15 on the list The Best 2000s Drama Series
One Tree Hill Chad Michael Murray, James Lafferty, Hilarie Burton One Tree Hill is an American television drama series created by Mark Schwahn, which premiered on September 23, 2003 on The WB. After the series' third season, The WB merged with UPN to form The ...more

16
8 8
bones is listed (or ranked) 16 on the list The Best 2000s Drama Series
bones Emily Deschanel, David Boreanaz, Michaela Conlin Bones is an American crime procedural comedy-drama television series that premiered on Fox in the United States on September 13, 2005. The show is based on forensic anthropology and forensic ...more

17
3 3
The Tudors is listed (or ranked) 17 on the list The Best 2000s Drama Series
Sazonana added The Tudors Jonathan Rhys Meyers, Henry Cavill, Anthony Brophy The Tudors is a British-Irish-Canadian historical fiction television series set primarily in sixteenth-century England, created by Michael Hirst and produced for the American premium cable ...more

The Most Annoying TV and Film Characters Ever

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NCIS is listed (or ranked) 18 on the list The Best 2000s Drama Series
NCIS Mark Harmon, Michael Weatherly, Pauley Perrette NCIS is an American police procedural drama television series, revolving around a fictional team of special agents from the Naval Criminal Investigative Service, which conducts criminal ...more

19
11 12
Grey's Anatomy is listed (or ranked) 19 on the list The Best 2000s Drama Series
Grey's Anatomy Ellen Pompeo, Justin Chambers, Chandra Wilson Grey's Anatomy is an American medical soap opera television series that premiered on American Broadcasting Company as a mid-season replacement on March 27, 2005. The series has aired eleven ...more

20
7 8
24 is listed (or ranked) 20 on the list The Best 2000s Drama Series
24 Kiefer Sutherland, Mary Lynn Rajskub, Carlos Bernard Watch for Free with Amazon Prime Free Trial 24 is an American television series produced for the Fox network created by Joel Surnow and Robert Cochran, and starring Kiefer Sutherland as Counter Terrorist Unit agent Jack Bauer. Each ...more

21
6 7
Smallville is listed (or ranked) 21 on the list The Best 2000s Drama Series
Smallville Tom Welling, Michael Rosenbaum, Allison Mack Smallville is an American television series developed by writer-producers Alfred Gough and Miles Millar, based on the DC Comics character Superman created by Jerry Siegel and Joe Shuster. The ...more

22
5 6
The Mentalist is listed (or ranked) 22 on the list The Best 2000s Drama Series
The Mentalist Simon Baker, Robin Tunney, Tim Kang The Mentalist is an American police procedural television series that ran from September 23, 2008 until February 18, 2015, broadcasting 151 episodes over seven seasons, on CBS. The show was ...more

The Best 2000s NBC Dramas

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4 5
Veronica Mars is listed (or ranked) 23 on the list The Best 2000s Drama Series
Veronica Mars Kristen Bell, Percy Daggs III, Jason Dohring Watch for Free with Amazon Prime Free Trial Veronica Mars is an American mystery drama television series created by screenwriter Rob Thomas. The series is set in the fictional town of Neptune, California, and stars Kristen Bell as the ...more

24
9 11
Fringe is listed (or ranked) 24 on the list The Best 2000s Drama Series
Fringe Anna Torv, Joshua Jackson, Jasika Nicole Watch for Free with Amazon Prime Free Trial Fringe is an American science fiction television series created by J. J. Abrams, Alex Kurtzman, and Roberto Orci. It premiered on the Fox Broadcasting network on September 9, 2008, and concluded ...more

25
4 6
White Collar is listed (or ranked) 25 on the list The Best 2000s Drama Series
White Collar Matt Bomer, Tim DeKay, Willie Garson White Collar is a USA Network television series created by Jeff Eastin, starring Tim DeKay as FBI Special Agent Peter Burke and Matt Bomer as Neal Caffrey, a highly intelligent and ...more

26
10 13
True Blood is listed (or ranked) 26 on the list The Best 2000s Drama Series
True Blood Anna Paquin, Stephen Moyer, Sam Trammell Watch for Free with Amazon Prime Free Trial True Blood is an American television drama series produced and created by Alan Ball. It is based on The Southern Vampire Mysteries series of novels by Charlaine Harris, detailing the ...more

27
2 4
The Borgias is listed (or ranked) 27 on the list The Best 2000s Drama Series
Sazonana added The Borgias Jeremy Irons, François Arnaud, Holliday Grainger The Borgias is an historical-fiction drama television series created by Neil Jordan; it debuted in 2011 and was canceled in 2013. The series is set around the turn of the 16th century and ...more

The Best Movies Based on TV Shows

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CSI: Crime Scene Investigation is listed (or ranked) 28 on the list The Best 2000s Drama Series
CSI: Crime Scene Investigation Laurence Fishburne, Marg Helgenberger, George Eads CSI: Crime Scene Investigation is an American crime drama television series that premiered on CBS on October 6, 2000. The show was created by Anthony E. Zuiker and produced by Jerry Bruckheimer. ...more

29
1 3
Alias is listed (or ranked) 29 on the list The Best 2000s Drama Series
sunfyre added Alias Jennifer Garner, Ron Rifkin, Carl Lumbly Alias is an American spy-action television series created by J. J. Abrams, which was broadcast on ABC for five seasons, from September 30, 2001, to May 22, 2006. It stars Jennifer Garner as ...more

30
5 8
Mad Men is listed (or ranked) 30 on the list The Best 2000s Drama Series
Mad Men Jon Hamm, Elisabeth Moss, Vincent Kartheiser Mad Men is an American period drama television series created by Matthew Weiner. The series premiered on July 19, 2007 on the cable network AMC and is produced by Lionsgate Television. The ...more

31
5 8
7th Heaven is listed (or ranked) 31 on the list The Best 2000s Drama Series
7th Heaven Stephen Collins, Catherine Hicks, Jessica Biel Watch for Free with Amazon Prime Free Trial 7th Heaven is an American family drama television series, created and produced by Brenda Hampton. The series premiered on August 26, 1996, on The WB, the first time that the network aired Monday ...more

32
5 8
Burn Notice is listed (or ranked) 32 on the list The Best 2000s Drama Series
Burn Notice Jeffrey Donovan, Gabrielle Anwar, Bruce Campbell Burn Notice is an American television series created by Matt Nix which originally aired on the USA Network from June 28, 2007 to September 12, 2013. The show stars Jeffrey Donovan, Gabrielle ...more

The Best HBO Series of the 2000s

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2 5
Gossip Girl is listed (or ranked) 33 on the list The Best 2000s Drama Series
Sazonana added Gossip Girl Blake Lively, Leighton Meester, Penn Badgley Gossip Girl is an American teen drama television series based on the book series of the same name written by Cecily von Ziegesar. The series, created by Josh Schwartz and Stephanie Savage, ...more

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1 5
Grimm is listed (or ranked) 34 on the list The Best 2000s Drama Series
sunfyre added Grimm David Giuntoli, Silas Weir Mitchell, Sasha Roiz Grimm is an American police procedural fantasy television drama series. It debuted in the U.S. on NBC on October 28, 2011. The show has been described as "a cop drama—with a twist... a dark ...more

35
5 10
CSI: NY is listed (or ranked) 35 on the list The Best 2000s Drama Series
CSI: NY Gary Sinise, Carmine Giovinazzo, Hill Harper CSI: NY is an American police procedural television series that ran on CBS from September 22, 2004 to February 22, 2013 for a total of nine seasons and 197 original episodes. The show follows ...more

36
3 8
Desperate Housewives is listed (or ranked) 36 on the list The Best 2000s Drama Series
Desperate Housewives Teri Hatcher, Felicity Huffman, Marcia Cross Desperate Housewives is an American television comedy-drama-mystery series created by Marc Cherry and produced by ABC Studios and Cherry Productions. It aired Sundays at 9 P.M. Eastern/8 P.M. ...more

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3 8
Californication is listed (or ranked) 37 on the list The Best 2000s Drama Series
Californication David Duchovny, Natascha McElhone, Evan Handler Watch for Free with Amazon Prime Free Trial Californication is an American comedy-drama television series created by Tom Kapinos, which aired for seven seasons on Showtime from August 13, 2007 to June 29, 2014. The show follows New Yorker ...more

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2 7
The Good Wife is listed (or ranked) 38 on the list The Best 2000s Drama Series
The Good Wife Julianna Margulies, Chris Noth, Josh Charles Watch for Free with Amazon Prime Free Trial The Good Wife is an American television legal and political drama that premiered on CBS on September 22, 2009. The series was created by Robert King and Michelle King. It stars Julianna ...more

39
2 8
NCIS: Los Angeles is listed (or ranked) 39 on the list The Best 2000s Drama Series
NCIS: Los Angeles Chris O'Donnell, Daniela Ruah, Barrett Foa NCIS: Los Angeles is an American television series combining elements of the military drama and police procedural genres, which premiered on the CBS network on September 22, 2009. NCIS: Los ...more

40
4 11
CSI: Miami is listed (or ranked) 40 on the list The Best 2000s Drama Series
CSI: Miami David Caruso, Emily Procter, Adam Rodriguez CSI: Miami is an American police procedural television series that ran from September 23, 2002, to April 8, 2012, on CBS. It is the first spin-off of CSI: Crime Scene Investigation. The pilot ...more

41
0 4
Soul Food is listed (or ranked) 41 on the list The Best 2000s Drama Series
sunfyre added Soul Food Boris Kodjoe, Nicole Ari Parker, Vanessa A. Williams Soul Food: The Series is a television drama that aired Wednesday nights on Showtime from June 28, 2000 to May 26, 2004. Created by filmmaker George Tillman, Jr. and developed for television by ...more