Entertainment

The Best 2000s Drama Series  

Ranker TV
1.6k votes 283 voters 7.3k views 45 items

List Rules Vote up your favorite dramas that aired on TV in the 2000s

In the mood to catch up some TV you might have missed? This is a good place to start. These are the best 2000s drama series, ranked from best to worst by user votes. From 2000s drama TV series about serial killers, to other good 2000s drama series about mob bosses, a mysterious island, and even vampires!

What shows will you find on this best 2000s drama series list? The Sopranos appears near the top of our list. The 2007 finale of this great 2000s drama show pulled in a whopping 11.9 million viewers who wanted to see how this epic mob story would end. Another good HBO drama from the 2000s was The Wire, starring Dominic West, Idris Alba and Michael K. Williams.

Medical dramas were also quite popular in the 2000s with Grey's Anatomy among the best. Other good shows on this top 2000s drama series list include The Vampire Diaries, Law & Order: Special Victims Unit and Dexter.

Which great 2000s drama should get the top spot on this list? Vote up your favorites!
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26
Monk is listed (or ranked) 26 on the list The Best 2000s Drama Series
Tony Shalhoub, Jason Gray-Stanford, Ted Levine
Monk is an American comedy-drama detective mystery television series created by Andy Breckman and starring Tony Shalhoub as the eponymous character, Adrian Monk. It originally ran from 2002 to ...more
27
Dollhouse is listed (or ranked) 27 on the list The Best 2000s Drama Series
Eliza Dushku, Harry Lennix, Fran Kranz
Dollhouse is an American science fiction television series created by writer and director Joss Whedon under Mutant Enemy Productions. It premiered on February 13, 2009, on the Fox network and ...more
28
The Wire is listed (or ranked) 28 on the list The Best 2000s Drama Series
Dominic West, Lance Reddick, Sonja Sohn
Watch for Free with Amazon Prime Free Trial The Wire is an American drama television series set and produced in and around Baltimore, Maryland. Created and primarily written by author and former police reporter David Simon, the series was ...more
29
Grimm is listed (or ranked) 29 on the list The Best 2000s Drama Series
sunfyre added David Giuntoli, Silas Weir Mitchell, Sasha Roiz
Grimm is an American police procedural fantasy television drama series. It debuted in the U.S. on NBC on October 28, 2011. The show has been described as "a cop drama—with a twist... a dark ...more
30
CSI: NY is listed (or ranked) 30 on the list The Best 2000s Drama Series
Gary Sinise, Carmine Giovinazzo, Hill Harper
CSI: NY is an American police procedural television series that ran on CBS from September 22, 2004 to February 22, 2013 for a total of nine seasons and 197 original episodes. The show follows ...more
31
Fringe is listed (or ranked) 31 on the list The Best 2000s Drama Series
Anna Torv, Joshua Jackson, Jasika Nicole
Watch for Free with Amazon Prime Free Trial Fringe is an American science fiction television series created by J. J. Abrams, Alex Kurtzman, and Roberto Orci. It premiered on the Fox Broadcasting network on September 9, 2008, and concluded ...more
32
The Good Wife is listed (or ranked) 32 on the list The Best 2000s Drama Series
Julianna Margulies, Chris Noth, Josh Charles
Watch for Free with Amazon Prime Free Trial The Good Wife is an American television legal and political drama that premiered on CBS on September 22, 2009. The series was created by Robert King and Michelle King. It stars Julianna ...more
33
The Mentalist is listed (or ranked) 33 on the list The Best 2000s Drama Series
Simon Baker, Robin Tunney, Tim Kang
The Mentalist is an American police procedural television series that ran from September 23, 2008 until February 18, 2015, broadcasting 151 episodes over seven seasons, on CBS. The show was ...more
34
Desperate Housewives is listed (or ranked) 34 on the list The Best 2000s Drama Series
Teri Hatcher, Felicity Huffman, Marcia Cross
Desperate Housewives is an American television comedy-drama-mystery series created by Marc Cherry and produced by ABC Studios and Cherry Productions. It aired Sundays at 9 P.M. Eastern/8 P.M. ...more
35
The Tudors is listed (or ranked) 35 on the list The Best 2000s Drama Series
Sazonana added Jonathan Rhys Meyers, Henry Cavill, Anthony Brophy
The Tudors is a British-Irish-Canadian historical fiction television series set primarily in sixteenth-century England, created by Michael Hirst and produced for the American premium cable ...more
36
NCIS: Los Angeles is listed (or ranked) 36 on the list The Best 2000s Drama Series
Chris O'Donnell, Daniela Ruah, Barrett Foa
NCIS: Los Angeles is an American television series combining elements of the military drama and police procedural genres, which premiered on the CBS network on September 22, 2009. NCIS: Los ...more
37
True Blood is listed (or ranked) 37 on the list The Best 2000s Drama Series
Anna Paquin, Stephen Moyer, Sam Trammell
Watch for Free with Amazon Prime Free Trial True Blood is an American television drama series produced and created by Alan Ball. It is based on The Southern Vampire Mysteries series of novels by Charlaine Harris, detailing the ...more
38
Gossip Girl is listed (or ranked) 38 on the list The Best 2000s Drama Series
Sazonana added Blake Lively, Leighton Meester, Penn Badgley
Gossip Girl is an American teen drama television series based on the book series of the same name written by Cecily von Ziegesar. The series, created by Josh Schwartz and Stephanie Savage, ...more
39
Entourage is listed (or ranked) 39 on the list The Best 2000s Drama Series
Kevin Connolly, Adrian Grenier, Kevin Dillon
Entourage is an American comedy-drama television series that premiered on HBO on July 18, 2004 and concluded on September 11, 2011, after eight seasons. The series was created and largely ...more
40
7th Heaven is listed (or ranked) 40 on the list The Best 2000s Drama Series
Stephen Collins, Catherine Hicks, Jessica Biel
Watch for Free with Amazon Prime Free Trial 7th Heaven is an American family drama television series, created and produced by Brenda Hampton. The series premiered on August 26, 1996, on The WB, the first time that the network aired Monday ...more
41
CSI: Miami is listed (or ranked) 41 on the list The Best 2000s Drama Series
David Caruso, Emily Procter, Adam Rodriguez
CSI: Miami is an American police procedural television series that ran from September 23, 2002, to April 8, 2012, on CBS. It is the first spin-off of the orignal series. The pilot episode was ...more
42
Mad Men is listed (or ranked) 42 on the list The Best 2000s Drama Series
Jon Hamm, Elisabeth Moss, Vincent Kartheiser
Mad Men is an American period drama television series created by Matthew Weiner. The series premiered on July 19, 2007 on the cable network AMC and is produced by Lionsgate Television. The ...more
43
The Borgias is listed (or ranked) 43 on the list The Best 2000s Drama Series
Sazonana added Jeremy Irons, François Arnaud, Holliday Grainger
The Borgias is an historical-fiction drama television series created by Neil Jordan; it debuted in 2011 and was canceled in 2013. The series is set around the turn of the 16th century and ...more
44
Californication is listed (or ranked) 44 on the list The Best 2000s Drama Series
David Duchovny, Natascha McElhone, Evan Handler
Watch for Free with Amazon Prime Free Trial Californication is an American comedy-drama television series created by Tom Kapinos, which aired for seven seasons on Showtime from August 13, 2007 to June 29, 2014. The show follows New Yorker ...more
45
Soul Food is listed (or ranked) 45 on the list The Best 2000s Drama Series
sunfyre added Boris Kodjoe, Nicole Ari Parker, Vanessa A. Williams
Soul Food: The Series is a television drama that aired Wednesday nights on Showtime from June 28, 2000 to May 26, 2004. Created by filmmaker George Tillman, Jr. and developed for television by ...more