Total Nerd The Best Villains Deadpool Has Ever Faced  

Ranker Comics
25.3k votes 3k voters 323.8k views 54 items

List Rules Vote up all your favorite villains that you love to see Deadpool go at it with! No heroes!

The Merc with a Mouth, or Deadpool, was created in 1991 by writer Fabian Nicieza and comic illustrator Rob Liefeld. Though Deadpool walks the line of being a villain himself, he's also fought some of the nastiest evil guys around to help save the planet and humankind... when the price is right, anyway. This anti-hero may not always feel the urge to save the day, he still displays an impressive rogue gallery, and we're here to show it to you.
 
We've listed all of Deadpool's greatest enemies on here. Who do you think is the best villain this comic book hero's ever encountered? Do you enjoy the rivalry between Deadpool and Madcap, or do you hold Death in a special place in your heart? 
Make sure to vote up all your favorite Deadpool villains, and vote down the ones you despise. Don't see the villain you love to hate on this list? Be sure to add them!
list ordered by

1
1,498 263
Carnage is listed (or ranked) 1 on the list The Best Villains Deadpool Has Ever Faced

2
1,089 316
Deathstroke is listed (or ranked) 2 on the list The Best Villains Deadpool Has Ever Faced

3
862 264
Evil Deadpool is listed (or ranked) 3 on the list The Best Villains Deadpool Has Ever Faced
Evil Deadpool

4
726 234
Apocalypse is listed (or ranked) 4 on the list The Best Villains Deadpool Has Ever Faced

5
791 290
Taskmaster is listed (or ranked) 5 on the list The Best Villains Deadpool Has Ever Faced

6
613 240
Death is listed (or ranked) 6 on the list The Best Villains Deadpool Has Ever Faced

7
543 234
Red Hulk is listed (or ranked) 7 on the list The Best Villains Deadpool Has Ever Faced

8
512 239
Magneto is listed (or ranked) 8 on the list The Best Villains Deadpool Has Ever Faced

9
434 199
Juggernaut is listed (or ranked) 9 on the list The Best Villains Deadpool Has Ever Faced

10
451 221
Mister Sinister is listed (or ranked) 10 on the list The Best Villains Deadpool Has Ever Faced

11
440 219
Loki is listed (or ranked) 11 on the list The Best Villains Deadpool Has Ever Faced

12
396 197
Doctor Doom is listed (or ranked) 12 on the list The Best Villains Deadpool Has Ever Faced

13
381 220
Sabretooth is listed (or ranked) 13 on the list The Best Villains Deadpool Has Ever Faced

14
293 224
Crossbones is listed (or ranked) 14 on the list The Best Villains Deadpool Has Ever Faced

15
327 260
BULLSEYE is listed (or ranked) 15 on the list The Best Villains Deadpool Has Ever Faced

16
274 227
Flash Thompson is listed (or ranked) 16 on the list The Best Villains Deadpool Has Ever Faced

17
168 116
Black Panther is listed (or ranked) 17 on the list The Best Villains Deadpool Has Ever Faced
Benjaminjeune added

18
243 222
Sentinel is listed (or ranked) 18 on the list The Best Villains Deadpool Has Ever Faced

19
234 215
Green Goblin is listed (or ranked) 19 on the list The Best Villains Deadpool Has Ever Faced
Marvel 1602

20
233 224
Daken is listed (or ranked) 20 on the list The Best Villains Deadpool Has Ever Faced

21
76 41
Ajax is listed (or ranked) 21 on the list The Best Villains Deadpool Has Ever Faced
Tyler Gammon added

22
215 218
Typhoid Mary is listed (or ranked) 22 on the list The Best Villains Deadpool Has Ever Faced

23
186 211
Black Mamba is listed (or ranked) 23 on the list The Best Villains Deadpool Has Ever Faced

24
188 226
Vertigo is listed (or ranked) 24 on the list The Best Villains Deadpool Has Ever Faced

25
168 205
Madcap is listed (or ranked) 25 on the list The Best Villains Deadpool Has Ever Faced

26
165 213
Blob is listed (or ranked) 26 on the list The Best Villains Deadpool Has Ever Faced

27
171 228
Dr. Otto Octavius is listed (or ranked) 27 on the list The Best Villains Deadpool Has Ever Faced

28
159 231
T-Ray is listed (or ranked) 28 on the list The Best Villains Deadpool Has Ever Faced

29
142 210
Tombstone is listed (or ranked) 29 on the list The Best Villains Deadpool Has Ever Faced

30
124 183
Beyonder is listed (or ranked) 30 on the list The Best Villains Deadpool Has Ever Faced

31
83 132
Man-Thing is listed (or ranked) 31 on the list The Best Villains Deadpool Has Ever Faced
Tim Cecil added

32
119 200
Sauron is listed (or ranked) 32 on the list The Best Villains Deadpool Has Ever Faced

33
119 202
Black Tom Cassidy is listed (or ranked) 33 on the list The Best Villains Deadpool Has Ever Faced

34
101 171
Shriek is listed (or ranked) 34 on the list The Best Villains Deadpool Has Ever Faced

35
110 191
Ghost is listed (or ranked) 35 on the list The Best Villains Deadpool Has Ever Faced

36
93 176
Arcade is listed (or ranked) 36 on the list The Best Villains Deadpool Has Ever Faced

37
104 198
Mister X is listed (or ranked) 37 on the list The Best Villains Deadpool Has Ever Faced

38
86 174
Doctor Bong is listed (or ranked) 38 on the list The Best Villains Deadpool Has Ever Faced

39
16 37
Slayback is listed (or ranked) 39 on the list The Best Villains Deadpool Has Ever Faced
Freddyjason added Slayback

40
82 173
Tiger Shark is listed (or ranked) 40 on the list The Best Villains Deadpool Has Ever Faced

41
84 184
Blockbuster is listed (or ranked) 41 on the list The Best Villains Deadpool Has Ever Faced

42
72 170
Black Talon is listed (or ranked) 42 on the list The Best Villains Deadpool Has Ever Faced

43
69 166
Bulldozer is listed (or ranked) 43 on the list The Best Villains Deadpool Has Ever Faced

44
76 181
Arclight is listed (or ranked) 44 on the list The Best Villains Deadpool Has Ever Faced

45
72 173
Headsman is listed (or ranked) 45 on the list The Best Villains Deadpool Has Ever Faced

46
69 167
Constrictor is listed (or ranked) 46 on the list The Best Villains Deadpool Has Ever Faced

47
65 159
Wrecker is listed (or ranked) 47 on the list The Best Villains Deadpool Has Ever Faced

48
66 166
Batroc the Leaper is listed (or ranked) 48 on the list The Best Villains Deadpool Has Ever Faced

49
62 160
Piledriver is listed (or ranked) 49 on the list The Best Villains Deadpool Has Ever Faced

50
58 153
Thunderball is listed (or ranked) 50 on the list The Best Villains Deadpool Has Ever Faced