Total Nerd The Best Villains Deadpool Has Ever Faced  

Ranker Comics
25.8k votes 3k voters 325k views 54 items

List Rules Vote up all your favorite villains that you love to see Deadpool go at it with! No heroes!

The Merc with a Mouth, or Deadpool, was created in 1991 by writer Fabian Nicieza and comic illustrator Rob Liefeld. Though Deadpool walks the line of being a villain himself, he's also fought some of the nastiest evil guys around to help save the planet and humankind... when the price is right, anyway. This anti-hero may not always feel the urge to save the day, he still displays an impressive rogue gallery, and we're here to show it to you.
 
We've listed all of Deadpool's greatest enemies on here. Who do you think is the best villain this comic book hero's ever encountered? Do you enjoy the rivalry between Deadpool and Madcap, or do you hold Death in a special place in your heart? 
Make sure to vote up all your favorite Deadpool villains, and vote down the ones you despise. Don't see the villain you love to hate on this list? Be sure to add them!
list ordered by

1
1,521 266
Carnage is listed (or ranked) 1 on the list The Best Villains Deadpool Has Ever Faced

2
1,102 325
Deathstroke is listed (or ranked) 2 on the list The Best Villains Deadpool Has Ever Faced

3
879 269
Evil Deadpool is listed (or ranked) 3 on the list The Best Villains Deadpool Has Ever Faced
Evil Deadpool

4
741 238
Apocalypse is listed (or ranked) 4 on the list The Best Villains Deadpool Has Ever Faced

5
805 292
Taskmaster is listed (or ranked) 5 on the list The Best Villains Deadpool Has Ever Faced

6
622 244
Death is listed (or ranked) 6 on the list The Best Villains Deadpool Has Ever Faced

7
552 239
Red Hulk is listed (or ranked) 7 on the list The Best Villains Deadpool Has Ever Faced

8
521 243
Magneto is listed (or ranked) 8 on the list The Best Villains Deadpool Has Ever Faced

9
446 204
Juggernaut is listed (or ranked) 9 on the list The Best Villains Deadpool Has Ever Faced

10
460 225
Mister Sinister is listed (or ranked) 10 on the list The Best Villains Deadpool Has Ever Faced

11
446 225
Loki is listed (or ranked) 11 on the list The Best Villains Deadpool Has Ever Faced

12
407 200
Doctor Doom is listed (or ranked) 12 on the list The Best Villains Deadpool Has Ever Faced

13
388 226
Sabretooth is listed (or ranked) 13 on the list The Best Villains Deadpool Has Ever Faced

14
334 264
BULLSEYE is listed (or ranked) 14 on the list The Best Villains Deadpool Has Ever Faced

15
299 229
Crossbones is listed (or ranked) 15 on the list The Best Villains Deadpool Has Ever Faced

16
176 120
Black Panther is listed (or ranked) 16 on the list The Best Villains Deadpool Has Ever Faced
Benjaminjeune added

17
278 233
Flash Thompson is listed (or ranked) 17 on the list The Best Villains Deadpool Has Ever Faced

18
249 226
Sentinel is listed (or ranked) 18 on the list The Best Villains Deadpool Has Ever Faced

19
241 218
Green Goblin is listed (or ranked) 19 on the list The Best Villains Deadpool Has Ever Faced
Marvel 1602

20
235 230
Daken is listed (or ranked) 20 on the list The Best Villains Deadpool Has Ever Faced

21
81 45
Ajax is listed (or ranked) 21 on the list The Best Villains Deadpool Has Ever Faced
Tyler Gammon added

22
221 222
Typhoid Mary is listed (or ranked) 22 on the list The Best Villains Deadpool Has Ever Faced

23
190 216
Black Mamba is listed (or ranked) 23 on the list The Best Villains Deadpool Has Ever Faced

24
191 230
Vertigo is listed (or ranked) 24 on the list The Best Villains Deadpool Has Ever Faced

25
171 210
Madcap is listed (or ranked) 25 on the list The Best Villains Deadpool Has Ever Faced