Total Nerd The Best Villains Deadpool Has Ever Faced  

Ranker Comics
25.1k votes 2.9k voters 323.3k views 54 items

List Rules Vote up all your favorite villains that you love to see Deadpool go at it with! No heroes!

The Merc with a Mouth, or Deadpool, was created in 1991 by writer Fabian Nicieza and comic illustrator Rob Liefeld. Though Deadpool walks the line of being a villain himself, he's also fought some of the nastiest evil guys around to help save the planet and humankind... when the price is right, anyway. This anti-hero may not always feel the urge to save the day, he still displays an impressive rogue gallery, and we're here to show it to you.
 
We've listed all of Deadpool's greatest enemies on here. Who do you think is the best villain this comic book hero's ever encountered? Do you enjoy the rivalry between Deadpool and Madcap, or do you hold Death in a special place in your heart? 
Make sure to vote up all your favorite Deadpool villains, and vote down the ones you despise. Don't see the villain you love to hate on this list? Be sure to add them!
list ordered by

1
1,488 260
Carnage is listed (or ranked) 1 on the list The Best Villains Deadpool Has Ever Faced

2
1,077 316
Deathstroke is listed (or ranked) 2 on the list The Best Villains Deadpool Has Ever Faced

3
855 262
Evil Deadpool is listed (or ranked) 3 on the list The Best Villains Deadpool Has Ever Faced
Evil Deadpool

4
722 231
Apocalypse is listed (or ranked) 4 on the list The Best Villains Deadpool Has Ever Faced

5
784 287
Taskmaster is listed (or ranked) 5 on the list The Best Villains Deadpool Has Ever Faced

6
608 236
Death is listed (or ranked) 6 on the list The Best Villains Deadpool Has Ever Faced

7
539 232
Red Hulk is listed (or ranked) 7 on the list The Best Villains Deadpool Has Ever Faced

8
507 239
Magneto is listed (or ranked) 8 on the list The Best Villains Deadpool Has Ever Faced

9
429 198
Juggernaut is listed (or ranked) 9 on the list The Best Villains Deadpool Has Ever Faced

10
450 218
Mister Sinister is listed (or ranked) 10 on the list The Best Villains Deadpool Has Ever Faced

11
436 218
Loki is listed (or ranked) 11 on the list The Best Villains Deadpool Has Ever Faced

12
393 196
Doctor Doom is listed (or ranked) 12 on the list The Best Villains Deadpool Has Ever Faced

13
378 220
Sabretooth is listed (or ranked) 13 on the list The Best Villains Deadpool Has Ever Faced

14
325 258
BULLSEYE is listed (or ranked) 14 on the list The Best Villains Deadpool Has Ever Faced

15
290 224
Crossbones is listed (or ranked) 15 on the list The Best Villains Deadpool Has Ever Faced

16
273 225
Flash Thompson is listed (or ranked) 16 on the list The Best Villains Deadpool Has Ever Faced

17
167 114
Black Panther is listed (or ranked) 17 on the list The Best Villains Deadpool Has Ever Faced
Benjaminjeune added

18
241 221
Sentinel is listed (or ranked) 18 on the list The Best Villains Deadpool Has Ever Faced

19
232 214
Green Goblin is listed (or ranked) 19 on the list The Best Villains Deadpool Has Ever Faced
Marvel 1602

20
233 223
Daken is listed (or ranked) 20 on the list The Best Villains Deadpool Has Ever Faced

21
75 40
Ajax is listed (or ranked) 21 on the list The Best Villains Deadpool Has Ever Faced
Tyler Gammon added

22
215 216
Typhoid Mary is listed (or ranked) 22 on the list The Best Villains Deadpool Has Ever Faced

23
186 209
Black Mamba is listed (or ranked) 23 on the list The Best Villains Deadpool Has Ever Faced

24
187 225
Vertigo is listed (or ranked) 24 on the list The Best Villains Deadpool Has Ever Faced

25
168 203
Madcap is listed (or ranked) 25 on the list The Best Villains Deadpool Has Ever Faced

26
164 212
Blob is listed (or ranked) 26 on the list The Best Villains Deadpool Has Ever Faced

27
171 226
Dr. Otto Octavius is listed (or ranked) 27 on the list The Best Villains Deadpool Has Ever Faced

28
159 229
T-Ray is listed (or ranked) 28 on the list The Best Villains Deadpool Has Ever Faced

29
142 208
Tombstone is listed (or ranked) 29 on the list The Best Villains Deadpool Has Ever Faced

30
124 181
Beyonder is listed (or ranked) 30 on the list The Best Villains Deadpool Has Ever Faced

31
83 130
Man-Thing is listed (or ranked) 31 on the list The Best Villains Deadpool Has Ever Faced
Tim Cecil added

32
119 198
Sauron is listed (or ranked) 32 on the list The Best Villains Deadpool Has Ever Faced

33
101 169
Shriek is listed (or ranked) 33 on the list The Best Villains Deadpool Has Ever Faced

34
118 200
Black Tom Cassidy is listed (or ranked) 34 on the list The Best Villains Deadpool Has Ever Faced

35
109 190
Ghost is listed (or ranked) 35 on the list The Best Villains Deadpool Has Ever Faced

36
104 196
Mister X is listed (or ranked) 36 on the list The Best Villains Deadpool Has Ever Faced

37
92 175
Arcade is listed (or ranked) 37 on the list The Best Villains Deadpool Has Ever Faced

38
16 35
Slayback is listed (or ranked) 38 on the list The Best Villains Deadpool Has Ever Faced
Freddyjason added Slayback

39
86 172
Doctor Bong is listed (or ranked) 39 on the list The Best Villains Deadpool Has Ever Faced

40
82 171
Tiger Shark is listed (or ranked) 40 on the list The Best Villains Deadpool Has Ever Faced

41
84 182
Blockbuster is listed (or ranked) 41 on the list The Best Villains Deadpool Has Ever Faced

42
72 168
Black Talon is listed (or ranked) 42 on the list The Best Villains Deadpool Has Ever Faced

43
76 179
Arclight is listed (or ranked) 43 on the list The Best Villains Deadpool Has Ever Faced

44
72 171
Headsman is listed (or ranked) 44 on the list The Best Villains Deadpool Has Ever Faced

45
69 165
Bulldozer is listed (or ranked) 45 on the list The Best Villains Deadpool Has Ever Faced

46
69 166
Constrictor is listed (or ranked) 46 on the list The Best Villains Deadpool Has Ever Faced

47
65 158
Wrecker is listed (or ranked) 47 on the list The Best Villains Deadpool Has Ever Faced

48
66 164
Batroc the Leaper is listed (or ranked) 48 on the list The Best Villains Deadpool Has Ever Faced

49
62 159
Piledriver is listed (or ranked) 49 on the list The Best Villains Deadpool Has Ever Faced

50
58 152
Thunderball is listed (or ranked) 50 on the list The Best Villains Deadpool Has Ever Faced