Total Nerd The Best Villains Deadpool Has Ever Faced  

Ranker Comics
26.4k votes 3.1k voters 326.3k views 54 items

List Rules Vote up all your favorite villains that you love to see Deadpool go at it with! No heroes!

The Merc with a Mouth, or Deadpool, was created in 1991 by writer Fabian Nicieza and comic illustrator Rob Liefeld. Though Deadpool walks the line of being a villain himself, he's also fought some of the nastiest evil guys around to help save the planet and humankind... when the price is right, anyway. This anti-hero may not always feel the urge to save the day, he still displays an impressive rogue gallery, and we're here to show it to you.
 
We've listed all of Deadpool's greatest enemies on here. Who do you think is the best villain this comic book hero's ever encountered? Do you enjoy the rivalry between Deadpool and Madcap, or do you hold Death in a special place in your heart? 
Make sure to vote up all your favorite Deadpool villains, and vote down the ones you despise. Don't see the villain you love to hate on this list? Be sure to add them!
list ordered by

1
1,551 272
Carnage is listed (or ranked) 1 on the list The Best Villains Deadpool Has Ever Faced

2
1,121 332
Deathstroke is listed (or ranked) 2 on the list The Best Villains Deadpool Has Ever Faced

3
900 276
Evil Deadpool is listed (or ranked) 3 on the list The Best Villains Deadpool Has Ever Faced
Evil Deadpool

4
755 245
Apocalypse is listed (or ranked) 4 on the list The Best Villains Deadpool Has Ever Faced

5
827 296
Taskmaster is listed (or ranked) 5 on the list The Best Villains Deadpool Has Ever Faced

6
633 253
Death is listed (or ranked) 6 on the list The Best Villains Deadpool Has Ever Faced

7
563 246
Red Hulk is listed (or ranked) 7 on the list The Best Villains Deadpool Has Ever Faced

8
536 247
Magneto is listed (or ranked) 8 on the list The Best Villains Deadpool Has Ever Faced

9
466 207
Juggernaut is listed (or ranked) 9 on the list The Best Villains Deadpool Has Ever Faced

10
477 227
Mister Sinister is listed (or ranked) 10 on the list The Best Villains Deadpool Has Ever Faced

11
461 229
Loki is listed (or ranked) 11 on the list The Best Villains Deadpool Has Ever Faced

12
420 205
Doctor Doom is listed (or ranked) 12 on the list The Best Villains Deadpool Has Ever Faced

13
400 230
Sabretooth is listed (or ranked) 13 on the list The Best Villains Deadpool Has Ever Faced

14
350 266
BULLSEYE is listed (or ranked) 14 on the list The Best Villains Deadpool Has Ever Faced

15
309 233
Crossbones is listed (or ranked) 15 on the list The Best Villains Deadpool Has Ever Faced

16
184 126
Black Panther is listed (or ranked) 16 on the list The Best Villains Deadpool Has Ever Faced
Benjaminjeune added

17
281 245
Flash Thompson is listed (or ranked) 17 on the list The Best Villains Deadpool Has Ever Faced

18
259 230
Sentinel is listed (or ranked) 18 on the list The Best Villains Deadpool Has Ever Faced

19
99 47
Ajax is listed (or ranked) 19 on the list The Best Villains Deadpool Has Ever Faced
Tyler Gammon added

20
250 223
Green Goblin is listed (or ranked) 20 on the list The Best Villains Deadpool Has Ever Faced
Marvel 1602

21
234 224
Typhoid Mary is listed (or ranked) 21 on the list The Best Villains Deadpool Has Ever Faced

22
237 239
Daken is listed (or ranked) 22 on the list The Best Villains Deadpool Has Ever Faced

23
193 226
Black Mamba is listed (or ranked) 23 on the list The Best Villains Deadpool Has Ever Faced

24
182 214
Madcap is listed (or ranked) 24 on the list The Best Villains Deadpool Has Ever Faced

25
193 239
Vertigo is listed (or ranked) 25 on the list The Best Villains Deadpool Has Ever Faced