Total Nerd The Best Villains Deadpool Has Ever Faced  

Ranker Comics
24.8k votes 2.9k voters 321.5k views 54 items

List Rules Vote up all your favorite villains that you love to see Deadpool go at it with! No heroes!

The Merc with a Mouth, or Deadpool, was created in 1991 by writer Fabian Nicieza and comic illustrator Rob Liefeld. Though Deadpool walks the line of being a villain himself, he's also fought some of the nastiest evil guys around to help save the planet and humankind... when the price is right, anyway. This anti-hero may not always feel the urge to save the day, he still displays an impressive rogue gallery, and we're here to show it to you.
 
We've listed all of Deadpool's greatest enemies on here. Who do you think is the best villain this comic book hero's ever encountered? Do you enjoy the rivalry between Deadpool and Madcap, or do you hold Death in a special place in your heart? 
Make sure to vote up all your favorite Deadpool villains, and vote down the ones you despise. Don't see the villain you love to hate on this list? Be sure to add them!

1
1,465 254
Carnage is listed (or ranked) 1 on the list The Best Villains Deadpool Has Ever Faced

2
1,064 306
Deathstroke is listed (or ranked) 2 on the list The Best Villains Deadpool Has Ever Faced

3
836 259
Evil Deadpool is listed (or ranked) 3 on the list The Best Villains Deadpool Has Ever Faced
Evil Deadpool

4
709 227
Apocalypse is listed (or ranked) 4 on the list The Best Villains Deadpool Has Ever Faced

5
770 285
Taskmaster is listed (or ranked) 5 on the list The Best Villains Deadpool Has Ever Faced

6
598 232
Death is listed (or ranked) 6 on the list The Best Villains Deadpool Has Ever Faced

7
530 229
Red Hulk is listed (or ranked) 7 on the list The Best Villains Deadpool Has Ever Faced

8
497 237
Magneto is listed (or ranked) 8 on the list The Best Villains Deadpool Has Ever Faced

9
415 197
Juggernaut is listed (or ranked) 9 on the list The Best Villains Deadpool Has Ever Faced

10
437 218
Mister Sinister is listed (or ranked) 10 on the list The Best Villains Deadpool Has Ever Faced

11
428 214
Loki is listed (or ranked) 11 on the list The Best Villains Deadpool Has Ever Faced

12
384 194
Doctor Doom is listed (or ranked) 12 on the list The Best Villains Deadpool Has Ever Faced

13
371 217
Sabretooth is listed (or ranked) 13 on the list The Best Villains Deadpool Has Ever Faced

14
285 221
Crossbones is listed (or ranked) 14 on the list The Best Villains Deadpool Has Ever Faced

69 Hilarious Deadpool Comics Moments

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318 256
BULLSEYE is listed (or ranked) 15 on the list The Best Villains Deadpool Has Ever Faced

16
269 221
Flash Thompson is listed (or ranked) 16 on the list The Best Villains Deadpool Has Ever Faced

17
162 110
Black Panther is listed (or ranked) 17 on the list The Best Villains Deadpool Has Ever Faced
Benjaminjeune added Black Panther

18
229 209
Green Goblin is listed (or ranked) 18 on the list The Best Villains Deadpool Has Ever Faced
Green Goblin Marvel 1602

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234 220
Sentinel is listed (or ranked) 19 on the list The Best Villains Deadpool Has Ever Faced

20
228 220
Daken is listed (or ranked) 20 on the list The Best Villains Deadpool Has Ever Faced

21
210 212
Typhoid Mary is listed (or ranked) 21 on the list The Best Villains Deadpool Has Ever Faced

The Worst Marvel Movies of All Time

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69 38
Ajax is listed (or ranked) 22 on the list The Best Villains Deadpool Has Ever Faced
Tyler Gammon added Ajax

23
182 205
Black Mamba is listed (or ranked) 23 on the list The Best Villains Deadpool Has Ever Faced

24
182 222
Vertigo is listed (or ranked) 24 on the list The Best Villains Deadpool Has Ever Faced

25
163 201
Madcap is listed (or ranked) 25 on the list The Best Villains Deadpool Has Ever Faced

26
161 210
Blob is listed (or ranked) 26 on the list The Best Villains Deadpool Has Ever Faced

27
169 225
Dr. Otto Octavius is listed (or ranked) 27 on the list The Best Villains Deadpool Has Ever Faced

28
156 228
T-Ray is listed (or ranked) 28 on the list The Best Villains Deadpool Has Ever Faced

The Best Interpretations & Versions of Deadpool

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140 206
Tombstone is listed (or ranked) 29 on the list The Best Villains Deadpool Has Ever Faced

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123 180
Beyonder is listed (or ranked) 30 on the list The Best Villains Deadpool Has Ever Faced

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82 128
Man-Thing is listed (or ranked) 31 on the list The Best Villains Deadpool Has Ever Faced
Tim Cecil added Man-Thing

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117 197
Black Tom Cassidy is listed (or ranked) 32 on the list The Best Villains Deadpool Has Ever Faced

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117 197
Sauron is listed (or ranked) 33 on the list The Best Villains Deadpool Has Ever Faced

34
100 168
Shriek is listed (or ranked) 34 on the list The Best Villains Deadpool Has Ever Faced

35
108 189
Ghost is listed (or ranked) 35 on the list The Best Villains Deadpool Has Ever Faced

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92 174
Arcade is listed (or ranked) 36 on the list The Best Villains Deadpool Has Ever Faced

37
102 194
Mister X is listed (or ranked) 37 on the list The Best Villains Deadpool Has Ever Faced

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16 34
Slayback is listed (or ranked) 38 on the list The Best Villains Deadpool Has Ever Faced
Freddyjason added Slayback

39
86 171
Doctor Bong is listed (or ranked) 39 on the list The Best Villains Deadpool Has Ever Faced

40
81 169
Tiger Shark is listed (or ranked) 40 on the list The Best Villains Deadpool Has Ever Faced

41
84 181
Blockbuster is listed (or ranked) 41 on the list The Best Villains Deadpool Has Ever Faced

42
76 178
Arclight is listed (or ranked) 42 on the list The Best Villains Deadpool Has Ever Faced

Ranking Every Deadpool in the Comics

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72 170
Headsman is listed (or ranked) 43 on the list The Best Villains Deadpool Has Ever Faced

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71 168
Black Talon is listed (or ranked) 44 on the list The Best Villains Deadpool Has Ever Faced

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68 164
Bulldozer is listed (or ranked) 45 on the list The Best Villains Deadpool Has Ever Faced

46
68 165
Constrictor is listed (or ranked) 46 on the list The Best Villains Deadpool Has Ever Faced

47
66 163
Batroc the Leaper is listed (or ranked) 47 on the list The Best Villains Deadpool Has Ever Faced

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63 157
Wrecker is listed (or ranked) 48 on the list The Best Villains Deadpool Has Ever Faced

49
62 158
Piledriver is listed (or ranked) 49 on the list The Best Villains Deadpool Has Ever Faced

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58 151
Thunderball is listed (or ranked) 50 on the list The Best Villains Deadpool Has Ever Faced