Total Nerd The Best Villains Deadpool Has Ever Faced  

Ranker Comics
22.9k votes 2.7k voters 317.8k views 54 items

List Rules Vote up all your favorite villains that you love to see Deadpool go at it with! No heroes!

The Merc with a Mouth, or Deadpool, was created in 1991 by writer Fabian Nicieza and comic illustrator Rob Liefeld. Though Deadpool walks the line of being a villain himself, he's also fought some of the nastiest evil guys around to help save the planet and humankind... when the price is right, anyway. This anti-hero may not always feel the urge to save the day, he still displays an impressive rogue gallery, and we're here to show it to you.
 
We've listed all of Deadpool's greatest enemies on here. Who do you think is the best villain this comic book hero's ever encountered? Do you enjoy the rivalry between Deadpool and Madcap, or do you hold Death in a special place in your heart? 
Make sure to vote up all your favorite Deadpool villains, and vote down the ones you despise. Don't see the villain you love to hate on this list? Be sure to add them!
list ordered by

1
1,364 224
Carnage is listed (or ranked) 1 on the list The Best Villains Deadpool Has Ever Faced

2
984 280
Deathstroke is listed (or ranked) 2 on the list The Best Villains Deadpool Has Ever Faced

3
757 234
Evil Deadpool is listed (or ranked) 3 on the list The Best Villains Deadpool Has Ever Faced
Evil Deadpool

4
656 211
Apocalypse is listed (or ranked) 4 on the list The Best Villains Deadpool Has Ever Faced

5
719 263
Taskmaster is listed (or ranked) 5 on the list The Best Villains Deadpool Has Ever Faced

6
545 207
Death is listed (or ranked) 6 on the list The Best Villains Deadpool Has Ever Faced

7
486 205
Red Hulk is listed (or ranked) 7 on the list The Best Villains Deadpool Has Ever Faced

8
456 213
Magneto is listed (or ranked) 8 on the list The Best Villains Deadpool Has Ever Faced

9
408 199
Mister Sinister is listed (or ranked) 9 on the list The Best Villains Deadpool Has Ever Faced

10
392 197
Loki is listed (or ranked) 10 on the list The Best Villains Deadpool Has Ever Faced

11
369 186
Juggernaut is listed (or ranked) 11 on the list The Best Villains Deadpool Has Ever Faced

12
352 180
Doctor Doom is listed (or ranked) 12 on the list The Best Villains Deadpool Has Ever Faced

13
349 196
Sabretooth is listed (or ranked) 13 on the list The Best Villains Deadpool Has Ever Faced

14
299 233
BULLSEYE is listed (or ranked) 14 on the list The Best Villains Deadpool Has Ever Faced

15 Actors Who Hate Why They're Famous

15
260 206
Crossbones is listed (or ranked) 15 on the list The Best Villains Deadpool Has Ever Faced

16
140 90
Black Panther is listed (or ranked) 16 on the list The Best Villains Deadpool Has Ever Faced
Benjaminjeune added Black Panther

17
246 210
Flash Thompson is listed (or ranked) 17 on the list The Best Villains Deadpool Has Ever Faced

18
223 199
Sentinel is listed (or ranked) 18 on the list The Best Villains Deadpool Has Ever Faced

19
217 202
Daken is listed (or ranked) 19 on the list The Best Villains Deadpool Has Ever Faced

20
210 194
Green Goblin is listed (or ranked) 20 on the list The Best Villains Deadpool Has Ever Faced
Green Goblin Marvel 1602

21
198 193
Typhoid Mary is listed (or ranked) 21 on the list The Best Villains Deadpool Has Ever Faced

Deadpool Photobombs 20 Classic Marvel Comic Book Covers

22
47 28
Ajax is listed (or ranked) 22 on the list The Best Villains Deadpool Has Ever Faced
Tyler Gammon added Ajax

23
164 193
Black Mamba is listed (or ranked) 23 on the list The Best Villains Deadpool Has Ever Faced

24
169 205
Vertigo is listed (or ranked) 24 on the list The Best Villains Deadpool Has Ever Faced

25
160 205
Dr. Otto Octavius is listed (or ranked) 25 on the list The Best Villains Deadpool Has Ever Faced

26
149 192
Blob is listed (or ranked) 26 on the list The Best Villains Deadpool Has Ever Faced

27
143 186
Madcap is listed (or ranked) 27 on the list The Best Villains Deadpool Has Ever Faced

28
148 209
T-Ray is listed (or ranked) 28 on the list The Best Villains Deadpool Has Ever Faced

The Best Insults from Deadpool

29
132 187
Tombstone is listed (or ranked) 29 on the list The Best Villains Deadpool Has Ever Faced

30
112 161
Beyonder is listed (or ranked) 30 on the list The Best Villains Deadpool Has Ever Faced

31
77 110
Man-Thing is listed (or ranked) 31 on the list The Best Villains Deadpool Has Ever Faced
Tim Cecil added Man-Thing

32
109 180
Sauron is listed (or ranked) 32 on the list The Best Villains Deadpool Has Ever Faced

33
92 151
Shriek is listed (or ranked) 33 on the list The Best Villains Deadpool Has Ever Faced

34
107 183
Black Tom Cassidy is listed (or ranked) 34 on the list The Best Villains Deadpool Has Ever Faced

35
100 176
Ghost is listed (or ranked) 35 on the list The Best Villains Deadpool Has Ever Faced

The Best Members of the Justice League and JLA

36
97 180
Mister X is listed (or ranked) 36 on the list The Best Villains Deadpool Has Ever Faced

37
10 21
Slayback is listed (or ranked) 37 on the list The Best Villains Deadpool Has Ever Faced
Freddyjason added Slayback

38
85 161
Arcade is listed (or ranked) 38 on the list The Best Villains Deadpool Has Ever Faced

39
80 157
Doctor Bong is listed (or ranked) 39 on the list The Best Villains Deadpool Has Ever Faced

40
76 155
Tiger Shark is listed (or ranked) 40 on the list The Best Villains Deadpool Has Ever Faced

41
79 166
Blockbuster is listed (or ranked) 41 on the list The Best Villains Deadpool Has Ever Faced

42
73 165
Arclight is listed (or ranked) 42 on the list The Best Villains Deadpool Has Ever Faced

What Has Iron Man Been Doing Leading Up To 'Avengers: Infinity War'?

43
68 158
Headsman is listed (or ranked) 43 on the list The Best Villains Deadpool Has Ever Faced

44
67 156
Black Talon is listed (or ranked) 44 on the list The Best Villains Deadpool Has Ever Faced

45
65 152
Constrictor is listed (or ranked) 45 on the list The Best Villains Deadpool Has Ever Faced

46
65 152
Bulldozer is listed (or ranked) 46 on the list The Best Villains Deadpool Has Ever Faced

47
60 144
Wrecker is listed (or ranked) 47 on the list The Best Villains Deadpool Has Ever Faced

48
63 152
Batroc the Leaper is listed (or ranked) 48 on the list The Best Villains Deadpool Has Ever Faced

49
56 139
Thunderball is listed (or ranked) 49 on the list The Best Villains Deadpool Has Ever Faced

50
59 148
Piledriver is listed (or ranked) 50 on the list The Best Villains Deadpool Has Ever Faced