Total Nerd The Best Villains Deadpool Has Ever Faced  

Ranker Comics
25k votes 2.9k voters 322.2k views 54 items

List Rules Vote up all your favorite villains that you love to see Deadpool go at it with! No heroes!

The Merc with a Mouth, or Deadpool, was created in 1991 by writer Fabian Nicieza and comic illustrator Rob Liefeld. Though Deadpool walks the line of being a villain himself, he's also fought some of the nastiest evil guys around to help save the planet and humankind... when the price is right, anyway. This anti-hero may not always feel the urge to save the day, he still displays an impressive rogue gallery, and we're here to show it to you.
 
We've listed all of Deadpool's greatest enemies on here. Who do you think is the best villain this comic book hero's ever encountered? Do you enjoy the rivalry between Deadpool and Madcap, or do you hold Death in a special place in your heart? 
Make sure to vote up all your favorite Deadpool villains, and vote down the ones you despise. Don't see the villain you love to hate on this list? Be sure to add them!

1
1,475 256
Carnage is listed (or ranked) 1 on the list The Best Villains Deadpool Has Ever Faced

2
1,070 311
Deathstroke is listed (or ranked) 2 on the list The Best Villains Deadpool Has Ever Faced

3
843 260
Evil Deadpool is listed (or ranked) 3 on the list The Best Villains Deadpool Has Ever Faced
Evil Deadpool

4
713 230
Apocalypse is listed (or ranked) 4 on the list The Best Villains Deadpool Has Ever Faced

5
777 286
Taskmaster is listed (or ranked) 5 on the list The Best Villains Deadpool Has Ever Faced

6
604 233
Death is listed (or ranked) 6 on the list The Best Villains Deadpool Has Ever Faced

7
534 230
Red Hulk is listed (or ranked) 7 on the list The Best Villains Deadpool Has Ever Faced

8
501 238
Magneto is listed (or ranked) 8 on the list The Best Villains Deadpool Has Ever Faced

9
422 197
Juggernaut is listed (or ranked) 9 on the list The Best Villains Deadpool Has Ever Faced

10
444 218
Mister Sinister is listed (or ranked) 10 on the list The Best Villains Deadpool Has Ever Faced

11
432 215
Loki is listed (or ranked) 11 on the list The Best Villains Deadpool Has Ever Faced

12
389 195
Doctor Doom is listed (or ranked) 12 on the list The Best Villains Deadpool Has Ever Faced

13
375 217
Sabretooth is listed (or ranked) 13 on the list The Best Villains Deadpool Has Ever Faced

14
322 256
BULLSEYE is listed (or ranked) 14 on the list The Best Villains Deadpool Has Ever Faced

15
288 222
Crossbones is listed (or ranked) 15 on the list The Best Villains Deadpool Has Ever Faced

16
272 222
Flash Thompson is listed (or ranked) 16 on the list The Best Villains Deadpool Has Ever Faced

17
166 112
Black Panther is listed (or ranked) 17 on the list The Best Villains Deadpool Has Ever Faced
Benjaminjeune added Black Panther

18
239 220
Sentinel is listed (or ranked) 18 on the list The Best Villains Deadpool Has Ever Faced

19
231 212
Green Goblin is listed (or ranked) 19 on the list The Best Villains Deadpool Has Ever Faced
Green Goblin Marvel 1602

20
231 221
Daken is listed (or ranked) 20 on the list The Best Villains Deadpool Has Ever Faced

21
214 213
Typhoid Mary is listed (or ranked) 21 on the list The Best Villains Deadpool Has Ever Faced

22
73 38
Ajax is listed (or ranked) 22 on the list The Best Villains Deadpool Has Ever Faced
Tyler Gammon added Ajax

23
185 207
Black Mamba is listed (or ranked) 23 on the list The Best Villains Deadpool Has Ever Faced

24
185 223
Vertigo is listed (or ranked) 24 on the list The Best Villains Deadpool Has Ever Faced

25
166 201
Madcap is listed (or ranked) 25 on the list The Best Villains Deadpool Has Ever Faced

26
163 210
Blob is listed (or ranked) 26 on the list The Best Villains Deadpool Has Ever Faced

27
170 226
Dr. Otto Octavius is listed (or ranked) 27 on the list The Best Villains Deadpool Has Ever Faced

28
158 228
T-Ray is listed (or ranked) 28 on the list The Best Villains Deadpool Has Ever Faced

29
141 207
Tombstone is listed (or ranked) 29 on the list The Best Villains Deadpool Has Ever Faced

30
123 181
Beyonder is listed (or ranked) 30 on the list The Best Villains Deadpool Has Ever Faced

31
82 129
Man-Thing is listed (or ranked) 31 on the list The Best Villains Deadpool Has Ever Faced
Tim Cecil added Man-Thing

32
118 198
Sauron is listed (or ranked) 32 on the list The Best Villains Deadpool Has Ever Faced

33
117 198
Black Tom Cassidy is listed (or ranked) 33 on the list The Best Villains Deadpool Has Ever Faced

34
100 169
Shriek is listed (or ranked) 34 on the list The Best Villains Deadpool Has Ever Faced

35
108 190
Ghost is listed (or ranked) 35 on the list The Best Villains Deadpool Has Ever Faced

36
92 175
Arcade is listed (or ranked) 36 on the list The Best Villains Deadpool Has Ever Faced

37
102 195
Mister X is listed (or ranked) 37 on the list The Best Villains Deadpool Has Ever Faced

38
16 35
Slayback is listed (or ranked) 38 on the list The Best Villains Deadpool Has Ever Faced
Freddyjason added Slayback

39
86 172
Doctor Bong is listed (or ranked) 39 on the list The Best Villains Deadpool Has Ever Faced

40
82 170
Tiger Shark is listed (or ranked) 40 on the list The Best Villains Deadpool Has Ever Faced

41
84 182
Blockbuster is listed (or ranked) 41 on the list The Best Villains Deadpool Has Ever Faced

42
72 168
Black Talon is listed (or ranked) 42 on the list The Best Villains Deadpool Has Ever Faced

43
76 179
Arclight is listed (or ranked) 43 on the list The Best Villains Deadpool Has Ever Faced

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72 171
Headsman is listed (or ranked) 44 on the list The Best Villains Deadpool Has Ever Faced

45
68 165
Bulldozer is listed (or ranked) 45 on the list The Best Villains Deadpool Has Ever Faced

46
68 166
Constrictor is listed (or ranked) 46 on the list The Best Villains Deadpool Has Ever Faced

47
66 164
Batroc the Leaper is listed (or ranked) 47 on the list The Best Villains Deadpool Has Ever Faced

48
63 158
Wrecker is listed (or ranked) 48 on the list The Best Villains Deadpool Has Ever Faced

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62 159
Piledriver is listed (or ranked) 49 on the list The Best Villains Deadpool Has Ever Faced

50
58 152
Thunderball is listed (or ranked) 50 on the list The Best Villains Deadpool Has Ever Faced