Total Nerd The Best Villains Deadpool Has Ever Faced  

Ranker Comics
25.4k votes 3k voters 323.9k views 54 items

List Rules Vote up all your favorite villains that you love to see Deadpool go at it with! No heroes!

The Merc with a Mouth, or Deadpool, was created in 1991 by writer Fabian Nicieza and comic illustrator Rob Liefeld. Though Deadpool walks the line of being a villain himself, he's also fought some of the nastiest evil guys around to help save the planet and humankind... when the price is right, anyway. This anti-hero may not always feel the urge to save the day, he still displays an impressive rogue gallery, and we're here to show it to you.
 
We've listed all of Deadpool's greatest enemies on here. Who do you think is the best villain this comic book hero's ever encountered? Do you enjoy the rivalry between Deadpool and Madcap, or do you hold Death in a special place in your heart? 
Make sure to vote up all your favorite Deadpool villains, and vote down the ones you despise. Don't see the villain you love to hate on this list? Be sure to add them!
list ordered by

1
1,500 263
Carnage is listed (or ranked) 1 on the list The Best Villains Deadpool Has Ever Faced

2
1,090 317
Deathstroke is listed (or ranked) 2 on the list The Best Villains Deadpool Has Ever Faced

3
863 264
Evil Deadpool is listed (or ranked) 3 on the list The Best Villains Deadpool Has Ever Faced
Evil Deadpool

4
728 234
Apocalypse is listed (or ranked) 4 on the list The Best Villains Deadpool Has Ever Faced

5
792 290
Taskmaster is listed (or ranked) 5 on the list The Best Villains Deadpool Has Ever Faced

6
613 241
Death is listed (or ranked) 6 on the list The Best Villains Deadpool Has Ever Faced

7
545 234
Red Hulk is listed (or ranked) 7 on the list The Best Villains Deadpool Has Ever Faced

8
514 239
Magneto is listed (or ranked) 8 on the list The Best Villains Deadpool Has Ever Faced

9
436 199
Juggernaut is listed (or ranked) 9 on the list The Best Villains Deadpool Has Ever Faced

10
452 221
Mister Sinister is listed (or ranked) 10 on the list The Best Villains Deadpool Has Ever Faced

11
442 219
Loki is listed (or ranked) 11 on the list The Best Villains Deadpool Has Ever Faced

12
398 197
Doctor Doom is listed (or ranked) 12 on the list The Best Villains Deadpool Has Ever Faced

13
383 220
Sabretooth is listed (or ranked) 13 on the list The Best Villains Deadpool Has Ever Faced

14
294 224
Crossbones is listed (or ranked) 14 on the list The Best Villains Deadpool Has Ever Faced

15
328 260
BULLSEYE is listed (or ranked) 15 on the list The Best Villains Deadpool Has Ever Faced

16
275 228
Flash Thompson is listed (or ranked) 16 on the list The Best Villains Deadpool Has Ever Faced

17
170 116
Black Panther is listed (or ranked) 17 on the list The Best Villains Deadpool Has Ever Faced
Benjaminjeune added

18
245 222
Sentinel is listed (or ranked) 18 on the list The Best Villains Deadpool Has Ever Faced

19
236 215
Green Goblin is listed (or ranked) 19 on the list The Best Villains Deadpool Has Ever Faced
Marvel 1602

20
233 225
Daken is listed (or ranked) 20 on the list The Best Villains Deadpool Has Ever Faced

21
77 41
Ajax is listed (or ranked) 21 on the list The Best Villains Deadpool Has Ever Faced
Tyler Gammon added

22
217 218
Typhoid Mary is listed (or ranked) 22 on the list The Best Villains Deadpool Has Ever Faced

23
186 212
Black Mamba is listed (or ranked) 23 on the list The Best Villains Deadpool Has Ever Faced

24
188 227
Vertigo is listed (or ranked) 24 on the list The Best Villains Deadpool Has Ever Faced

25
168 206
Madcap is listed (or ranked) 25 on the list The Best Villains Deadpool Has Ever Faced

26
165 214
Blob is listed (or ranked) 26 on the list The Best Villains Deadpool Has Ever Faced

27
173 228
Dr. Otto Octavius is listed (or ranked) 27 on the list The Best Villains Deadpool Has Ever Faced

28
160 231
T-Ray is listed (or ranked) 28 on the list The Best Villains Deadpool Has Ever Faced

29
125 183
Beyonder is listed (or ranked) 29 on the list The Best Villains Deadpool Has Ever Faced

30
142 211
Tombstone is listed (or ranked) 30 on the list The Best Villains Deadpool Has Ever Faced

31
83 133
Man-Thing is listed (or ranked) 31 on the list The Best Villains Deadpool Has Ever Faced
Tim Cecil added

32
119 201
Sauron is listed (or ranked) 32 on the list The Best Villains Deadpool Has Ever Faced

33
119 203
Black Tom Cassidy is listed (or ranked) 33 on the list The Best Villains Deadpool Has Ever Faced

34
101 172
Shriek is listed (or ranked) 34 on the list The Best Villains Deadpool Has Ever Faced

35
111 191
Ghost is listed (or ranked) 35 on the list The Best Villains Deadpool Has Ever Faced

36
93 177
Arcade is listed (or ranked) 36 on the list The Best Villains Deadpool Has Ever Faced

37
104 199
Mister X is listed (or ranked) 37 on the list The Best Villains Deadpool Has Ever Faced

38
86 175
Doctor Bong is listed (or ranked) 38 on the list The Best Villains Deadpool Has Ever Faced

39
16 38
Slayback is listed (or ranked) 39 on the list The Best Villains Deadpool Has Ever Faced
Freddyjason added Slayback

40
82 174
Tiger Shark is listed (or ranked) 40 on the list The Best Villains Deadpool Has Ever Faced

41
84 185
Blockbuster is listed (or ranked) 41 on the list The Best Villains Deadpool Has Ever Faced

42
72 171
Black Talon is listed (or ranked) 42 on the list The Best Villains Deadpool Has Ever Faced

43
69 167
Bulldozer is listed (or ranked) 43 on the list The Best Villains Deadpool Has Ever Faced

44
76 182
Arclight is listed (or ranked) 44 on the list The Best Villains Deadpool Has Ever Faced

45
72 174
Headsman is listed (or ranked) 45 on the list The Best Villains Deadpool Has Ever Faced

46
69 168
Constrictor is listed (or ranked) 46 on the list The Best Villains Deadpool Has Ever Faced

47
65 160
Wrecker is listed (or ranked) 47 on the list The Best Villains Deadpool Has Ever Faced

48
66 167
Batroc the Leaper is listed (or ranked) 48 on the list The Best Villains Deadpool Has Ever Faced

49
62 161
Piledriver is listed (or ranked) 49 on the list The Best Villains Deadpool Has Ever Faced

50
58 154
Thunderball is listed (or ranked) 50 on the list The Best Villains Deadpool Has Ever Faced