Total Nerd The Best Villains Deadpool Has Ever Faced  

Ranker Comics
23.9k votes 2.8k voters 320k views 54 items

List Rules Vote up all your favorite villains that you love to see Deadpool go at it with! No heroes!

The Merc with a Mouth, or Deadpool, was created in 1991 by writer Fabian Nicieza and comic illustrator Rob Liefeld. Though Deadpool walks the line of being a villain himself, he's also fought some of the nastiest evil guys around to help save the planet and humankind... when the price is right, anyway. This anti-hero may not always feel the urge to save the day, he still displays an impressive rogue gallery, and we're here to show it to you.
 
We've listed all of Deadpool's greatest enemies on here. Who do you think is the best villain this comic book hero's ever encountered? Do you enjoy the rivalry between Deadpool and Madcap, or do you hold Death in a special place in your heart? 
Make sure to vote up all your favorite Deadpool villains, and vote down the ones you despise. Don't see the villain you love to hate on this list? Be sure to add them!
list ordered by

1
1,430 245
Carnage is listed (or ranked) 1 on the list The Best Villains Deadpool Has Ever Faced

2
1,037 295
Deathstroke is listed (or ranked) 2 on the list The Best Villains Deadpool Has Ever Faced

3
810 248
Evil Deadpool is listed (or ranked) 3 on the list The Best Villains Deadpool Has Ever Faced
Evil Deadpool

4
694 219
Apocalypse is listed (or ranked) 4 on the list The Best Villains Deadpool Has Ever Faced

5
751 275
Taskmaster is listed (or ranked) 5 on the list The Best Villains Deadpool Has Ever Faced

6
580 222
Death is listed (or ranked) 6 on the list The Best Villains Deadpool Has Ever Faced

7
514 219
Red Hulk is listed (or ranked) 7 on the list The Best Villains Deadpool Has Ever Faced

8
486 224
Magneto is listed (or ranked) 8 on the list The Best Villains Deadpool Has Ever Faced

9
425 209
Mister Sinister is listed (or ranked) 9 on the list The Best Villains Deadpool Has Ever Faced

10
413 207
Loki is listed (or ranked) 10 on the list The Best Villains Deadpool Has Ever Faced

11
394 193
Juggernaut is listed (or ranked) 11 on the list The Best Villains Deadpool Has Ever Faced

12
372 186
Doctor Doom is listed (or ranked) 12 on the list The Best Villains Deadpool Has Ever Faced

13
363 204
Sabretooth is listed (or ranked) 13 on the list The Best Villains Deadpool Has Ever Faced

14
308 246
BULLSEYE is listed (or ranked) 14 on the list The Best Villains Deadpool Has Ever Faced

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15
273 213
Crossbones is listed (or ranked) 15 on the list The Best Villains Deadpool Has Ever Faced

16
258 214
Flash Thompson is listed (or ranked) 16 on the list The Best Villains Deadpool Has Ever Faced

17
149 102
Black Panther is listed (or ranked) 17 on the list The Best Villains Deadpool Has Ever Faced
Benjaminjeune added Black Panther

18
230 208
Sentinel is listed (or ranked) 18 on the list The Best Villains Deadpool Has Ever Faced

19
221 200
Green Goblin is listed (or ranked) 19 on the list The Best Villains Deadpool Has Ever Faced
Green Goblin Marvel 1602

20
223 208
Daken is listed (or ranked) 20 on the list The Best Villains Deadpool Has Ever Faced

21
204 202
Typhoid Mary is listed (or ranked) 21 on the list The Best Villains Deadpool Has Ever Faced

Deadpool Photobombs 20 Classic Marvel Comic Book Covers

22
56 33
Ajax is listed (or ranked) 22 on the list The Best Villains Deadpool Has Ever Faced
Tyler Gammon added Ajax

23
170 199
Black Mamba is listed (or ranked) 23 on the list The Best Villains Deadpool Has Ever Faced

24
176 212
Vertigo is listed (or ranked) 24 on the list The Best Villains Deadpool Has Ever Faced

25
156 190
Madcap is listed (or ranked) 25 on the list The Best Villains Deadpool Has Ever Faced

26
165 212
Dr. Otto Octavius is listed (or ranked) 26 on the list The Best Villains Deadpool Has Ever Faced

27
155 199
Blob is listed (or ranked) 27 on the list The Best Villains Deadpool Has Ever Faced

28
152 217
T-Ray is listed (or ranked) 28 on the list The Best Villains Deadpool Has Ever Faced

The Best Insults from Deadpool

29
137 194
Tombstone is listed (or ranked) 29 on the list The Best Villains Deadpool Has Ever Faced

30
119 167
Beyonder is listed (or ranked) 30 on the list The Best Villains Deadpool Has Ever Faced

31
78 118
Man-Thing is listed (or ranked) 31 on the list The Best Villains Deadpool Has Ever Faced
Tim Cecil added Man-Thing

32
96 157
Shriek is listed (or ranked) 32 on the list The Best Villains Deadpool Has Ever Faced

33
113 187
Black Tom Cassidy is listed (or ranked) 33 on the list The Best Villains Deadpool Has Ever Faced

34
112 187
Sauron is listed (or ranked) 34 on the list The Best Villains Deadpool Has Ever Faced

35
104 181
Ghost is listed (or ranked) 35 on the list The Best Villains Deadpool Has Ever Faced

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36
100 185
Mister X is listed (or ranked) 36 on the list The Best Villains Deadpool Has Ever Faced

37
88 167
Arcade is listed (or ranked) 37 on the list The Best Villains Deadpool Has Ever Faced

38
84 162
Doctor Bong is listed (or ranked) 38 on the list The Best Villains Deadpool Has Ever Faced

39
12 28
Slayback is listed (or ranked) 39 on the list The Best Villains Deadpool Has Ever Faced
Freddyjason added Slayback

40
80 160
Tiger Shark is listed (or ranked) 40 on the list The Best Villains Deadpool Has Ever Faced

41
82 172
Blockbuster is listed (or ranked) 41 on the list The Best Villains Deadpool Has Ever Faced

42
75 170
Arclight is listed (or ranked) 42 on the list The Best Villains Deadpool Has Ever Faced

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43
71 163
Headsman is listed (or ranked) 43 on the list The Best Villains Deadpool Has Ever Faced

44
70 161
Black Talon is listed (or ranked) 44 on the list The Best Villains Deadpool Has Ever Faced

45
67 157
Bulldozer is listed (or ranked) 45 on the list The Best Villains Deadpool Has Ever Faced

46
62 149
Wrecker is listed (or ranked) 46 on the list The Best Villains Deadpool Has Ever Faced

47
66 158
Constrictor is listed (or ranked) 47 on the list The Best Villains Deadpool Has Ever Faced

48
64 156
Batroc the Leaper is listed (or ranked) 48 on the list The Best Villains Deadpool Has Ever Faced

49
61 151
Piledriver is listed (or ranked) 49 on the list The Best Villains Deadpool Has Ever Faced

50
57 143
Thunderball is listed (or ranked) 50 on the list The Best Villains Deadpool Has Ever Faced