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The 20 Greatest Female Anime Villains of All Time

Updated January 21, 2020 28.6k votes 4.8k voters 96.9k views20 items

Not all women are nice - actually, some of them are straight up evil. The best female anime villains are great for the same reasons that villains of other genders are: they have nefarious plans, interesting backstories, and are either so evil that seeing them get defeated is a joy, or so fascinating that you're almost kind of rooting for them despite their alignment. 

Among the best are Lust from Fullmetal Alchemist, Annie Leonhardt of Attack On Titan, Himiko Toga of My Hero Academia, Balalaika of Black Lagoon and more. Which villainous lady do you love to hate?

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  • Photo: White Fox

    As a high-ranking general of the Empire, Esdeath takes her job seriously. If you're unlucky enough to be one of her enemies, prepare for utter sadism - but if you're one of her subordinates, she'll treat you very, very well.

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  • 2

    Lust - 'Fullmetal Alchemist: Brotherhood'

    Lust is one of the homunculi who dedicates their lives to serving Father. Unlike the other homunculi, who exhibit the sin that they're named for, Lust prefers inspiring lust in others and using it to her advantage.

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  • 3

    Isabella - 'The Promised Neverland'

    Isabella is the seemingly kindly caretaker of Gracefield House, but she's secretly selling the orphans to demons to use as meat. 

    It's hard to blame her, since this was one of the only ways she could avoid the same fate herself, but nevertheless she still caused some serious damage.

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  • 4

    Junko Enoshima - 'Danganronpa'

    Photo: Lerche

    Unlike some villains who are in it for personal gain, Junko Enoshima just wants to fill the world with her favorite thing, despair. She's the mastermind behind the Killing Games, and one of the most sadistic villains in anime history. 

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