The 21 Best Female Characters From Isekai Anime

Isekai can sometimes feel like a male-dominated genre, but that doesn't mean there aren't some amazing women and girls throughout the genre. Let's make some noise for the best isekai girls!

Some of the best female isekai anime characters are protagonists in their own right, as is the case for Miaka Yuki of Fushigi Yugi, Hitomi Kanzaki of Escaflowne, and more recently, Motosu Urano of Ascendence of a Bookworm. Other great anime women may not be the main characters, but they still have important roles to play. After all, what would Rising of the Shield Hero be without Raphtalia and Filo? Many of these characters are capable fighters who can go toe-to-toe with the male cast members. Others don't battle but still have valuable skills to bring to the table. 

Vote up all of your favorite isekai ladies!


  • 1
    6,177 VOTES

    Raphtalia - 'The Rising of the Shield Hero'

    Raphtalia was once a slave who led a life of isolation and misery. After teaming up with Naofumi, she lives purposefully and contentedly as his 'sword.'

  • 2
    4,945 VOTES

    Rem - 'Re:Zero'

    Rem - 'Re:Zero'
    Photo: White Fox

    Rem works alongside her twin sister Ram as a maid to Roswaal L Mathers. She's a kind and loyal person who is deeply in love with Subaru, and whose feelings toward her sister Ram are influenced by powerful guilt.

  • 3
    4,473 VOTES

    Albedo - 'Overlord'

    Albedo - 'Overlord'
    Photo: Madhouse

    Albedo is a succubus who is a member of Ainz Ooal Gown's guild. She's hotheaded and quick to destroy things, but is kept in check by her leader's commands.

  • 4
    4,698 VOTES

    Megumin - 'KonoSuba'

    Megumin is the Arch Wizard of the Crimson Demon Clan, but despite her actual magical abilities, she still has a bad case of chuunibyo - meaning, she wants to believe that she's even more magical and impressive than she already is. She lacks control over her powers and often uses them recklessly to show off, but she's hard not to love for her enthusiasm.