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The 21 Best Female Characters From Isekai Anime

Isekai can sometimes feel like a male-dominated genre, but that doesn't mean there aren't some amazing women and girls throughout the genre. Let's make some noise for the best isekai girls!

Some of the best female isekai anime characters are protagonists in their own right, as is the case for Miaka Yuki of Fushigi Yugi, Hitomi Kanzaki of Escaflowne, and more recently, Motosu Urano of Ascendence of a Bookworm. Other great anime women may not be the main characters, but they still have important roles to play. After all, what would Rising of the Shield Hero be without Raphtalia and Filo? Many of these characters are capable fighters who can go toe-to-toe with the male cast members. Others don't battle but still have valuable skills to bring to the table. 

Vote up all of your favorite isekai ladies!

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  • 1
    5,975 VOTES

    Raphtalia - 'The Rising of the Shield Hero'

    Raphtalia was once a slave who led a life of isolation and misery. After teaming up with Naofumi, she lives purposefully and contentedly as his 'sword.'

    5,975 votes
  • 2
    4,780 VOTES

    Rem - 'Re:Zero'

    Rem - 'Re:Zero'
    Photo: White Fox

    Rem works alongside her twin sister Ram as a maid to Roswaal L Mathers. She's a kind and loyal person who is deeply in love with Subaru, and whose feelings toward her sister Ram are influenced by powerful guilt.

    4,780 votes
  • 3
    4,338 VOTES

    Albedo - 'Overlord'

    Albedo - 'Overlord'
    Photo: Madhouse

    Albedo is a succubus who is a member of Ainz Ooal Gown's guild. She's hotheaded and quick to destroy things, but is kept in check by her leader's commands.

    4,338 votes
  • 4
    4,549 VOTES

    Megumin - 'KonoSuba'

    Megumin is the Arch Wizard of the Crimson Demon Clan, but despite her actual magical abilities, she still has a bad case of chuunibyo - meaning, she wants to believe that she's even more magical and impressive than she already is. She lacks control over her powers and often uses them recklessly to show off, but she's hard not to love for her enthusiasm. 

    4,549 votes
  • 5
    4,612 VOTES

    Filo - 'The Rising of the Shield Hero'

    Filo is a filolial, a giant bird with a human transformation. She's been traveling with Naofumi and Raphtalia since she was born, and she brings joy and happiness wherever she goes. 

    4,612 votes
  • 6
    3,671 VOTES

    Shizue Izawa - 'That Time I Got Reincarnated As A Slime'

    Shizue Izawa - 'That Time I Got Reincarnated As A Slime'
    Photo: 8bit

    Shizue was transported from Earth to a fantasy world after the 1940's bombing of Tokyo. From there, she continued to have a tough time after a demon named Ifrit was forcibly housed in her body, giving her powers that were hard to control. She ended up bonding with Rimuru, giving him both a mission in life, and a human form. 

    3,671 votes