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The Best Horror Movies About Evil Experiments

Updated September 15, 2020 1.6k votes 323 voters 23.5k views31 items

Horror movies about evil experiments often vary in subject matter from crazy science experiments gone wrong to movies with experiments that go exactly as planned. Sometimes, the experiment is on a human subject, as seen in The Fly or The Human Centipede. Other times, scary movies can be about social experiments, like in the The Belko Experiment. Military and medical experiments can also be the source of a scourge in some of these film. The plot of the film is simple- coworkers in an office are pitted against each other in a kill or be killed situation.

Sometimes the experiments themselves are not evil, but the result is. Morgan is about a scientifically created "human" that loses its mind and begins to kill the scientists that helped create her. Other good scary movies about experiments gone wrong include Re-Animator, Scanners, and From Beyond.

The purpose of this list is to rank the best evil experiment horror movies, so vote up your favorites below, and add to the list if you think the scariest human experiment movie isn't already here.

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  • 1
    The Fly is listed (or ranked) 1 on the list The Best Horror Movies About Evil Experiments
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    The Fly

    Geena Davis, Jeff Goldblum

    Released1986

    Directed byDavid Cronenberg

  • 2
    Frankenstein is listed (or ranked) 2 on the list The Best Horror Movies About Evil Experiments
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    22

    Frankenstein

    Boris Karloff, John Boles

    Released1931

    Directed byJames Whale

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  • 3
    Dark City is listed (or ranked) 3 on the list The Best Horror Movies About Evil Experiments
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    20

    Dark City

    Jennifer Connelly, Kiefer Sutherland

    Released1998

    Directed byAlex Proyas

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  • 4
    Re-Animator is listed (or ranked) 4 on the list The Best Horror Movies About Evil Experiments
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    19

    Re-Animator

    Barbara Crampton, Jeffrey Combs

    Released1985

    Directed byStuart Gordon

  • 5
    The Belko Experiment is listed (or ranked) 5 on the list The Best Horror Movies About Evil Experiments
    71
    38

    The Belko Experiment

    John Gallagher, Jr.

    Directed byGreg McLean

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  • 6
    Splice is listed (or ranked) 6 on the list The Best Horror Movies About Evil Experiments
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    Splice

    Adrien Brody, Sarah Polley

    Released2009

    Directed byVincenzo Natali

  • 7
    Flatliners is listed (or ranked) 7 on the list The Best Horror Movies About Evil Experiments
    59
    29

    Flatliners

    Julia Roberts, Kevin Bacon

    Released1990

    Directed byJoel Schumacher

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  • 8
    Scanners is listed (or ranked) 8 on the list The Best Horror Movies About Evil Experiments
    39
    17

    Scanners

    Michael Ironside, Patrick McGoohan

    Released1981

    Directed byDavid Cronenberg

  • 9
    Firestarter is listed (or ranked) 9 on the list The Best Horror Movies About Evil Experiments
    36
    20

    Firestarter

    Drew Barrymore, Heather Locklear

    Released1984

    Directed byMark L. Lester

  • 10
    Human Experiments is listed (or ranked) 10 on the list The Best Horror Movies About Evil Experiments
    34
    23

    Human Experiments

    Geoffrey Lewis, Lurene Tuttle

    Released1979

    Directed byGregory Goodell

  • 11
    Morgan is listed (or ranked) 11 on the list The Best Horror Movies About Evil Experiments
    38
    34

    Morgan

    Kate Mara, Anya Taylor-Joy

    Released2016

    Directed byLuke Scott

  • 12
    Would You Rather is listed (or ranked) 12 on the list The Best Horror Movies About Evil Experiments
    44
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    Would You Rather

    Sasha Grey, Brittany Snow

    Released2012

    Directed byDavid Guy Levy

  • 13
    Altered States is listed (or ranked) 13 on the list The Best Horror Movies About Evil Experiments
    24
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    Altered States

    Drew Barrymore, William Hurt

    Released1980

    Directed byKen Russell

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  • 14
    The Lazarus Effect is listed (or ranked) 14 on the list The Best Horror Movies About Evil Experiments
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    The Lazarus Effect

    Mark Duplass, Olivia Wilde

    Released2015

    Directed byDavid Gelb

    More 

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  • 15
    From Beyond is listed (or ranked) 15 on the list The Best Horror Movies About Evil Experiments
    26
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    From Beyond

    Barbara Crampton, Jeffrey Combs

    Released1986

    Directed byStuart Gordon

    More From Beyond 

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  • 16
    The Mist is listed (or ranked) 16 on the list The Best Horror Movies About Evil Experiments
    2
    0

    The Mist

    Thomas Jane, Marcia Gay Harden

    Released2007

    Directed byFrank Darabont

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  • 17
    The Island of Dr. Moreau is listed (or ranked) 17 on the list The Best Horror Movies About Evil Experiments
    30
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    The Island of Dr. Moreau

    Marlon Brando, Val Kilmer

    Released1996

    Directed byJohn Frankenheimer, Richard Stanley

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  • 18
    Ex Machina is listed (or ranked) 18 on the list The Best Horror Movies About Evil Experiments
    2
    0

    Ex Machina

    Domhnall Gleeson, Alicia Vikander

    Released2015

    Directed byAlex Garland

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  • 19
    The Experiment is listed (or ranked) 19 on the list The Best Horror Movies About Evil Experiments
    23
    23

    The Experiment

    Fatih Akın, Moritz Bleibtreu

    Released2001

    Directed byOliver Hirschbiegel

  • 20
    Men Behind the Sun is listed (or ranked) 20 on the list The Best Horror Movies About Evil Experiments
    20
    21

    Men Behind the Sun

    Wang Gang, Runsheng Wang

    Released1988

    Directed byMou Tun-fei

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  • 21
    Flatliners is listed (or ranked) 21 on the list The Best Horror Movies About Evil Experiments
    1
    1

    Flatliners

    Ellen Page, Diego Luna

    Directed byNiels Arden Oplev

  • 22
    The Human Centipede (First Seq is listed (or ranked) 22 on the list The Best Horror Movies About Evil Experiments
    41
    51

    The Human Centipede (First Sequence)

    Ashley C. Williams, Dieter Laser

    Released2009

    Directed byTom Six

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  • 23
    The Skin I Live In is listed (or ranked) 23 on the list The Best Horror Movies About Evil Experiments
    14
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    The Skin I Live In

    Antonio Banderas, Blanca Suárez

    Released2011

    Directed byPedro Almodóvar

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  • 24
    The Killing Room is listed (or ranked) 24 on the list The Best Horror Movies About Evil Experiments
    14
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    The Killing Room

    Nick Cannon, Chloë Sevigny

    Released2009

    Directed byJonathan Liebesman

  • 25
    The Banshee Chapter is listed (or ranked) 25 on the list The Best Horror Movies About Evil Experiments
    13
    20

    The Banshee Chapter

    Ted Levine, Katia Winter

    Released2013

    Directed byBlair Erickson

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