films The Best Horror Movies About Virus Outbreaks  

Ranker Film
1.4k votes 194 voters 8.2k views 45 items

There's something in the air, and you definitely don't want to breath it in. Horror movies about viruses and diseases are particularly frightening, because they are among the most plausible situations that could actually happen in real life. This list ranks the scariest movies about virus outbreaks that infect large groups of people.

It can be a bit tricky to distinguish virus outbreak horror movies from zombie films, because often times zombies are birthed from some kind of airborne virus or disease. However, most of the virus horror movies on this list are more about the contagions infecting people than they are the result of the disease. Examples of these films include Viral, Quarantine, and The Happening.

It Follows is probably the best horror movie about a disease. It's kind of tricky to explain the plot if you haven't seen it, so just go ahead and watch the film if it has somehow evaded you up to this point- you definitely won't be disappointed.

list ordered by

1
60 7
28 Days Later is listed (or ranked) 1 on the list The Best Horror Movies About Virus Outbreaks
28 Days Later Cillian Murphy, Christopher Eccleston, Naomie Harris 28 Days Later is a 2002 British post-apocalyptic horror film directed by Danny Boyle. The screenplay was written by Alex Garland. The film stars Cillian Murphy, Naomie Harris, Brendan Gleeson, ...more

2
51 15
28 Weeks Later is listed (or ranked) 2 on the list The Best Horror Movies About Virus Outbreaks
28 Weeks Later Rose Byrne, Idris Elba, Jeremy Renner 28 Weeks Later is a 2007 British-Spanish post-apocalyptic science fiction horror film, structured as a sequel to the 2002 critical and commercial success, 28 Days Later. 28 Weeks Later was ...more

3
37 10
REC is listed (or ranked) 3 on the list The Best Horror Movies About Virus Outbreaks
REC Manuela Velasco, Javier Botet, Ana Isabel Velásquez REC is a 2007 Spanish horror film, co-written and directed by Jaume Balagueró and Paco Plaza. The film was shot in Barcelona, Spain and the title is an abbreviation of the word ...more

4
40 15
Outbreak is listed (or ranked) 4 on the list The Best Horror Movies About Virus Outbreaks
Outbreak Morgan Freeman, Kevin Spacey, Dustin Hoffman Outbreak is a 1995 American medical disaster film directed by Wolfgang Petersen and based on Richard Preston's non-fiction book The Hot Zone. The film stars Dustin Hoffman, Rene Russo, and ...more

5
43 18
I Am Legend is listed (or ranked) 5 on the list The Best Horror Movies About Virus Outbreaks
I Am Legend Will Smith, Emma Thompson, Salli Richardson I Am Legend is a 2007 American post-apocalyptic science fiction horror film directed by Francis Lawrence and starring Will Smith. It is the third feature film adaptation of Richard Matheson's ...more

6
36 13
The Crazies is listed (or ranked) 6 on the list The Best Horror Movies About Virus Outbreaks
The Crazies Danielle Panabaker, Timothy Olyphant, Radha Mitchell The Crazies is a 2010 American horror film directed by Breck Eisner, with a screenplay by Scott Kosar and Ray Wright. The film is a remake of the 1973 film of the same name by George A. Romero, ...more

7
33 12
Resident Evil is listed (or ranked) 7 on the list The Best Horror Movies About Virus Outbreaks
Resident Evil Milla Jovovich, Michelle Rodriguez, Jason Isaacs Resident Evil is a 2002 German-British-French science fiction horror film written and directed by Paul W. S. Anderson. The film stars Milla Jovovich and Michelle Rodriguez. It is the first ...more

8
35 15
Quarantine is listed (or ranked) 8 on the list The Best Horror Movies About Virus Outbreaks
Quarantine Dania Ramirez, Jennifer Carpenter, Doug Jones Quarantine is a 2008 American science fiction horror film directed by John Erick Dowdle and starring Jennifer Carpenter, Jay Hernandez, Columbus Short, Greg Germann, Steve Harris, Dania Ramirez, ...more

9
31 12
Cabin Fever is listed (or ranked) 9 on the list The Best Horror Movies About Virus Outbreaks
Cabin Fever Eli Roth, Cerina Vincent, Jordan Ladd Cabin Fever is a 2002 American black comedy horror film directed by Eli Roth and starring Rider Strong, Jordan Ladd, James DeBello and Giuseppe Andrews. It was produced by Lauren Moews & ...more

10
42 23
World War Z is listed (or ranked) 10 on the list The Best Horror Movies About Virus Outbreaks
World War Z Brad Pitt, Matthew Fox, David Morse World War Z is a 2013 American apocalyptic action horror film directed by Marc Forster. The screenplay by Matthew Michael Carnahan, Drew Goddard, and Damon Lindelof is from a screen story by ...more

11
37 19
It Follows is listed (or ranked) 11 on the list The Best Horror Movies About Virus Outbreaks
It Follows Maika Monroe, Keir Gilchrist, Linda Boston It Follows is a 2014 Horror film written by David Robert Mitchell and directed by David Robert Mitchell.

12
22 10
Resident Evil: Extinction is listed (or ranked) 12 on the list The Best Horror Movies About Virus Outbreaks
Resident Evil: Extinction Milla Jovovich, Ali Larter, Ashanti RESIDENT EVIL: EXTINCTION is again based on the wildly popular video game series and picks up where the last film left off. Alice (Milla Jovovich), now in hiding in the Nevada desert, once again ...more

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22 10
Resident Evil: Retribution is listed (or ranked) 13 on the list The Best Horror Movies About Virus Outbreaks
Resident Evil: Retribution Milla Jovovich, Ali Larter, Michelle Rodriguez Resident Evil: Retribution is a 2012 American-Canadian-German science fiction action horror film written and directed by Paul W. S. Anderson. It is the fifth installment in the Resident Evil ...more

14
21 11
Planet Terror is listed (or ranked) 14 on the list The Best Horror Movies About Virus Outbreaks
Planet Terror Bruce Willis, Rose McGowan, Fergie Planet Terror is a 2007 American action horror science-fiction film directed by Robert Rodriguez, about a group of people attempting to survive an onslaught of zombie-like creatures as they feud ...more

15
24 14
The Stand is listed (or ranked) 15 on the list The Best Horror Movies About Virus Outbreaks
The Stand Stephen King, Rob Lowe, Molly Ringwald The Stand is a 1994 American television miniseries based on the novel of the same name by Stephen King. King also wrote the teleplay, and has a cameo role in the series. It was directed by Mick ...more

16
19 10
Quarantine 2: Terminal is listed (or ranked) 16 on the list The Best Horror Movies About Virus Outbreaks
Quarantine 2: Terminal Mercedes Masöhn, Ignacio Serricchio, Josh Cooke Quarantine 2: Terminal is a 2011 American science fiction horror film and a sequel to the 2008 film, Quarantine. It was written and directed by John Pogue and produced by Marc Brienstock. The ...more

17
19 10
Pontypool is listed (or ranked) 17 on the list The Best Horror Movies About Virus Outbreaks
Pontypool Stephen McHattie, Daniel Fathers, Boyd Banks Pontypool is a 2008 horror film directed by Bruce McDonald and adapted by Tony Burgess from Burgess' novel Pontypool Changes Everything.

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20 11
Resident Evil: Apocalypse is listed (or ranked) 18 on the list The Best Horror Movies About Virus Outbreaks
Resident Evil: Apocalypse Milla Jovovich, Iain Glen, Sienna Guillory Resident Evil: Apocalypse is a 2004 British-Canadian apocalyptic fiction action horror film directed by Alexander Witt, from a screenplay written by producer Paul W. S. Anderson. It is the ...more

19
16 8
Doomsday is listed (or ranked) 19 on the list The Best Horror Movies About Virus Outbreaks
Doomsday Rhona Mitra, Malcolm McDowell, Bob Hoskins Doomsday is a 2008 science fiction action film written and directed by Neil Marshall. The film takes place in the future in Scotland, which has been quarantined because of a deadly virus. When ...more

20
18 10
Dreamcatcher is listed (or ranked) 20 on the list The Best Horror Movies About Virus Outbreaks
Dreamcatcher Morgan Freeman, Timothy Olyphant, Damian Lewis Dreamcatcher is a 2003 science fiction horror film adaptation of Stephen King's novel of the same name. It was directed by Lawrence Kasdan, and co-written by Kasdan and screenwriter William ...more

21
19 11
Afflicted is listed (or ranked) 21 on the list The Best Horror Movies About Virus Outbreaks
Afflicted Zach Gray, Michel Gill, Greg Ng Afflicted is a 2013 Canadian found footage film that was written and directed by Derek Lee and Clif Prowse, and is their feature film directorial debut. It had its world premiere on September 9, ...more

22
15 8
The Omega Man is listed (or ranked) 22 on the list The Best Horror Movies About Virus Outbreaks
The Omega Man Charlton Heston, Anthony Zerbe, Eric Laneuville The Omega Man is a 1971 American science fiction film directed by Boris Sagal and starring Charlton Heston. It was written by John William Corrington and Joyce Corrington, based on the 1954 ...more

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Rabid is listed (or ranked) 23 on the list The Best Horror Movies About Virus Outbreaks
Rabid Marilyn Chambers, Joe Silver, Susan Roman Rabid is a 1977 Canadian drama horror film written and directed by David Cronenberg. It features Marilyn Chambers in the lead role, supported by Howard Ryshpan, Joe Silver and Robert A. ...more

24
18 11
Splinter is listed (or ranked) 24 on the list The Best Horror Movies About Virus Outbreaks
Splinter Jill Wagner, Paulo Costanzo, Shea Whigham Splinter is a 2008 horror film directed by Toby Wilkins. It had a limited theatrical release on October 31, 2008 and stars Shea Whigham, Paulo Costanzo, and Jill Wagner. It was filmed near ...more

25
14 8
Resident Evil: Degeneration is listed (or ranked) 25 on the list The Best Horror Movies About Virus Outbreaks
Resident Evil: Degeneration Laura Bailey, Johnny Yong Bosch, Kari Wahlgren Resident Evil: Degeneration, known in Japan as Biohazard: Degeneration, is the first full-length motion capture CG animation feature in Capcom's Resident Evil franchise. The film was made by ...more

26
15 9
Resident Evil: Damnation is listed (or ranked) 26 on the list The Best Horror Movies About Virus Outbreaks
Resident Evil: Damnation Dave Wittenberg, Robin Sachs, Michael McConnohie Resident Evil: Damnation, known as Biohazard: Damnation in Japan, is a 2012 Japanese feature-length computer-animated horror 3D film by Capcom and Sony Pictures Entertainment Japan, directed by ...more

27
18 12
Carriers is listed (or ranked) 27 on the list The Best Horror Movies About Virus Outbreaks
Carriers Emily VanCamp, Chris Pine, Piper Perabo Carriers is a 2009 American post-apocalyptic horror film written and directed by Àlex and David Pastor. It stars Lou Taylor Pucci, Chris Pine, Piper Perabo and Emily VanCamp as four ...more

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11 6
Shivers is listed (or ranked) 28 on the list The Best Horror Movies About Virus Outbreaks
Shivers Barbara Steele, Joe Silver, Vlasta Vrána Shivers is a 1975 Canadian science fiction body horror film written and directed by David Cronenberg.

29
15 10
Resident Evil: Afterlife is listed (or ranked) 29 on the list The Best Horror Movies About Virus Outbreaks
Resident Evil: Afterlife Milla Jovovich, Ali Larter, Wentworth Miller Resident Evil: Afterlife is a 2010 Canadian-German 3D science fiction action horror film written and directed by Paul W. S. Anderson. It stars Milla Jovovich, Ali Larter, Kim Coates, Shawn ...more

30
18 14
Viral is listed (or ranked) 30 on the list The Best Horror Movies About Virus Outbreaks

31
19 17
Contracted is listed (or ranked) 31 on the list The Best Horror Movies About Virus Outbreaks
Contracted Najarra Townsend, Caroline Williams, Katie Stegeman Contracted is a 2013 horror thriller film directed and written by Eric England. It was first released on November 23, 2013, in the United States and stars Najarra Townsend as a young woman that ...more

32
12 10
The Last Man on Earth is listed (or ranked) 32 on the list The Best Horror Movies About Virus Outbreaks
The Last Man on Earth Vincent Price, Giacomo Rossi-Stuart, Umberto Raho The Last Man on Earth is a 1964 science fiction horror film based on the Richard Matheson 1954 novel I Am Legend. The film was directed by Ubaldo Ragona and Sidney Salkow, and stars Vincent ...more

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Black Death is listed (or ranked) 33 on the list The Best Horror Movies About Virus Outbreaks
Black Death Sean Bean, Eddie Redmayne, Carice van Houten Black Death is a 2010 German-British action horror film directed by Christopher Smith from an original screenplay by Dario Poloni. It stars Sean Bean, Eddie Redmayne, and Carice van Houten. ...more

34
8 8
The Children is listed (or ranked) 34 on the list The Best Horror Movies About Virus Outbreaks
The Children Gale Garnett, Martin Shakar, Shannon Bolin The Children is a 1980 low budget horror film, written and produced by Carlton J. Albright. The movie is about five children in a small town who, thanks to a yellow toxic cloud, are transformed ...more

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7 7
Infection is listed (or ranked) 35 on the list The Best Horror Movies About Virus Outbreaks
Infection Yōko Maki, Kōichi Satō, Shirô Sano Infection is a 2004 Japanese horror film directed by Masayuki Ochiai, of a run-down hospital where a doctor's mistake unwittingly creates dark consequences for all. It was released as part of ...more

36
10 11
The Invasion is listed (or ranked) 36 on the list The Best Horror Movies About Virus Outbreaks
The Invasion Nicole Kidman, Daniel Craig, Malin Åkerman The Invasion is a 2007 science fiction thriller film starring Nicole Kidman and Daniel Craig, directed by Oliver Hirschbiegel, with additional scenes written by The Wachowskis and directed by ...more

37
9 10
Virus is listed (or ranked) 37 on the list The Best Horror Movies About Virus Outbreaks
Virus Jamie Lee Curtis, Donald Sutherland, William Baldwin Virus is a 1999 science fiction action thriller film directed by visual effects artist John Bruno. Starring Jamie Lee Curtis, William Baldwin and Donald Sutherland, the film is based on a Dark ...more

38
8 10
Mulberry Street is listed (or ranked) 38 on the list The Best Horror Movies About Virus Outbreaks
Mulberry Street John Hoyt, Debbie Rochon, Larry Fessenden Mulberry Street is a 2006 American horror film directed by Jim Mickle, written by Nick Damici and Jim Mickle, and starring Nick Damici. It was released by After Dark Films as a part of their 8 ...more

39
10 13
Antiviral is listed (or ranked) 39 on the list The Best Horror Movies About Virus Outbreaks
Antiviral Malcolm McDowell, Sarah Gadon, Nicholas Campbell Antiviral is a 2012 Canadian horror film directed by Brandon Cronenberg. The film competed in the Un Certain Regard section at the 2012 Cannes Film Festival. Cronenberg re-edited the film after ...more

40
18 24
The Happening is listed (or ranked) 40 on the list The Best Horror Movies About Virus Outbreaks
The Happening Zooey Deschanel, Mark Wahlberg, M. Night Shyamalan The Happening is a 2008 American supernatural thriller film written, co-produced, and directed by M. Night Shyamalan that follows a man, his wife, his best friend, and his friend's daughter as ...more

41
4 9
Virus is listed (or ranked) 41 on the list The Best Horror Movies About Virus Outbreaks
Virus George Kennedy, Robert Vaughn, Glenn Ford Virus — literally "Day of Resurrection" — is a 1980 post-apocalyptic science fiction movie directed by Kinji Fukasaku and based on a 1964 novel written by Sakyo Komatsu. It starred ...more

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5 11
Warning Sign is listed (or ranked) 42 on the list The Best Horror Movies About Virus Outbreaks
Warning Sign Sam Waterston, Yaphet Kotto, Kathleen Quinlan Warning Sign is a 1985 science fiction-horror film directed by Hal Barwood and starring Sam Waterston, Kathleen Quinlan, Yaphet Kotto, and Jeffrey DeMunn.

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4 10
Mutants is listed (or ranked) 43 on the list The Best Horror Movies About Virus Outbreaks
Mutants Michael Ironside, Steven Bauer, Louis Herthum Mutants is a 2008 horror film starring Michael Ironside.

44
3 10
I Drink Your Blood is listed (or ranked) 44 on the list The Best Horror Movies About Virus Outbreaks
I Drink Your Blood Bhaskar, Jadine Wong, Lynn Lowry I Drink Your Blood is a cult horror film originally released in 1970. The film was written and directed by David E. Durston, produced by Jerry Gross, and starred Bhaskar Roy Chowdhury and Lynn ...more

45
3 10
Last of the Living is listed (or ranked) 45 on the list The Best Horror Movies About Virus Outbreaks
Last of the Living Mark Hadlow, Robert Faith, Mark Hamilton Last of the Living is a 2009 New Zealand comedy-horror film written and directed by Logan McMillan.