Film The Best Movies About Disease Outbreaks  

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List Rules Films with epidemics of airborne illnesses or other infectious diseases that threaten humanity

A list of the Best Movies with disease outbreaks. Are you a fan of movies about scary infections and crazy medical pandemics? You might be surprised to find out how many movies were made with disease outbreaks in them. Browse through this list to see the best movies with disease outbreaks. Ranked in order of the most popular movie with disease outbreaks to the least popular, it will be easy to find a great movie to watch that was voted #1. If you see a good pandemic movie that you think should get a top spot, go ahead and vote for it to get it raised higher on the list.

If you don’t see your favorite disease outbreak movie listed here, go ahead and add it to the list so that others can enjoy it as much as you have. Movies like Contagion and Virus have a unique plot that leaves the viewer on the edge of their seat, but there are numerous good disease outbreak films to see, many of them just as suspenseful and fascinating as the last.

If you saw a favorite disease outbreak movie a long time ago but can’t remember the name, chances are you may find it on this list of the best disease outbreak movies. Then you can rent it or purchase it and enjoy the movie all over again! So go ahead and look through the list of best movies with disease outbreaks to find either a long-ago oldie or a brand new favorite to enjoy! One this is certain, the next time you get an infection, you'll probably start believing you've gotten caught up in a terrible new plague. But hey, at least you'll know how to fight it off!

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1
1,799 429
Contagion is listed (or ranked) 1 on the list The Best Movies About Disease Outbreaks
Gwyneth Paltrow, Kate Winslet, Matt Damon Contagion is a 2011 medical thriller directed by Steven Soderbergh. The film features an ensemble cast that includes Marion Cotillard, Bryan Cranston, Matt Damon, Laurence Fishburne, Jude Law, ...more

2
1,409 412
Outbreak is listed (or ranked) 2 on the list The Best Movies About Disease Outbreaks
WayneRaczek added Morgan Freeman, Kevin Spacey, Dustin Hoffman Outbreak is a 1995 American medical disaster film directed by Wolfgang Petersen and based on Richard Preston's non-fiction book The Hot Zone. The film stars Dustin Hoffman, Rene Russo, and ...more

3
1,452 313
28 Days Later is listed (or ranked) 3 on the list The Best Movies About Disease Outbreaks
Cillian Murphy, Christopher Eccleston, Naomie Harris 28 Days Later is a 2002 British post-apocalyptic horror film directed by Danny Boyle. The screenplay was written by Alex Garland. The film stars Cillian Murphy, Naomie Harris, Brendan Gleeson, ...more

4
1,327 437
World War Z is listed (or ranked) 4 on the list The Best Movies About Disease Outbreaks
jennifercorrea76 added Brad Pitt, Matthew Fox, David Morse World War Z is a 2013 American apocalyptic action horror film directed by Marc Forster. The screenplay by Matthew Michael Carnahan, Drew Goddard, and Damon Lindelof is from a screen story by ...more

5
910 271
28 Weeks Later is listed (or ranked) 5 on the list The Best Movies About Disease Outbreaks
Rose Byrne, Idris Elba, Jeremy Renner 28 Weeks Later is a 2007 British-Spanish post-apocalyptic science fiction horror film, structured as a sequel to the 2002 critical and commercial success, 28 Days Later. 28 Weeks Later was ...more

6
1,242 416
I Am Legend is listed (or ranked) 6 on the list The Best Movies About Disease Outbreaks
Will Smith, Emma Thompson, Salli Richardson I Am Legend is a 2007 American post-apocalyptic science fiction horror film directed by Francis Lawrence and starring Will Smith. It is the third feature film adaptation of Richard Matheson's ...more

7
679 240
12 Monkeys is listed (or ranked) 7 on the list The Best Movies About Disease Outbreaks
Brad Pitt, Bruce Willis, Christopher Plummer 12 Monkeys, also known as Twelve Monkeys, is a 1995 American science fiction film directed by Terry Gilliam, inspired by Chris Marker's 1962 short film La Jetée, and starring Bruce ...more

8
500 186
The Andromeda Strain is listed (or ranked) 8 on the list The Best Movies About Disease Outbreaks
Paula Kelly, David Wayne, Arthur Hill The Andromeda Strain is a 1971 American science fiction film produced and directed by Robert Wise. Based on Michael Crichton's 1969 novel of the same name and adapted by Nelson Gidding, the film ...more

9
614 188
The Crazies is listed (or ranked) 9 on the list The Best Movies About Disease Outbreaks
Danielle Panabaker, Timothy Olyphant, Radha Mitchell The Crazies is a 2010 American horror film directed by Breck Eisner, with a screenplay by Scott Kosar and Ray Wright. The film is a remake of the 1973 film of the same name by George A. Romero, ...more

10
642 262
Resident Evil is listed (or ranked) 10 on the list The Best Movies About Disease Outbreaks
Patrick Kelly0 added Milla Jovovich, Michelle Rodriguez, Jason Isaacs Resident Evil is a 2002 German-British-French science fiction horror film written and directed by Paul W. S. Anderson. The film stars Milla Jovovich and Michelle Rodriguez. It is the first ...more

11
429 151
The Stand is listed (or ranked) 11 on the list The Best Movies About Disease Outbreaks
Stephen King, Rob Lowe, Molly Ringwald The Stand is a 1994 American television miniseries based on the novel of the same name by Stephen King. King also wrote the teleplay, and has a cameo role in the series. It was directed by Mick ...more

12
528 209
Children of Men is listed (or ranked) 12 on the list The Best Movies About Disease Outbreaks
Julianne Moore, Clive Owen, Michael Caine Children of Men is a 2006 science fiction thriller film directed and co-written by Alfonso Cuarón. The screenplay, based on P. D. James's 1992 novel of the same name, was credited to five ...more

13
396 172
REC is listed (or ranked) 13 on the list The Best Movies About Disease Outbreaks
StacyWolfe added Manuela Velasco, Javier Botet, Ana Isabel Velásquez REC is a 2007 Spanish horror film, co-written and directed by Jaume Balagueró and Paco Plaza. The film was shot in Barcelona, Spain and the title is an abbreviation of the word ...more

14
221 49
Dawn of the Dead is listed (or ranked) 14 on the list The Best Movies About Disease Outbreaks
johnTthomas25 added Ving Rhames, Ty Burrell, Kevin Zegers Dawn of the Dead is a 2004 American horror film directed by Zack Snyder in his feature film directorial debut. A remake of George A. Romero's 1978 film of the same name, it is written by James ...more

15
419 233
Quarantine is listed (or ranked) 15 on the list The Best Movies About Disease Outbreaks
Dania Ramirez, Jennifer Carpenter, Doug Jones Quarantine is a 2008 American science fiction horror film directed by John Erick Dowdle and starring Jennifer Carpenter, Jay Hernandez, Columbus Short, Greg Germann, Steve Harris, Dania Ramirez, ...more

16
242 150
The Crazies is listed (or ranked) 16 on the list The Best Movies About Disease Outbreaks
StacyWolfe added Lynn Lowry, Harry Spillman, Richard Liberty The Crazies is a 1973 American science fiction horror-action film about the effects of the accidental release of a military biological weapon upon the inhabitants of a small American town. The ...more

17
273 146
Carriers is listed (or ranked) 17 on the list The Best Movies About Disease Outbreaks
Emily VanCamp, Chris Pine, Piper Perabo Carriers is a 2009 American post-apocalyptic horror film written and directed by Àlex and David Pastor. It stars Lou Taylor Pucci, Chris Pine, Piper Perabo and Emily VanCamp as four ...more

18
429 248
Rise of the Planet of the Apes is listed (or ranked) 18 on the list The Best Movies About Disease Outbreaks
James Franco, Freida Pinto, John Lithgow Rise of the Apes is in pre-production as of May 2010. This origin story for a new franchise takes place in modern day San Francisco and will star James Franco. It is currently scheduled for a ...more

19
200 135
The Omega Man is listed (or ranked) 19 on the list The Best Movies About Disease Outbreaks
Charlton Heston, Anthony Zerbe, Eric Laneuville The Omega Man is a 1971 American science fiction film directed by Boris Sagal and starring Charlton Heston. It was written by John William Corrington and Joyce Corrington, based on the 1954 ...more

20
288 195
Cabin Fever is listed (or ranked) 20 on the list The Best Movies About Disease Outbreaks
Eli Roth, Cerina Vincent, Jordan Ladd Cabin Fever is a 2002 American black comedy horror film directed by Eli Roth and starring Rider Strong, Jordan Ladd, James DeBello and Giuseppe Andrews. It was produced by Lauren Moews & ...more

21
123 44
Flu is listed (or ranked) 21 on the list The Best Movies About Disease Outbreaks
Soo Ae, Jang Hyuk, Cha In-pyo Flu is a 2013 South Korean disaster film written and directed by Kim Sung-su about an outbreak of a deadly disease which throws a city into chaos. It stars Jang Hyuk and Soo Ae.

22
204 154
REC 2 is listed (or ranked) 22 on the list The Best Movies About Disease Outbreaks
StacyWolfe added Manuela Velasco, Albert Grabuleda Capdevila, Javier Botet REC 2 is a 2009 Spanish horror film sequel to 2007's REC and the second installment of the REC series. The film was written and directed by Jaume Balagueró and Paco Plaza, both of whom ...more

23
208 121
Pandorum is listed (or ranked) 23 on the list The Best Movies About Disease Outbreaks
DickNixon added Dennis Quaid, Norman Reedus, Ben Foster Pandorum is a German-British 2009 post-apocalyptic science fiction film, with elements of locked room mystery, horror, and survival adventure. The film was directed by Christian Alvart and ...more

24
180 99
Serenity is listed (or ranked) 24 on the list The Best Movies About Disease Outbreaks
PatrickShanahan added Summer Glau, Morena Baccarin, Nathan Fillion Serenity is a 2005 American space western film written and directed by Joss Whedon. It is a continuation of Whedon's short-lived 2002 Fox science fiction television series Firefly and stars the ...more

25
133 75
The Bay is listed (or ranked) 25 on the list The Best Movies About Disease Outbreaks
DarrenTempleton added Will Rogers, Kristen Connolly, Andrew Stahl Chaos breaks out in a small Maryland town after an ecological disaster occurs.

26
315 243
The Happening is listed (or ranked) 26 on the list The Best Movies About Disease Outbreaks
Zooey Deschanel, Mark Wahlberg, M. Night Shyamalan The Happening is a 2008 American supernatural thriller film written, co-produced, and directed by M. Night Shyamalan that follows a man, his wife, his best friend, and his friend's daughter as ...more

27
190 148
Slither is listed (or ranked) 27 on the list The Best Movies About Disease Outbreaks
StacyWolfe added Elizabeth Banks, Jenna Fischer, Rob Zombie Slither is a 2006 American science fiction-comedy horror film written and directed by James Gunn in his directorial debut, and starring Nathan Fillion, Elizabeth Banks, Gregg Henry, and Michael ...more

28
88 36
The Maze Runner: Scorch Trials is listed (or ranked) 28 on the list The Best Movies About Disease Outbreaks
harmoniaclaire added Dylan O'Brien, Kaya Scodelario, Thomas Brodie-Sangster Maze Runner: The Scorch Trials is a 2015 American dystopian science fiction action thriller film directed by Wes Ball, based on the novel by James Dashner. Thomas (Dylan O'Brien) and his fellow ...more

29
190 108
Pontypool is listed (or ranked) 29 on the list The Best Movies About Disease Outbreaks
Stephen McHattie, Daniel Fathers, Boyd Banks Pontypool is a 2008 horror film directed by Bruce McDonald and adapted by Tony Burgess from Burgess' novel Pontypool Changes Everything.

30
104 57
Dreamcatcher is listed (or ranked) 30 on the list The Best Movies About Disease Outbreaks
looksharp added Morgan Freeman, Timothy Olyphant, Damian Lewis Dreamcatcher is a 2003 science fiction horror film adaptation of Stephen King's novel of the same name. It was directed by Lawrence Kasdan, and co-written by Kasdan and screenwriter William ...more

31
165 117
Blindness is listed (or ranked) 31 on the list The Best Movies About Disease Outbreaks
Julianne Moore, Mark Ruffalo, Sandra Oh Blindness is a 2008 Canadian film in English. It is an adaptation of the 1995 novel of the same name by Portuguese author José Saramago about a society suffering an epidemic of blindness. ...more

32
68 35
How I Live Now is listed (or ranked) 32 on the list The Best Movies About Disease Outbreaks
shannon-sullivan added Saoirse Ronan, Anna Chancellor, George MacKay How I Live Now is a 2013 British drama film based on the 2004 novel of the same name by Meg Rosoff, directed by Kevin Macdonald and script written by Tony Grisoni, Jeremy Brock and Penelope ...more

33
135 106
The Invasion is listed (or ranked) 33 on the list The Best Movies About Disease Outbreaks
rlynz30madeloso added Nicole Kidman, Daniel Craig, Malin Åkerman The Invasion is a 2007 science fiction thriller film starring Nicole Kidman and Daniel Craig, directed by Oliver Hirschbiegel, with additional scenes written by The Wachowskis and directed by ...more

34
201 156
Doomsday is listed (or ranked) 34 on the list The Best Movies About Disease Outbreaks
Rhona Mitra, Malcolm McDowell, Bob Hoskins Doomsday is a 2008 science fiction action film written and directed by Neil Marshall. The film takes place in the future in Scotland, which has been quarantined because of a deadly virus. When ...more

35
118 91
Splinter is listed (or ranked) 35 on the list The Best Movies About Disease Outbreaks
Jill Wagner, Paulo Costanzo, Shea Whigham Splinter is a 2008 horror film directed by Toby Wilkins. It had a limited theatrical release on October 31, 2008 and stars Shea Whigham, Paulo Costanzo, and Jill Wagner. It was filmed near ...more

36
87 79
The Thaw is listed (or ranked) 36 on the list The Best Movies About Disease Outbreaks
StacyWolfe added Val Kilmer, William B. Davis, Aaron Ashmore The Thaw is a 2009 science fiction horror/thriller film directed by Mark A. Lewis starring Val Kilmer and Martha MacIsaac.

37
61 14
10 Cloverfield Lane is listed (or ranked) 37 on the list The Best Movies About Disease Outbreaks
Patrick Kelly0 added John Goodman, Mary Elizabeth Winstead, John Gallagher 10 Cloverfield Lane is a 2016 American science fiction psychological thriller film directed by Dan Trachtenberg. The film was developed from a script titled The Cellar, but under production by ...more

38
67 44
Mimic is listed (or ranked) 38 on the list The Best Movies About Disease Outbreaks
looksharp added Josh Brolin, Mira Sorvino, Norman Reedus Mimic is an American 1997 science fiction horror film co-written and directed by Guillermo del Toro, based on a short story of the same name by Donald A. Wollheim. Del Toro was unhappy with the ...more

39
94 89
Virus is listed (or ranked) 39 on the list The Best Movies About Disease Outbreaks
George Kennedy, Robert Vaughn, Glenn Ford Virus — literally "Day of Resurrection" — is a 1980 post-apocalyptic science fiction movie directed by Kinji Fukasaku and based on a 1964 novel written by Sakyo Komatsu. It starred ...more

40
84 68
And the Band Played On is listed (or ranked) 40 on the list The Best Movies About Disease Outbreaks
Ian McKellen, Steve Martin, Richard Gere And the Band Played On is a 1993 American television film docudrama directed by Roger Spottiswoode. The teleplay by Arnold Schulman is based on the best-selling 1987 non-fiction book And the ...more

41
49 31
Land of the Dead is listed (or ranked) 41 on the list The Best Movies About Disease Outbreaks
johnTthomas25 added Dennis Hopper, Simon Pegg, Simon Baker Land of the Dead is a 2005 post-apocalyptic horror film written and directed by George A. Romero; the fourth of Romero's six Living Dead movies, it is preceded by Night of the Living Dead, Dawn ...more

42
47 13
The Girl With All The Gifts is listed (or ranked) 42 on the list The Best Movies About Disease Outbreaks
Patrick Kelly0 added Gemma Arterton, Paddy Considine, Glenn Close The Girl with All the Gifts is a 2016 British post-apocalyptic zombie horror drama film directed by Colm McCarthy and written by M.R. Carey adapted from his novel of the same name. The film ...more

43
34 22
Leviathan is listed (or ranked) 43 on the list The Best Movies About Disease Outbreaks
Peter Weller, Ernie Hudson, Daniel Stern Leviathan is a 1989 science fiction horror film about a hideous creature that stalks and kills a group of people in a sealed environment, in a similar vein to such films as Alien and The Thing. ...more

44
37 26
Dead Space: Downfall is listed (or ranked) 44 on the list The Best Movies About Disease Outbreaks
Kelly Hu, Kevin Michael Richardson, Grey DeLisle Dead Space: Downfall is an American animated horror film developed by Film Roman and EA. It is a prequel to the video game Dead Space and takes place during the events of Dead Space: Extraction, ...more

45
35 37
Pandemic is listed (or ranked) 45 on the list The Best Movies About Disease Outbreaks
Gabrielle Held added Tiffani Thiessen, Faye Dunaway, Eric Roberts Pandemic is a 2007 Hallmark Channel original mini-series with an ensemble cast. It premiered on Saturday, May 26, 2007 at 8:00 PM as part of Hallmark Channel's "Uncharted Adventures" ...more

46
99 115
REC 3: Génesis is listed (or ranked) 46 on the list The Best Movies About Disease Outbreaks
StacyWolfe added Leticia Dolera, Carla Nieto, Javier Botet REC 3: Génesis is a 2012 Spanish horror film directed by Paco Plaza. This film is the third installment of the REC series. It is a parallel sequel to the first two films, taking place ...more

47
41 32
The Last Man on Earth is listed (or ranked) 47 on the list The Best Movies About Disease Outbreaks
Vincent Price, Giacomo Rossi-Stuart, Umberto Raho The Last Man on Earth is a 1964 science fiction horror film based on the Richard Matheson 1954 novel I Am Legend. The film was directed by Ubaldo Ragona and Sidney Salkow, and stars Vincent ...more

48
59 71
The Masque of the Red Death is listed (or ranked) 48 on the list The Best Movies About Disease Outbreaks
Vincent Price, Jane Asher, Hazel Court The Masque of the Red Death is a 1964 British horror film directed by Roger Corman and starring Vincent Price. The story follows a prince who terrorizes a plague-ridden peasantry while ...more

49
35 28
Dead Space: Aftermath is listed (or ranked) 49 on the list The Best Movies About Disease Outbreaks
Christine Lakin, Graham McTavish, Christopher Judge Dead Space: Aftermath is an American animated horror film that bridges the storyline between Dead Space and Dead Space 2.

50
47 71
Rabid is listed (or ranked) 50 on the list The Best Movies About Disease Outbreaks
StacyWolfe added Marilyn Chambers, Joe Silver, Susan Roman Rabid is a 1977 Canadian drama horror film written and directed by David Cronenberg. It features Marilyn Chambers in the lead role, supported by Howard Ryshpan, Joe Silver and Robert A. ...more