Watchworthy

The Greatest TV Shows About Sisters 

Ranker TV
Updated May 22, 2020 949 votes 182 voters 8.8k views 41 items

List Rules Vote up your favorite shows featuring the sister-sister bond (or lack thereof), excluding any with sisters who aren't main stars, as well as brother-sister scenarios.

What do you think are the best shows about sisters? Many of us have one, but there aren't as many popular TV shows about sisters as you might imagine. For this list, the focus is entirely on series about or featuring two women who are sisters. Even if a character like Monica Geller (Friends) is a great example of a sister found on television, she isn't being considered because she doesn't have a sister of her own. TV shows about sisters may be hard to come by, but that doesn't mean there aren't some amazing sisters spread throughout television history—and this list compiles the best examples of them all.

Shows like The WB's (Now CW) Charmed integrates the characters' sisterhood as a core element of the show. Their magic works best when combined, making them some of the most powerful sisters in all of television. Other shows like Game of Thrones may not be the one you think of when trying to come up with an amazing TV show featuring sisters, but Arya and Sansa Stark are two of the most important characters in that series, which features dozens. Of course, we can't forget Tia and Tamera from the cast of Sister, Sister, not to mention the three lovely girls from Brady Bunch. In short, you can find plenty of good shows about sisters.

For more recommendations, browse this list of sister TV shows and feel free to add any similar shows and movies you think are missing! You might also be interested in checking out the best movies about sisters.

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list ordered by
1
Full House is listed (or ranked) 1 on the list The Greatest TV Shows About Sisters
Bob Saget, John Stamos, Dave Coulier

Premiered: 1987

Full House is an American sitcom created by Jeff Franklin for ABC. The show chronicles a widowed father, who enlists his best friend and his brother-in-law to help raise his three daughters. It ...more

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2
Sisters is listed (or ranked) 2 on the list The Greatest TV Shows About Sisters
Swoosie Kurtz, Patricia Kalember, Sela Ward

Premiered: 1991

Sisters is a television drama which aired on NBC for six seasons, from 1991 to 1996. The series was created by Ron Cowen and Daniel Lipman, who were also the executive producers and showrunners. ...more

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3
What I Like About You is listed (or ranked) 3 on the list The Greatest TV Shows About Sisters
Amanda Bynes, Jennie Garth, Wesley Jonathan

Premiered: 2002

What I Like About You is an American television sitcom set mainly in New York City, following the lives of two sisters, older-sister Valerie Tyler and teenager-sister Holly Tyler. The series ran ...more

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4
Charmed is listed (or ranked) 4 on the list The Greatest TV Shows About Sisters
Shannen Doherty, Holly Marie Combs, Alyssa Milano

Premiered: 1998

Charmed (The WB, 1998) is an American fantasy drama television series created by Constance M. Burge. Sisters Prue (Shannen Doherty), Piper (Holly Marie Combs) and Phoebe (Alyssa Milano) discover ...more

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5
Fuller House is listed (or ranked) 5 on the list The Greatest TV Shows About Sisters
Candace Cameron Bure, Jodie Sweeten, Andrea Barber

Premiered: 2016

Fuller House (Netflix, 2016) is an American family sitcom created by Jeff Franklin, and a sequel to the 1987–1995 television series. D.J. Tanner-Fuller (Candace Cameron Bure), now a widow and a ...more

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6
The Brady Bunch is listed (or ranked) 6 on the list The Greatest TV Shows About Sisters
Robert Reed, Florence Henderson, Ann B. Davis

Premiered: 1969

The Brady Bunch is an American sitcom created by Sherwood Schwartz that originally aired from September 26, 1969, to March 8, 1974, on ABC. The series revolves around a large blended family with ...more

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7
Sabrina, the Teenage Wit... is listed (or ranked) 7 on the list The Greatest TV Shows About Sisters
Dimos Dicoudis added Melissa Joan Hart, Caroline Rhea, Beth Broderick

Premiered: 1996

Sabrina, the Teenage Witch is an American sitcom based on the Archie comic book series of the same name. The show premiered on September 27, 1996, on ABC to over 17 million viewers in its ...more

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8
Wynonna Earp is listed (or ranked) 8 on the list The Greatest TV Shows About Sisters
Melanie Scrofano, Shamier Anderson, Tim Rozon

Premiered: 2016

Wynonna Earp (Syfy, 2016) is a Canadian-American supernatural Western horror television series created by Emily Andras, based on the comic book series by Beau Smith. With her unique abilities, ...more

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9
The Powerpuff Girls is listed (or ranked) 9 on the list The Greatest TV Shows About Sisters
Cathy Cavadini, Elizabeth Daily, Tara Strong

Premiered: 1998

The Powerpuff Girls is an American animated television series created by animator Craig McCracken and produced by Cartoon Network Studios for Cartoon Network. The show centers on Blossom, ...more

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10
Sister, Sister is listed (or ranked) 10 on the list The Greatest TV Shows About Sisters
Tia Mowry-Hardrict, Tamera Mowry-Housley, Jackée Harry

Premiered: 1994

Sister, Sister is an American television sitcom starring identical twins Tia and Tamera Mowry. It aired from 1994 to 1999. The premise of the show was that the girls were separated and adopted ...more

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11
Modern Family is listed (or ranked) 11 on the list The Greatest TV Shows About Sisters
Ed O'Neill, Sofía Vergara, Julie Bowen

Premiered: 2009

Modern Family (ABC, 2009) is an American comedy television sitcom created by Francisco Bobadilla. Three different but related families face trials and tribulations in their own unique way from ...more

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12
Orphan Black is listed (or ranked) 12 on the list The Greatest TV Shows About Sisters
Tatiana Maslany, Dylan Bruce, Jordan Gavaris

Premiered: 2013

Orphan Black is a Canadian science fiction television series created by screenwriter Graeme Manson and director John Fawcett, starring Tatiana Maslany as several identical people who are, in ...more

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13
Grey's Anatomy is listed (or ranked) 13 on the list The Greatest TV Shows About Sisters
Ellen Pompeo, Justin Chambers, Chandra Wilson

Premiered: 2005

Grey's Anatomy (ABC, 2005) is an American medical soap opera television series. The series focuses on the fictional lives of surgical interns and residents as they gradually evolve into seasoned ...more

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14
Game of Thrones is listed (or ranked) 14 on the list The Greatest TV Shows About Sisters
Peter Dinklage, Lena Headey, Emilia Clarke

Premiered: 2011

Game of Thrones (HBO, 2011) is an American fantasy drama television series created by David Benioff and D. B. Weiss, based on the series of fantasy novels by George R. R. Martin. Nine noble ...more

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15
Pretty Little Liars is listed (or ranked) 15 on the list The Greatest TV Shows About Sisters
Troian Bellisario, Ashley Benson, Lucy Hale

Premiered: 2010

Pretty Little Liars (ABC Family, 2010) is an American teen drama mystery–thriller television series developed by I. Marlene King, loosely based on the novel series by Sara Shepard. When their ...more

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16
The Fresh Prince of Bel-... is listed (or ranked) 16 on the list The Greatest TV Shows About Sisters
Will Smith, James Avery, Alfonso Ribeiro

Premiered: 1990

The Fresh Prince of Bel-Air is an American television sitcom that originally aired on NBC from September 10, 1990, to May 20, 1996. The show stars Will Smith as a fictionalized version of ...more

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17
Sweet Valley High is listed (or ranked) 17 on the list The Greatest TV Shows About Sisters
Brittany Daniel, Cynthia Daniel, Jason David Frank

Premiered: 1994

Sweet Valley High is an American Live-action comedy-drama series very loosely based on Francine Pascal's book series of the same name. The series ran from September 5, 1994 to October 14, 1997, ...more
18
Winx Club is listed (or ranked) 18 on the list The Greatest TV Shows About Sisters
Dimos Dicoudis added Liza Jacqueline, Caren Manuel, Helena Evangeliou

Premiered: 2004

Winx Club (2004) is an Italian animated television series directed, created and produced by Iginio Straffi and his company Rainbow S.r.l. in co-production with Rai Fiction. It is part of the ...more
19
Brothers and Sisters is listed (or ranked) 19 on the list The Greatest TV Shows About Sisters
Mary Crosby, William Windom, Larry Anderson

Premiered: 1979

Brothers and Sisters is an American sitcom that aired on NBC from January to April 1979. The series attempted to capitalize on the success of the 1978 motion picture National Lampoon's Animal ...more

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20
When Hope Calls is listed (or ranked) 20 on the list The Greatest TV Shows About Sisters
Morgan Kohan, Jocelyn Hudon, RJ Hatanaka

Premiered: 2019

When Hope Calls (Hallmark Movies Now, 2019) is an American drama television series created by Alfonso H. Moreno, and a spinoff of When Calls the Heart. Orphaned sisters Lillian (Morgan Kohan) ...more

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21
Family Ties is listed (or ranked) 21 on the list The Greatest TV Shows About Sisters
Michael J. Fox, Michael Gross, Meredith Baxter

Premiered: 1982

Family Ties is an American sitcom that aired on NBC from September 22, 1982 until May 14, 1989. The series, created by Gary David Goldberg, reflected the move in the United States from the ...more

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22
Beautiful People is listed (or ranked) 22 on the list The Greatest TV Shows About Sisters
Jackson Rathbone, Torrey DeVitto, Daphne Zuniga

Premiered: 2005

Beautiful People is an American drama television series about a family that moves from New Mexico to The Big Apple to make a fresh start on their lives. The series aired on the ABC Family ...more
23
Three Sisters is listed (or ranked) 23 on the list The Greatest TV Shows About Sisters
Dyan Cannon, A. J. Langer, Vicki Lewis

Premiered: 2001

Three Sisters is an American television sitcom that aired on NBC for two seasons from January 9, 2001, to February 5, 2002.
24
Jem is listed (or ranked) 24 on the list The Greatest TV Shows About Sisters
Dimos Dicoudis added Samantha Newark, Patricia Alice Albrecht, Cathianne Blore

Premiered: 1985

Jem, also known as Jem and the Holograms, is an American animated television series that ran from 1985 to 1988 in U.S. first-run syndication. The series is about music company owner Jerrica ...more

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25
Sabrina: The Animated Se... is listed (or ranked) 25 on the list The Greatest TV Shows About Sisters
Dimos Dicoudis added Emily Hart, Melissa Joan Hart, Nick Bakay

Premiered: 1999

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