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The Best X-Men Villains and Enemies Ever

Updated April 5, 2021 64.8k votes 5.1k voters 98.5k views139 items

List RulesVote up all your favorite X-Men adversaries and villains!

The X-Men are a team of mutants whose purpose is to see that humans and mutants coexist peacefully in the pages of Marvel Comics. Unfortunately, not everyone sees eye to eye with the X-Men. There are as many X-Men bad guys as Jay Leno has cars. Meaning a lot. Some which have popped up in the popular X-Men movies.

Many human organizations like the Friends of Humanity think that mutants should be eliminated or banned from living normal lives as their powers are too much of a threat. X-Villains like Apocalypse, Magneto, and Mister Sinister have also been wreaking havoc on the X-Men since 1963, Magneto being their first X-Men villain they’ve faced. Even some of the X-Men themselves have crossed the line to the dark side or even started out naughty, like Rogue, who was a member of the Brotherhood of Evil Mutants. Wolverine and the X-Men can't even catch a break in their popular blockbuster films against the likes of the Hellfire Club, Lady Deathstrike, and the X-Men enemy Sabretooth.

We have for you this list of X-Men villains that make up the X-Men rogues gallery. But which are the greatest X-Men baddies to go up against our favorite mutants? Is Magneto, the Master of Magnetism your favorite X-Men bad guy, or can you not resist the shapeshifting Mystique?

Make sure to vote up all your favorite X-Men evildoers and vote down the ones you think aren't worth the X-Men's valuable time. This X-Men villains list does not include all X-Men enemies. You have the option to add in the X-Men foes we missed, so make sure add your favorite X Men villains.