Companies Founded in St. Louis

List of notable businesses founded in St. Louis, listed alphabetically with corporate logos when available. This list includes some of the largest, most profitable companies that were founded in St. Louis. The famous St. Louis companies and corporations on this list include both public and private corporations. You can find information about the popular companies on this list, such as what industry they're part of. When available you can click on the successful St. Louis company's names to find out even more about them.

This list is made up of a variety of items, including Panera Bread and Monsanto.

This list answers the questions, "What companies were founded in St. Louis?" and "What are the biggest St. Louis companies?"

If you're a St. Louis native then this list of the biggest St. Louis companies will make you proud. This list is also an excellent resource if you're doing research on reputable businesses from St. Louis.

  • Anheuser-Busch
    Malt Beverages, Brewing
    Anheuser-Busch Companies, Inc. is an American brewing company and a wholly owned subsidiary of Anheuser-Busch InBev. The company operates 12 breweries in the United States. Until December 2009, it ...more
  • Baldor Electric Company
    Manufacturing, Motors and Generators
    Baldor Electric Company markets, designs, and manufactures industrial electric motors, mechanical power transmission products, drives, and generator sets. The company manufactures its products in 20 ...more
  • Dyke


    Established in St.Louis in 1899 by A.L.Dyke, Dyke was the first American auto parts business. Dyke also sold early autos, kit car or assembled. In addition to the Dyke name, the company also sold ...more
  • Eagle Industries
    Broadwoven Fabric Mills, Broadwoven Fabric Mills, Manmade Fiber and Silk
    Eagle Industries makes tactical gear for the military and law enforcement.  The company was purchased by Alliant Techsystems Inc. (NYSE: ATK) on March 31, 2009.
  • Express Scripts
    Health Care, Pharmacies and Drug Stores
    Express Scripts Holding Company is a Fortune 100 company as of 2013, the 20th-largest in the United States and is the largest pharmacy benefit management organization in the United States, with 2013 ...more
  • HOK


    Architectural Services, Engineering
    HOK is a global design, architecture, engineering and urban planning firm. As of 2015, HOK is the largest U.S.-based architecture-engineering firm and the second-largest interior design firm. The ...more