Famous Co-Stars Who Became Besties In Real Life  

Mariel Loveland
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List Rules Vote up your favorite famous bestie duos.

Life sometimes imitates art, and that's definitely the case with these co-stars who are friends in real life. There are some beautiful platonic friendships portrayed in film, and it's even better when those fictional pals are actual pals. From Jennifer Aniston and Courteney Cox, who formed a lifelong sisterhood after starring as Rachel and Monica in Friends, one of the best duos of all time, to Jimmy Fallon and Justin Timberlake, who met on SNL, these famous best friends make us wish we were part of their squad.

Jennifer Aniston And Courteney Cox
Jennifer Aniston And Courteney... is listed (or ranked) 1 on the list Famous Co-Stars Who Became Besties In Real Life
Photo: Friends/NBC

How They Met: Jennifer Aniston and Courteney Cox were an instantly recognizable duo from the moment they stepped foot in Central Perk. The pair played best friends and roommates Rachel Green and Monica Geller on the critically acclaimed hit Friends. Their on-screen chemistry made the show legendary. 

Friendship Goals: The pair have managed to stay close throughout the decades. Cox has no problem going to bat for Aniston. When Aniston was being dragged through the mud during ex-hubby Brad Pitt's divorce from Angelina Jolie, Cox was there to slam the negative press. In turn, Aniston sometimes babysits for Cox and lets her daughter, Coco, play dress up in her multi-million dollar wardrobe. That's real love!

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Donald Faison And Zach Braff

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How They Met: J.D. and Turk's friendship was many fans' favorite part of Scrubs. It turns out that Donald Faison and Zach Braff were just doing what felt natural. The pair became lifelong besties after playing doctors on the long-running series.

Friendship Goals: Faison and Braff are your typical best bros. They exchange silly banter on Twitter, play tennis together, and even have bizarre best friend phone cases. They are so close that Braff claimed they practically invented the concept of bromance.

“It has to be real. The only way to have a real bromance is if you’re genuinely fond of each other. [Faison's] my best friend. I’m really fond of that man, I’m not ashamed to say it. And to the supporters of our bromance, I’d like to say, thank you," Braff said.

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Seth Rogen And James Franco

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How They Met: In 1999, the young actors starred in the short-lived series Freaks & Geeks.

Friendship Goals: James Franco and Seth Rogen have stayed close since they were part of the same group of slackers who hung out in the bleachers at William McKinley High School. The pair have become a comedy powerhouse with major credits like Pineapple Express and This Is The End under their belt—and they're not afraid to get a little weird. Franco once painted scandalous nude portraits of his best bro and posted them on Instagram.

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Justin Timberlake And Jimmy Fallon

How They Met: Justin Timberlake and Jimmy Fallon's heartwarming bromance started at the 2002 MTV VMA Awards and blossomed on the set of Saturday Night Live. The pair met at nerve-wracking moments in their respective careers. Fallon was a first-time award show host, and Timberlake was newly performing solo after leaving *NSYNC. Since then, they've been thick as thieves. 

Friendship Goals: Aside from slaying their SNL appearances, the bros have been known to enjoy tandem bike rides. Timberlake and Fallon regularly perform sketches on Fallon's talk show, including the reoccuring "Camp Winnipesaukee." In 2011, the best bros won the co-title of GQ's Showmen of the Year.

"We’re good luck to each other—like each other’s rabbit foots," Fallon told the magazine.

Things finally came full circle in 2013 when Fallon presented Timberlake with the Michael Jackson Video Vanguard Award at the VMAs. His speech was so touching, it made bros everyone text their BFFs, "Sup, U Good?"

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