A List of Famous Lead Guitarists with photos! These are musicians who are masters of their craft. While it is often the singers who claim all the fame, these musicians are famous in their own right. As time has past and music evolved, the list of musical instruments available has grown, especially with the advent of the digital age. While the vocalist may have his lyrics, it is the musicians behind him, who truly make the sound. After all, instrumentals are as popular as ever, but acappellas are few and far between. Best of all, with our modern recording technology, we will be able to enjoy these artists for centuries if not millennia!