Femme fatales aren't exclusive to old Noir films - although they do appear in the anime Noir. These characters are wildly attractive women who use their sex appeal to manipulate their enemies.
Some femme fatale anime characters, like the legendary Fujiko Mine of Lupin III, are simply looking to steal from their targets, but others like Rize Kamishiro of Tokyo Ghoul, have more sinister and violent goals. They're sexy and therefore fun to look at, but the best thing about these characters is how complicated they often are. Many of them have complex reasons for turning toward less than savory acts, and their backstories are just as compelling as their looks, if not more so.
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This homunculus inspires lust in just about everyone she encounters, and she uses those feelings to her advantage, luring men in and then violently disposing of them.
Kurumi has personally destroyed at least 10,000 people, so she's definitely got the "fatale" part covered. With her adorably sexy appearance and her increasing levels of emotional depth, she ends up fitting the whole femme fatale package.