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Diseases / Medical Conditions

These are the diseases that would be deal breakers for me, life-wise.

Horrible Diseases I Would Rather Die Than Have

Best Medical Conditions Lists, Top 10 Diseases- Find any Disease List at Ranker

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Science

Best Rankings of Interesting Scientific Facts, Topics, and Cool Science News

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Erectile dysfunction

Erectile dysfunction or impotence is sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity. A penile erection is the hydraulic effect of blood entering and being retained in sponge-like bodies within the penis. The process is most often initiated as a result of sexual arousal, when signals are transmitted from the brain to nerves in the penis. The most important organic causes are cardiovascular disease and diabetes, neurological problems, hormonal insufficiencies and drug side effects.
Psychological impotence is where erection or penetration fails due to thoughts or feelings rather than physical impossibility; this is somewhat less frequent but can often be helped. Notably in psychological impotence, there is a strong response to placebo treatment. Erectile dysfunction can have severe psychological consequences as it can be tied to relationship difficulties and masculine self-image generally.
Besides treating the underlying causes such as potassium deficiency or arsenic contamination of drinking water, the first line treatment of erectile dysfunction consists of a trial of PDE5 inhibitor drugs.

Dissociative identity disorder

Dissociative Identity Disorder, previously known as Multiple Personality Disorder, is a mental disorder on the dissociative spectrum characterized by at least two distinct and relatively enduring identities or dissociated personality states that alternately control a person's behavior, and is accompanied by memory impairment for important information not explained by ordinary forgetfulness. These symptoms are not accounted for by substance abuse, seizures, other medical conditions, nor by imaginative play in children. Diagnosis is often difficult as there is considerable comorbidity with other mental disorders. Malingering should be considered if there is possible financial or forensic gain, as well as factitious disorder if help-seeking behavior is prominent.
DID is one of the most controversial psychiatric disorders with no clear consensus regarding its diagnosis or treatment. Research on effectiveness of treatment has been concerned primarily with clinical approaches and case studies. Dissociative symptoms range from common lapses in attention, becoming distracted by something else, and daydreaming, to pathological dissociative disorders.

The human immunodeficiency virus is a lentivirus that causes the acquired immunodeficiency syndrome, a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells.
HIV infects vital cells in the human immune system such as helper T cells, macrophages, and dendritic cells. HIV infection leads to low levels of CD4⁺ T cells through a number of mechanisms, including apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4⁺ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4⁺ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections.

Ebola virus disease

Ebola virus disease, or simply Ebola, is a disease of humans and other primates caused by ebolaviruses. Signs and symptoms typically start between two days and three weeks after contracting the virus with a fever, sore throat, muscular pain, and headaches. Then, vomiting, diarrhea and rash usually follow, along with decreased function of the liver and kidneys. At this time some people begin to bleed both internally and externally. The disease has a high risk of death, killing between 25 and 90 percent of those infected with an average of about 50 percent. This is often due to low blood pressure from fluid loss, and typically follows six to sixteen days after symptoms appear.
The virus spreads by direct contact with body fluids, such as blood, of an infected human or other animals. This may also occur through contact with an item recently contaminated with bodily fluids. Spread of the disease through the air between primates, including humans, has not been documented in either laboratory or natural conditions. Semen or breast milk of a person after recovery from EVD may still carry the virus for several weeks to months.

Necrotizing fasciitis

Necrotizing fasciitis or NF, commonly known as flesh-eating disease, flesh-eating bacteria or flesh-eating bacteria syndrome, is a rare infection of the deeper layers of skin and subcutaneous tissues, easily spreading across the fascial plane within the subcutaneous tissue. The most consistent feature of necrotizing fasciitis was first described in 1952 as necrosis of the subcutaneous tissue and fascia with relative sparing of the underlying muscle.
Necrotizing fasciitis progresses rapidly, having greater risk of developing in the immunocompromised due to conditions such as diabetes or cancer. It is a severe disease of sudden onset and is usually treated immediately with surgical debridement and large doses of intravenous antibiotics, with delay in surgical treatment being associated with higher mortality.
Many types of bacteria can cause necrotizing fasciitis. The disease is classified as Type I or Type II. The majority of cases of necrotizing fasciitis are polymicrobial, with 25–45% of cases being Type II. Such infections are more likely to occur in people with compromised immune systems secondary to chronic disease.

Alzheimer's disease

Alzheimer's Disease is a progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.

Progeria

Progeria is an extremely rare genetic disorder wherein symptoms resembling aspects of aging are manifested at a very early age. Progeria is one of several progeroid syndromes. The word progeria comes from the Greek words "pro", meaning "before" or "premature", and "gēras", meaning "old age". The disorder has a very low incidence rate, occurring in an estimated 1 per 8 million live births. Those born with progeria typically live to their mid teens to early twenties. It is a genetic condition that occurs as a new mutation, and is rarely inherited, as carriers usually do not live to reproduce. Although the term progeria applies strictly speaking to all diseases characterized by premature aging symptoms, and is often used as such, it is often applied specifically in reference to Hutchinson–Gilford progeria syndrome.
Scientists are particularly interested in progeria because it might reveal clues about the normal process of aging. Progeria was first described in 1886 by Jonathan Hutchinson. It was also described independently in 1897 by Hastings Gilford. The condition was later named Hutchinson–Gilford progeria syndrome.

Lupus erythematosus

Lupus erythematosus is a name given to a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks normal, healthy tissues. Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs.

Histoid leprosy

Histoid leprosy is a skin condition, a rare form of multibacillary leprosy.

Genital herpes

Herpes genitalis is a genital infection caused by the herpes simplex virus. A 1998 study indicated it was the most common sexually transmitted infection by the number of cases. Most individuals carrying herpes are unaware they have been infected and many will never suffer an outbreak, which involves blisters similar to cold sores. While there is no cure for herpes, over time symptoms are increasingly mild and outbreaks are decreasingly frequent.
HSV has been classified into two distinct categories, HSV-1 and HSV-2. Although genital herpes was previously caused primarily by HSV-2, genital HSV-1 infections are increasing and now cause up to 80% of infections.
When symptomatic, the typical manifestation of a primary HSV-1 or HSV-2 genital infection is clusters of genital sores consisting of inflamed papules and vesicles on the outer surface of the genitals, resembling cold sores. These usually appear 4–7 days after sexual exposure to HSV for the first time. Genital HSV-1 infection recurs at rate of about one sixth of that of genital HSV-2.


 
 
 #1 Erectile dysfunction, #2 Dissociative identity disorder, #3 HIV, #4 Ebola virus disease, #5 Necrotizing fasciitis
 
