18 Times Anime Characters Went Through Horrible Human Experimentation

No list on human experimentation would be complete without the tragic story of Nina Tucker. Not only was she the subject of a brutal experiment, but the person responsible for her suffering was also the man who should have been most invested in protecting her: her father.

In order to keep his job as a state alchemist, Shou Tucker produced a "chimera" that could speak. While that earned him some acclaim, he still needed another chimera - and he got one. How did he accomplish this difficult task? By fusing his daughter with the family dog, creating a being that could not enjoy life as either a little girl or a dog. This wasn't the first time he'd done such a terrible thing - the first chimera was a fusion of his wife and another dog.

While Tucker doesn't have as many victims as some of the other evil scientists discussed on this list, the fact that the victims were so close to him makes him one of the most reprehensible anime villains of all time. 

Many people assume that Koro-sensei is an alien, but that's far from the truth. Actually, he's a human being whose body is partially composed of anti-matter due to a series of painful experiments. Originally an assassin, he was betrayed by his apprentice and imprisoned in a laboratory. The experiments he endured there gave him some amazing powers, like near-invulnerability and the ability to travel at Mach 20, but they also made his body so unstable that if no one stopped him, he would explode and destroy planet Earth.

That's actually what led him to work with Class 3-E. He claims that the impending destruction is intentional, but offers humanity the opportunity to stop him on one condition - that he be allowed to teach a group of middle schoolers that Aguri, a woman he met in the lab, was forced to leave behind. 

The Abyss is a gaping hole in the ground that's incredibly difficult to study because everyone who ventures down there is hit with the Curse of the Abyss when it's time for the ascent. Once you get to the bottom of the Abyss, the curse can cause severe symptoms like agonizing pain, loss of humanity, and death. Scientists are always looking for ways to counter this, and a man named Bowndred decides to trick a group of orphans into a fatal experiment. 

The only survivors of the experiment are Mitty and Nanachi. The two of them are sent down to the sixth layer of the Abyss in an elevator designed to push the curse onto only one person, allowing the other to survive. Mitty takes the brunt of the curse and transforms into an inhuman being with few cognitive abilities. Nanachi's body transformed as well, but it wasn't as dramatic. After that, Nanachi is forced to work for Bowndred while he repeatedly destroys Mitty's body to see how many times she can reform herself - since the curse has made her more or less immortal. Nanachi eventually runs away with Mitty on their back. 

For a young girl, Eri has gone through a lifetime of suffering. Her Quirk, Rewind, is incredibly powerful since she has the ability to rewind a living person's body back to its original state. She can even rewind someone to a point before they existed. Unfortunately, this happened to her father when she was just a baby as she doesn't know how to control her Quirk. Overhaul discovers her powers and uses it for the Yakuza's benefit by experimenting on her to develop Quirk-Destroying drugs and bullets. He continuously breaks down her body, and when she's on the verge of death, he brings her back to life with his Quirk.

When Crona was a small child, their mother Medusa replaced all of their blood with a substance called Black Blood. The Black Blood was combined with a melted down magical weapon called Ragnorak. While this gave Crona a wide and impressive range of supernatural abilities, it was also a painful process for the newborn to endure. Also, Medusa wanted to use Crona's abilities for her own nefarious purposes, often forcing the child to take lives and punishing them with isolation and abuse if they refused. 

Lucy is a Diclonius, which means that she's a humanlike being with a few key differences: namely, her horns and her psychokinetic abilities. Due to both her status as a Diclonius and her tendency toward violent rampages, Lucy is held captive in a laboratory for three excruciating years. There, she endures painful experiments at the hands of unscrupulous scientists. Already inclined toward destroying humans, she eventually escapes by tearing the place apart and taking the lives of every scientist or guard who tries to get in her way.