Supernatural would never have been the hit series it was had it not been for the chemistry between the lead pair. Jensen Ackles and Jared Padalecki are best friends in real life, but the fandom considers them to be much closer. And honestly, the way they act together in public, they could easily be mistaken for real-life brothers.
Here are times where the actors that played Sam and Dean on Supernatural proved they were basically brothers in real life as well.
1. Jensen Might Be Older But No Gray Hairs Here
2. The Uncle Title Is Official
3. You Get No Respect When J2M Are Around
4. Classic Little Brother Annoying The Older Brother
5. Someone's In Trouble
6. To Be Fair, They Really Are Too Similar