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'Osmosis Jones' Is A Fever Dream Of A Movie

Updated 27 Sep 2019 248.6k views13 items

Osmosis Jones is one of the weirdest animated movies ever made. It tells the story of a white blood cell (voiced by Chris Rock) trying to save his human host from a deadly virus (Laurence Fishburne). In live-action scenes that are interspersed throughout, Bill Murray plays Frank, the human in question. He gets sicker and sicker as the movie goes on, thanks to the contaminated food he unwisely eats while working at a zoo. 

Osmosis Jones is unique and imaginative in the way it portrays the human body. Frank's insides are depicted as a great big city with its own government, transportation system, and communities of cells, germs, and bacteria. Over the course of the story, our titular hero travels to virtually every part of Frank, from the brain to the bladder, from a mucous membrane to a zit. Puns abound as Osmosis Jones references an impressive number of parts of the human body. 

Movies taking place inside a human body are nothing new. Fantastic Voyage and Innerspace did it first. Osmosis Jones does it differently, though, using animation to elevate the concept to its extreme. It's a trippy film, especially considering that it's aimed at children. If you've never seen this wacko masterpiece, or have forgotten just how bonkers it is, here's a recap of all the highlights.

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