If you're looking for extremely powerful vampires in anime, then you've come to the right place. Vicious bloodsuckers come in all forms, even anime form. Some of them wield weapons, some of them use magic, and most of them are immortal, but all of these vampires seriously slay when it comes to a challenge. This list is full of the most fearsome and brutal blood fiends in anime, so vote up the vampire characters that are truly vicious, and vote down the ones that don't really do much justice for the vampire race.
These powerful psychic, telekinetic, supernatural beings dominate in anime. After being blessed (or cursed) with vampirism, their strength grows along with their everlasting age, sometimes to the point where their abilities make them a bit too powerful. If vampires are supposed to be immortal, these anime vampires surely prove that they can withstand the tests of time... and the occasional vampire hunter.
Alucard is Hellsing Ultimate's main protagonist and the Hellsing Organization's most powerful weapon. He is basically untouchable and immortal. He has all sorts of incredible abilities that make him totally overpowered, like his ability to regenerate himself after any damage is done, shapeshifting powers, and the ability to walk through solid objects.
Seras Victoria is new to being a vampire, but she's still super tough. She has extraordinary abilities with wielding weapons, especially her rifle. Her superhuman strength and clairvoyant abilities coupled with gun-slinging action make her a truly vicious vampire.
Just because D is only half-vampire doesn't mean he isn't tough. His immortality, superhuman strength, and excellent marksmanship with basically every known weapon make this character from Vampire Hunter D a force to be reckoned with. His connection to the Sacred Ancestor has given him superior vampire abilities, even when compared to pureblood vampires.
This katana-wielding vampire is one of the oldest and most powerful vampires on the planet; she just doesn't know it right away. While recovering from amnesia, Saya Otonashi from Blood+ gradually regains her memories and her ability to use her amazing ancient vampire powers along with them.