Film Fictional Movie Drugs That Would Give You The Most Intense Highs  

Eric Conner
259 votes 81 voters 6.7k views 17 items

List Rules Vote up the hardcore movie drugs you'd least want to be on at a family reunion.

Trainspotting had heroin, Walter White his crystal meth (Blue Ice: accept no substitutes!). Alex in A Clockwork Orange partook of his moloko plus with a side of ultra-violence. Haven't heard of that one? Don't worry - you're not out of touch with the young folk. You just need to see more movies with hardcore fictional drugs. And make no mistake: there are some insane drugs in movies. Stuff that will make you lose your mind. Some drug movies will probably even make you feel like you're on drugs yourself. 

The beauty of a fictional narcotic is that writers and directors need not worry about the pesky truth that comes with dabbling in reality. And let's face it - Batman would be a lot less fun if the Joker used crack instead of Smylex. Speaking of crack, some of the films on this list, such as Robocop 2, are obvious examples of how the crack epidemic influenced movies. Leave a comment below if you feel any of the craziest drugs from movies didn't make this list. 

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Maybe you didn't see Gaspar Noe's three-hour drug trip Enter the Void because you've done DMT enough to not need to see it recreated as cinema. In the event you did see that movie, you know it's trippy as hell. So imagine that super trippiness in a movie that's a bit like Die Hard and a lot like The Raid and you have some idea of what's going on with Slo Mo in Dredd. The drug slows the user's perception of reality to 1% normal speed. And so you become high af and everything is magical. Sounds kind of great, right? 

Actors: Lena Headey, Karl Urban, Olivia Thirlby, Domhnall Gleeson, Deobia Oparei, + more

Initial Release: 2012

Directed by: Pete Travis

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#42 on The Best Science Fiction Action Movies

#66 on The Best Superhero Movies Ever Made

#42 on The Greatest Comic Book Movies of All Time

#49 on The Greatest Movie Remakes of All Time

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A Scanner Darkly isn't just about drugs; watching it, you feel the effects of drugs coming alive in front of your eyes. Using rotoscope-style animation, director Richard Linklater puts the audience right into the fractured brain of undercover agent Bob Arctor (Keanu Reeves). Arctor eventually becomes addicted to the drug he's trying to get off the streets - Substance D, a powerful psychedelic. The deeper in he gets, the more addicted he becomes, and the stranger the film gets.  

Actors: Robert Downey Jr., Keanu Reeves, Winona Ryder, Woody Harrelson, Alex Jones, + more

Initial Release: 2006

Directed by: Richard Linklater

Also Ranked

#85 on The Best Dystopian and Near Future Movies

#30 on The Best Movies About Split Personalities

#14 on The Greatest Animated Sci Fi Movies

#17 on The Best Movies About Surveillance and Hidden Cameras

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A Clockwork Orange is listed (or ranked) 3 on the list Fictional Movie Drugs That Would Give You The Most Intense Highs
Photo:  Warner Bros

A slightly more unhinged version of taro milk tea (with boba, obviously), moloko plus, from the Korova milkbar, is the drink and drug of choice for anti-hero Alex and his violent misfit cronies in A Clockwork Orange

To quote Alex, "The Korova milkbar sold milk-plus, milk plus vellocet or synthemesc or drencrom, which is what we were drinking. This would sharpen you up and make you ready for a bit of the old ultraviolence." Side effects may include a propensity to act out whenever Singing in the Rain enters your head, wanton raping, and a desire to turn every social encounter into an act of sadistic violence.   

As ad campaigns go, it's no "Got Milk." But if ultraviolence is your thing, then Korova's the drink for you. Accept no substitutes.  

Actors: Malcolm McDowell, Warren Clarke, Steven Berkoff, David Prowse, Adrienne Corri, + more

Initial Release: 1971

Directed by: Stanley Kubrick

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#30 on The Best Movies Based on Books

#2 on The Best Movies You Never Want to Watch Again

#4 on The Most Nausea-Inducing Great Films

#4 on The Best Dystopian and Near Future Movies

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Pineapple Express is listed (or ranked) 4 on the list Fictional Movie Drugs That Would Give You The Most Intense Highs
Photo:  Columbia Pictures

Pineapple Express, a formerly fictional, now very real, strain of marijuana, gave Pineapple Express it's name. And it is serious weed. It's not, "let's smoke and listen to Sabbath and joy ride in the '77 Monte Carlo" weed. it's "let's smoke this and awaken our third eye" weed. And it gets Dale Denton (Seth Rogen) and Saul Silver (James Franco) into all kinds of predicaments (though gets them out of a few, too). Weed might not seem like the most hardcore of drugs, but when it gets you into shoot outs with gangsters, it's safe to say this sh*t is for real. 

Actors: Amber Heard, James Franco, Seth Rogen, Bill Hader, Rosie Perez, + more

Initial Release: 2008

Directed by: David Gordon Green

Also Ranked

#53 on The Best Movies to Watch on Mushrooms

#1 on The Best Movies to Watch While Stoned

#7 on The Best Judd Apatow Movies

#1 on The Funniest Comedy Movies About Weed

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