Weird The Worst Prescription Drug Side Effects  

Jacob Shelton
527.1k views 20 items

Everything has a side effect, from coffee to Tylenol to eating too much pizza (that’s called “getting rad”). Most prescription drug side effects are usually not that big of deal. Who cares about having dry mouth when you don’t have blood clots, right? Unfortunately, the more costly and specific the medication, the worse the side effect usually is.

While most people start taking medication with the understanding that what they’re taking is going to make them healthy, they rarely realize that they might have their brain, gait, and even skin color altered irreversibly. Once you get about halfway through this collection of strange medicine side effects, you’ll start to notice that a lot of medications that alter the way you think (anti-smoking medication, anti-depressants) can really mess you up, unless you’re into having lucid nightmares. 

It’s a pipe dream to believe that there can medication without side effects, but it’s hard to believe that anyone would willingly subject their body to something knowing that there’s a small chance that they could kill their family. We’re not trying to be alarmist, we’re just trying to help. As Francis Bacon said, “Knowledge is power.”

Here are the worst and weirdest side effect to prescription medication. And if you’ve experienced any of the effects on this list (or effects that were even weirder) tell us about your experience in the comments.


Olanzapine is listed (or ranked) 1 on the list The Worst Prescription Drug Side Effects
Photo: vimeo

If you're someone who loves the way you walk, then you should find another way to treat your schizophrenia and bipolar disorder. Not only does Olanzapine come with the possibility of giving you an "abnormal gait," but it also comes with "cogwheel-like rigidity," and a "mask-like face." 


Mirapex is listed (or ranked) 2 on the list The Worst Prescription Drug Side Effects
Photo: Boris Thaser/Flickr
For those of you with someone in your life who's dealing with Parkinson's disease or Restless Leg Syndrome, you may be familiar with Mirapex. Hopefully, they aren't also fighting off unusual urges to gamble while they try to sit still. 


Ortho-Novum is listed (or ranked) 3 on the list The Worst Prescription Drug Side Effects
Photo:  Anqa/Pixabay/CC0 1.0
Ortho-Novum is one of the most popular birth controls on the market. And while it is a contraceptive, a lot of women use it to treat severe acne. Great! What's not so great is that it can cause benign but dangerous liver tumors that can rupture and cause fatal internal bleeding. 


Advair is listed (or ranked) 4 on the list The Worst Prescription Drug Side Effects
Photo: Jonathan Harford/flickr/CC-BY-NC 2.0
If you or someone you know has very intense asthma, then you've probably seen one of Advair's purple inhalers. In a sick twist, one of the first side effects listed on Advair's website is asthma related death. You just can't win when you've got a set of bum lungs.