Anime Underground

The 25 Best Sibling Duos In Anime History 

Jonah Dorrance
Updated June 14, 2019 25.1k votes 5.2k voters 42.1k views 25 items

List Rules Vote up the characters whose family brings you the most joy.

For anime fans looking for double or even six times the fun and adventure in a new series, the answer is here: sibling protagonist anime. Siblings of the standard hero and heroine are lucky to have more than a name, but these series feature entire families as main characters. A few series on the list promote pairs of siblings that are part of a larger cast of characters, as seen in Gintama or Ouran High School Host Club, so while they may not be the ultimate protagonist of their shows, they influence the story, are given ample screen time, and undergo their own development.

The stories of these brothers and sisters span multiple genres, from slice of life to science fiction. The companionship and close-knit relationships between these siblings range from beautifully loyal to questionably affectionate, but their journey together is no less entertaining. Which sibling anime is the favorite? Vote up your favorite duos and dynamics!

list ordered by
1
Full Metal Alchemist: Br... is listed (or ranked) 1 on the list The 25 Best Sibling Duos In Anime History
Full Metal Alchemist: Brotherhood
2
Blue Exorcist is listed (or ranked) 2 on the list The 25 Best Sibling Duos In Anime History
Blue Exorcist

Rin and Yukio Okumura

3
Ouran Highschool Host Cl... is listed (or ranked) 3 on the list The 25 Best Sibling Duos In Anime History
Ouran Highschool Host Club

Hikaru and Kaoru Hitachiin

4
No Game No Life is listed (or ranked) 4 on the list The 25 Best Sibling Duos In Anime History
No Game No Life

Sora and Shiro.

5
Attack on Titan is listed (or ranked) 5 on the list The 25 Best Sibling Duos In Anime History
6
Ranker Video
Seraph of the End

Yūichirō and Mikaela Hyakuya

7
Kill la Kill is listed (or ranked) 7 on the list The 25 Best Sibling Duos In Anime History
8
My Neighbor Totoro is listed (or ranked) 8 on the list The 25 Best Sibling Duos In Anime History
9
The Irregular at Magic H... is listed (or ranked) 9 on the list The 25 Best Sibling Duos In Anime History
The Irregular at Magic High School

Tatsuya and Miyuki Shiba

10
Tengan Toppa Gurren Lagg... is listed (or ranked) 10 on the list The 25 Best Sibling Duos In Anime History
Tengan Toppa Gurren Laggan

Kamina and Simon

11
Mob Psycho 100 is listed (or ranked) 11 on the list The 25 Best Sibling Duos In Anime History
Mob Psycho 100

Shigeo and Ritsu Kageyama.

12
Beyond the Boundary is listed (or ranked) 12 on the list The 25 Best Sibling Duos In Anime History
Beyond the Boundary

Hiroomi and Mitsuki Nase

13
Himouto! Umaru-chan is listed (or ranked) 13 on the list The 25 Best Sibling Duos In Anime History
Himouto! Umaru-chan

Taihei and Umaru Doma

14
Terror In Resonance is listed (or ranked) 14 on the list The 25 Best Sibling Duos In Anime History
Terror In Resonance

Arata Kokonoe "Nine" and Toji Hisama "Twelve".

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15
Gintama is listed (or ranked) 15 on the list The 25 Best Sibling Duos In Anime History
Gintama

Otae and Shinpachi Shimura

16
Monogatari Series is listed (or ranked) 16 on the list The 25 Best Sibling Duos In Anime History
Monogatari Series

Koyomi, Karen, and Tsukihi Araragi

17
Castle Town Dandelion is listed (or ranked) 17 on the list The 25 Best Sibling Duos In Anime History
Castle Town Dandelion

The Sakurada Siblings

18
Ultimate Otaku Teacher ... is listed (or ranked) 18 on the list The 25 Best Sibling Duos In Anime History
Ultimate Otaku Teacher

Junichiro and Suzune Kagami

19
Osomatsu-San is listed (or ranked) 19 on the list The 25 Best Sibling Duos In Anime History
Osomatsu-San

The Matsuno Sextuplets.

20
You and Me is listed (or ranked) 20 on the list The 25 Best Sibling Duos In Anime History
You and Me

Yuta and Yuki Asaba

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21
Monster is listed (or ranked) 21 on the list The 25 Best Sibling Duos In Anime History
22
Oreimo is listed (or ranked) 22 on the list The 25 Best Sibling Duos In Anime History
23
Space Brothers is listed (or ranked) 23 on the list The 25 Best Sibling Duos In Anime History
Space Brothers

Mutta and Hibito Nanba.

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24
Danchigai is listed (or ranked) 24 on the list The 25 Best Sibling Duos In Anime History
Danchigai

The Nakano siblings

25
Girlish Number is listed (or ranked) 25 on the list The 25 Best Sibling Duos In Anime History
Girlish Number

Gojo and Chitose Karasuma

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