Anime Underground The 25 Best Sibling Duos In Anime History  

Jonah Dorrance
17.3k votes 3.4k voters 25.1k views 25 items

List Rules Vote up the characters whose family brings you the most joy.

For anime fans looking for double or even six times the fun and adventure in a new series, the answer is here: sibling protagonist anime. Siblings of the standard hero and heroine are lucky to have more than a name, but these series feature entire families as main characters. A few series on the list promote pairs of siblings that are part of a larger cast of characters, as seen in Gintama or Ouran High School Host Club, so while they may not be the ultimate protagonist of their shows, they influence the story, are given ample screen time, and undergo their own development.

The stories of these brothers and sisters span multiple genres, from slice of life to science fiction. The companionship and close-knit relationships between these siblings range from beautifully loyal to questionably affectionate, but their journey together is no less entertaining. Which sibling anime is the favorite? Vote up your favorite duos and dynamics!

list ordered by

1
1,967 209
Full Metal Alchemist: Brotherh... is listed (or ranked) 1 on the list The 25 Best Sibling Duos In Anime History
Full Metal Alchemist: Brotherhood

Edward and Alphonse Elric.

2
1,675 207
Blue Exorcist is listed (or ranked) 2 on the list The 25 Best Sibling Duos In Anime History
Blue Exorcist

Rin and Yukio Okumura

3
1,196 350
Ouran Highschool Host Club is listed (or ranked) 3 on the list The 25 Best Sibling Duos In Anime History
Ouran Highschool Host Club

Hikaru and Kaoru Hitachiin

4
926 254
No Game No Life is listed (or ranked) 4 on the list The 25 Best Sibling Duos In Anime History
No Game No Life

Sora and Shiro.

5
1,068 447
Attack on Titan is listed (or ranked) 5 on the list The 25 Best Sibling Duos In Anime History

Eren Yeager and Mikasa Ackerman.

6
639 274
Kill la Kill is listed (or ranked) 6 on the list The 25 Best Sibling Duos In Anime History

Satsuki and Ryoko Kiryuin.

7
590 247
Ranker Video
Seraph of the End

Yūichirō and Mikaela Hyakuya

8
535 224
My Neighbor Totoro is listed (or ranked) 8 on the list The 25 Best Sibling Duos In Anime History
My Neighbor Totoro

Satsuki and Mei Kusakabe

9
569 247
Tengan Toppa Gurren Laggan is listed (or ranked) 9 on the list The 25 Best Sibling Duos In Anime History
Tengan Toppa Gurren Laggan

Kamina and Simon

10
585 263
The Irregular at Magic High Sc... is listed (or ranked) 10 on the list The 25 Best Sibling Duos In Anime History
The Irregular at Magic High School

Tatsuya and Miyuki Shiba

11
263 197
Mob Psycho 100 is listed (or ranked) 11 on the list The 25 Best Sibling Duos In Anime History
Mob Psycho 100

Shigeo and Ritsu Kageyama.

12
216 231
Himouto! Umaru-chan is listed (or ranked) 12 on the list The 25 Best Sibling Duos In Anime History
Himouto! Umaru-chan

Taihei and Umaru Doma

13
202 213
Beyond the Boundary is listed (or ranked) 13 on the list The 25 Best Sibling Duos In Anime History
Beyond the Boundary

Hiroomi and Mitsuki Nase

14
201 215
Terror In Resonance is listed (or ranked) 14 on the list The 25 Best Sibling Duos In Anime History
Terror In Resonance

Arata Kokonoe "Nine" and Toji Hisama "Twelve".

15
164 225
Gintama is listed (or ranked) 15 on the list The 25 Best Sibling Duos In Anime History
Gintama

Otae and Shinpachi Shimura

16
117 207
Monogatari Series is listed (or ranked) 16 on the list The 25 Best Sibling Duos In Anime History
Monogatari Series

Koyomi, Karen, and Tsukihi Araragi

17
103 210
Ultimate Otaku Teacher is listed (or ranked) 17 on the list The 25 Best Sibling Duos In Anime History
Ultimate Otaku Teacher

Junichiro and Suzune Kagami

18
89 191
Castle Town Dandelion is listed (or ranked) 18 on the list The 25 Best Sibling Duos In Anime History
Castle Town Dandelion

The Sakurada Siblings

19
97 215
Osomatsu-San is listed (or ranked) 19 on the list The 25 Best Sibling Duos In Anime History
Osomatsu-San

The Matsuno Sextuplets.

20
120 287
Oreimo is listed (or ranked) 20 on the list The 25 Best Sibling Duos In Anime History

Kyosuke and Kirino Kosaka

21
61 199
Monster is listed (or ranked) 21 on the list The 25 Best Sibling Duos In Anime History

Johan and Nina Liebert

22
51 181
You and Me is listed (or ranked) 22 on the list The 25 Best Sibling Duos In Anime History
You and Me

Yuta and Yuki Asaba

23
48 179
Space Brothers is listed (or ranked) 23 on the list The 25 Best Sibling Duos In Anime History

Mutta and Hibito Nanba.

24
42 177
Danchigai is listed (or ranked) 24 on the list The 25 Best Sibling Duos In Anime History
Danchigai

The Nakano siblings

25
41 177
Girlish Number is listed (or ranked) 25 on the list The 25 Best Sibling Duos In Anime History
Girlish Number

Gojo and Chitose Karasuma