Anime Underground The 25 Best Sibling Duos In Anime History  

Jonah Dorrance
17.3k votes 3.4k voters 25k views 25 items

List Rules Vote up the characters whose family brings you the most joy.

For anime fans looking for double or even six times the fun and adventure in a new series, the answer is here: sibling protagonist anime. Siblings of the standard hero and heroine are lucky to have more than a name, but these series feature entire families as main characters. A few series on the list promote pairs of siblings that are part of a larger cast of characters, as seen in Gintama or Ouran High School Host Club, so while they may not be the ultimate protagonist of their shows, they influence the story, are given ample screen time, and undergo their own development.

The stories of these brothers and sisters span multiple genres, from slice of life to science fiction. The companionship and close-knit relationships between these siblings range from beautifully loyal to questionably affectionate, but their journey together is no less entertaining. Which sibling anime is the favorite? Vote up your favorite duos and dynamics!

list ordered by

1
1,964 209
Full Metal Alchemist: Brotherh... is listed (or ranked) 1 on the list The 25 Best Sibling Duos In Anime History
Full Metal Alchemist: Brotherhood

Edward and Alphonse Elric.

2
1,673 206
Blue Exorcist is listed (or ranked) 2 on the list The 25 Best Sibling Duos In Anime History
Blue Exorcist

Rin and Yukio Okumura

3
1,195 349
Ouran Highschool Host Club is listed (or ranked) 3 on the list The 25 Best Sibling Duos In Anime History
Ouran Highschool Host Club

Hikaru and Kaoru Hitachiin

4
924 253
No Game No Life is listed (or ranked) 4 on the list The 25 Best Sibling Duos In Anime History
No Game No Life

Sora and Shiro.

5
1,066 445
Attack on Titan is listed (or ranked) 5 on the list The 25 Best Sibling Duos In Anime History

Eren Yeager and Mikasa Ackerman.

6
638 273
Kill la Kill is listed (or ranked) 6 on the list The 25 Best Sibling Duos In Anime History

Satsuki and Ryoko Kiryuin.

7
589 246
Ranker Video
Seraph of the End

Yūichirō and Mikaela Hyakuya

8
535 223
My Neighbor Totoro is listed (or ranked) 8 on the list The 25 Best Sibling Duos In Anime History
My Neighbor Totoro

Satsuki and Mei Kusakabe

9
569 246
Tengan Toppa Gurren Laggan is listed (or ranked) 9 on the list The 25 Best Sibling Duos In Anime History
Tengan Toppa Gurren Laggan

Kamina and Simon

10
585 261
The Irregular at Magic High Sc... is listed (or ranked) 10 on the list The 25 Best Sibling Duos In Anime History
The Irregular at Magic High School

Tatsuya and Miyuki Shiba

11
262 197
Mob Psycho 100 is listed (or ranked) 11 on the list The 25 Best Sibling Duos In Anime History
Mob Psycho 100

Shigeo and Ritsu Kageyama.

12
202 212
Beyond the Boundary is listed (or ranked) 12 on the list The 25 Best Sibling Duos In Anime History
Beyond the Boundary

Hiroomi and Mitsuki Nase

13
215 231
Himouto! Umaru-chan is listed (or ranked) 13 on the list The 25 Best Sibling Duos In Anime History
Himouto! Umaru-chan

Taihei and Umaru Doma

14
201 213
Terror In Resonance is listed (or ranked) 14 on the list The 25 Best Sibling Duos In Anime History
Terror In Resonance

Arata Kokonoe "Nine" and Toji Hisama "Twelve".

15
164 224
Gintama is listed (or ranked) 15 on the list The 25 Best Sibling Duos In Anime History
Gintama

Otae and Shinpachi Shimura

16
116 206
Monogatari Series is listed (or ranked) 16 on the list The 25 Best Sibling Duos In Anime History
Monogatari Series

Koyomi, Karen, and Tsukihi Araragi

17
103 209
Ultimate Otaku Teacher is listed (or ranked) 17 on the list The 25 Best Sibling Duos In Anime History
Ultimate Otaku Teacher

Junichiro and Suzune Kagami

18
89 190
Castle Town Dandelion is listed (or ranked) 18 on the list The 25 Best Sibling Duos In Anime History
Castle Town Dandelion

The Sakurada Siblings

19
96 215
Osomatsu-San is listed (or ranked) 19 on the list The 25 Best Sibling Duos In Anime History
Osomatsu-San

The Matsuno Sextuplets.

20
120 286
Oreimo is listed (or ranked) 20 on the list The 25 Best Sibling Duos In Anime History

Kyosuke and Kirino Kosaka

21
61 198
Monster is listed (or ranked) 21 on the list The 25 Best Sibling Duos In Anime History

Johan and Nina Liebert

22
51 180
You and Me is listed (or ranked) 22 on the list The 25 Best Sibling Duos In Anime History
You and Me

Yuta and Yuki Asaba

23
48 178
Space Brothers is listed (or ranked) 23 on the list The 25 Best Sibling Duos In Anime History

Mutta and Hibito Nanba.

24
42 177
Danchigai is listed (or ranked) 24 on the list The 25 Best Sibling Duos In Anime History
Danchigai

The Nakano siblings

25
41 176
Girlish Number is listed (or ranked) 25 on the list The 25 Best Sibling Duos In Anime History
Girlish Number

Gojo and Chitose Karasuma