Most comic fans would agree Lex Luthor is the smartest supervillain in DC and Doctor Doom is the smartest supervillain in Marvel. But is that actually the case? They're certainly the most famous smart bad guys in their respective universes - but are either of them actually the smartest supervillain of all time? There are a lot of deep cuts out there that give both of these comic book heavyweights a run for their money.
If Reed Richards is the smartest superhero (which he is), then it stands to reason that the Maker (an evil Reed Richards) is among the smartest supervillains - if not the actual smartest. Or what about Otto Octavius, a villain so smart he actually defeated his arch-nemesis and took over for Spider-Man? If Lex Luthor is so smart, why can't he ever seem to best Superman? It's about time it was declared once and for all who the smartest supervillain really is.