List of diseases that include splenomegaly as a symptom. Any major, well-known medical conditions associated with splenomegaly are included below, listed alphabetically with photos when available. Any maladies, sicknesses or illnesses with splenomegaly as a symptom can be seen below. For any real, further diagnosis of something you feel you might have, please consult a doctor. This list includes information about each disease, such as what risks are associated with it. The list you're viewing has a variety of illnesses, like Hepatitis and Cirrhosis, in it.This list answers the questions, "What risks are associated with splenomegaly?" and "What disease can I have if I have splenomegaly?"