The human body is capable of many things, including miraculous feats of strength and a surprising ability to bounce back from damage. We also know our bodies are complicated systems that can malfunction and turn on us, creating rare medical conditions which sound like legends told around a campfire. One of these is Fibrodysplasia ossificans progressiva, a condition in which people whose muscles turn to bone slowly lose all mobility and eventually die.
Can people really turn to stone? Technically no, but people's bodies can turn on them and calcify parts of their bodies - such as the muscles and tendons - and cause a tremendous amount of pain. Continue reading for stone man syndrome facts and learn how this rare but deadly disease takes hold.
It Turns Soft Tissue Into Bone Throughout The Body, Essentially Turning The Sufferer Into Stone
Humans are born with soft bones, cartilage, and growth plates that facilitate the creation of bone in their bodies. Cartilage forms at the end of growth plates, and then ossification takes over to create permanent bones. This continues throughout our teen years but comes to a stop once we reach adulthood.
This is not the case with Fibrodysplasia ossificans progressiva (FOP). A person's bones will continue to grow by overtaking their soft tissue and calcifying it. As the ossification continues to claim the muscles, ligaments, and tendons, it starts to hinder the movement of the sufferer.
Eventually the bones will fuse together, making it nearly impossible for the sufferer to move without assistance. The disease becomes very expensive at this point, as a caretaker may be needed to facilitate the everyday care of the patient. Wheelchairs and walkers may also be needed to aid the patient in retaining some amount of freedom.
The Disorder Can Cause Malnutrition And Difficulty Breathing, Which Can Lead To Death
When doctors say FOP takes over muscles and connective tissue, they are also referring to those that exist in the jaws. This leads to a hardening of the muscles in the face, which creates a reduced ability to open and close one's mouth. When this happens, it is very easy for someone with FOP to suffer from malnutrition.
Another part of the body impacted by the disease is the area around the ribcage. Since the ribcage uses the cartilage connections within itself to expand and contract with the lungs, FOP can negatively impact a patient's ability to breathe. In fact, studies show most deaths that occur in people with FOP are caused by cardio-respiratory failure caused by this restriction.
Muscle Trauma Can Lead To An Increase In Ossification
People bump themselves on furniture or fall all of the time, and they get a bruise or a broken bone as a result. Even if the break is severe, it will eventually heal. This isn't the case of people who suffer from this calcifying condition. People with FOP who fall down or bump their leg are likely to intensify the ossification of their body at the point of impact.
Children and adults who have FOP have to stop playing sports to avoid advancing the rate of their disease progression. At some point, most sufferers become bedridden and have to rely on the help of others to get by, but avoiding dangerous situations where injury is likely can push that eventuality further into their future.
Another culprit which triggers flare-ups of ossification is a simple virus. If someone with FOP gets the flu or other viral illness, it can kickstart their disease.
Surgery Would Only Make The Disease Worse For The Sufferer
In the past, doctors have attempted to remove the calcified tissue from the body of people with FOP. They soon realized the traumatic nature of surgery was a catalyst triggering the growth of new bone. Surgery is not an option for FOP sufferers.
Unfortunately, many people have to have surgery in the course of their lives. Any time someone with FOP does require surgery, it is almost guaranteed the procedure will prompt a calcifying reaction.