Health The Worst Drugs for You  

Brettski
Originally by
61.1k votes 7.6k voters 291.5k views 50 items

List Rules Vote up any substance that affects the body, regardless of legality.

There is no question that certain drugs have specific benefits when used correctly, but where do we draw the line between drugs that are helpful and drugs that are harmful? Adderall, a stimulant, is extremely beneficial when it comes to helping someone focus when it is either difficult or unachievable, but when addiction sets in and daily function can no longer persist without the aid of that drug, has the helpful/harmful line been irrevocably crossed? Are we now in the territory of the most dangerous drugs or even the worst drugs in the world?

This list seeks to engage readers in a thoughtful discourse about what the worst drugs for you really are, and not which ones are simply the most addictive drugs (though many of the worst ones will likely also be the most addictive). The important thing to remember when considering what the most harmful drugs are is that there is no solid line between bad drugs and good drugs; many will consider alcohol an innocuous substance while others would rank it above crystal meth based on personal experiences.

Most times, when people begin using any type of drug, they do it seeking some sort of benefit such as stress relief from marijuana, increased focus from Ritalin, or pain relief from morphine. When the search for pleasure becomes a quest to relieve the pain of addiction or a fractured life brought on by a drug, that is when it crosses into the harmful category.

This list, as you may have gathered with the introduction of alcohol into the conversation, is not just about the most harmful illegal drugs, it's a catch-all of prescription drugs, pharmaceuticals, and "harmless" substances like caffeine. This poll is here to gather the opinions of real people as opposed to doctors and lawmakers who would deem the majority of this list of drugs harmful if used in any situation. All of the drugs on this list of worst drugs has a positive use and a negative abuse, and the point is to sort out one from the other and determine what the worst drugs really are (based on intended use, actual use, and potential addiction and side effects).

If you think a drug has no potential benefit for its user and will only come with negative side effects, vote it up to the top of the list of most harmful drugs. If you think something has a continuing value to the user and society, vote it down and make it known you think it is a harmless drug (or at least a beneficial drug when used correctly). If you think there is a drug that's bad for you not listed, make sure to add it so it can be part of the debate on which drug is the worst for you.

list ordered by
1
2,305 542
Desomorphine is listed (or ranked) 1 on the list The Worst Drugs for You
rvrijn1980 added
Desomorphine is a derivative of morphine with powerful, fast-acting opioid effects, such as sedation and analgesia. First synthesized in 1932 and patented in 1934, desomorphine was used in ...more
2
2,220 539
Heroin is listed (or ranked) 2 on the list The Worst Drugs for You
Heroin and commonly known by its street names of H, smack, boy, horse, brown, black, tar, and others is an opioid analgesic originally synthesized by C.R. Alder Wright in 1874 by adding two ...more
3
2,153 522
Methamphetamine is listed (or ranked) 3 on the list The Worst Drugs for You
Methamphetamine is a potent central nervous system stimulant of the phenethylamine and amphetamine classes that is used as a recreational drug and, rarely, to treat attention deficit ...more
4
1,692 400
Crack cocaine is listed (or ranked) 4 on the list The Worst Drugs for You
Crack cocaine is the freebase form of cocaine that can be smoked. It may also be termed rock, work, hard, iron, cavvy, base, or just crack; the Manual of Adolescent Substance Abuse Treatment ...more
5
1,235 234
Mephedrone is listed (or ranked) 5 on the list The Worst Drugs for You
modestas-kaminskas added Bath Salts
Mephedrone, also known as 4-methylmethcathinone or 4-methylephedrone, is a synthetic stimulant drug of the amphetamine and cathinone classes. Slang names include drone, MCAT, and Meow Meow. It ...more
6
1,344 372
Phencyclidine is listed (or ranked) 6 on the list The Worst Drugs for You
PCP
Phencyclidine, commonly initialized as PCP and known colloquially as angel dust, KJ, illy, or wet, is a recreational dissociative drug. Formerly used as an anesthetic agent, PCP exhibits ...more
7
310 34
Fentanyl is listed (or ranked) 7 on the list The Worst Drugs for You
MattLennon(matt.justmatt.) added
A synthetic, lipophilic phenylpiperidine opioid agonist with analgesic and anesthetic properties. Fentanyl selectively binds to the mu-receptor in the central nervous system (CNS) thereby ...more
8
1,202 455
Inhalants is listed (or ranked) 8 on the list The Worst Drugs for You
9
1,079 433
K2 (AKA Spice) is listed (or ranked) 9 on the list The Worst Drugs for You
K2 (AKA Spice)
10
1,165 541
Speed is listed (or ranked) 10 on the list The Worst Drugs for You
11
1,048 564
Oxycodone is listed (or ranked) 11 on the list The Worst Drugs for You
Oxycodone is a semisynthetic opioid synthesized from thebaine, an opioid alkaloid found in the Persian poppy and one of the many opioid alkaloids found in the opium poppy. It is an analgesic ...more
12
913 526
Morphine is listed (or ranked) 12 on the list The Worst Drugs for You
An opiate alkaloid isolated from the plant Papaver somniferum and produced synthetically. Morphine binds to and activates specific opiate receptors (delta, mu and kappa), each of which are ...more
13
1,116 674
Cocaine is listed (or ranked) 13 on the list The Worst Drugs for You
Cocaine is a tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" and the alkaloid suffix "-ine", forming "cocaine". It ...more
14
1,424 766
Alcohol is listed (or ranked) 14 on the list The Worst Drugs for You
Alcohol
15
714 351
Rohypnol is listed (or ranked) 15 on the list The Worst Drugs for You
16
765 440
Methadone is listed (or ranked) 16 on the list The Worst Drugs for You
A synthetic opioid with analgesic activity. Methadone mimics the actions of endogenous peptides at CNS opioid receptors, primarily on the mu-receptor and has actions similar to those of morphine ...more
17
493 304
Ketamine is listed (or ranked) 17 on the list The Worst Drugs for You
modestas-kaminskas added
A cyclohexanone derivative with analgesic and anesthetic properties. Although its mechanism of action is not well understood, ketamine appears exerts complex pharmacological actions including ...more
18
678 390
Barbituates is listed (or ranked) 18 on the list The Worst Drugs for You
19
652 443
Alprazolam is listed (or ranked) 19 on the list The Worst Drugs for You
JustinKim added
A triazolobenzodiazepine agent with anxiolytic, sedative-hypnotic and anticonvulsant activities. Alprazolam binds to a specific site distinct from the inhibitory neurotransmitter ...more
20
755 485
Opium is listed (or ranked) 20 on the list The Worst Drugs for You
Opium is the dried latex obtained from the opium poppy. Opium latex contains approximately 12% of the analgesic alkaloid morphine, which is processed chemically to produce heroin and other ...more
21
685 459
Anabolic Steroids is listed (or ranked) 21 on the list The Worst Drugs for You
22
532 375
Methaqualone is listed (or ranked) 22 on the list The Worst Drugs for You
Quaaludes
Methaqualone is a sedative-hypnotic drug that is similar in effect to barbiturates, a general central nervous system depressant. The sedative–hypnotic activity of methaqualone was first noted by ...more
23
525 385
Tranquilizers is listed (or ranked) 23 on the list The Worst Drugs for You
24
668 522
Tobacco leaf extract is listed (or ranked) 24 on the list The Worst Drugs for You
25
470 367
Methylphenidate is listed (or ranked) 25 on the list The Worst Drugs for You
Methylphenidate is a central nervous system stimulant of the phenethylamine and piperidine classes that is used in the treatment of attention deficit hyperactivity disorder, postural orthostatic ...more