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The Greatest Video Game Sisters (But You're Glad They Aren't Your Sister)

Although it's not a common occurance, there are a handful cool video game characters that are sisters. Sometimes the best backup in times of strife is a little help from your family, and these sisters definitely have each others back. There are lots of amazing female characters in video games, but some of the greatest are also related to each other. Some of them could even give Mario and Luigi a run for their money. In groups or in pairs, rivals or accomplices, these sisters are some of the toughest, weirdest, greatest, and most enduring video game characters of all time. From the little sisters of Bioshock to the Great Giana Sisters, we've included every pair of sisters we could think of in video game history. Vote below on your favorite sisters in video games. Are we missing a few that you really love? Let us know in the comments, and we might just add them to the list!
  • 1
    125 VOTES

    Mileena and Kitana

    Hailing from the Outer Realm, Mileena and Kitana are both ninja warriors in the the Mortal Kombat series. Mileena fights with scythes, and Kitana fights with a steel fan. 
    Great characters?
  • 2
    112 VOTES

    Anna and Nina Williams

    Anna and Nina Williams are both skilled assassins in the Tekken series. They have a volatile, competitive relationship, and are often depicted as rivals.
    Great characters?
  • 3
    116 VOTES

    Sophitia and Cassandra

    The daughters of a Greek baker, Sophitia and Cassandra are sexy supernatural warriors in the the Soulcalibur fighting series.
    Great characters?
  • 4
    87 VOTES

    Maya and Mia Fey

    Maya and MIa Fey appear together in Phoenix Wright: Ace Attourney episode "Turnabout Sisters," in which younger sister Maya is accused of murdering her older sister, longtime character Mia Fey.
    Great characters?