There doesn't exist a loser sorer than the villains who activate self-destruct as their plans start to unravel. It's a cowardly and pathetic move, equivalent to a child flipping a game board over when a losing villain decides he may as well terminate everyone around him since he can't achieve his goals. A good villain gives the hero one last word of wisdom to think about, typically about how their entire worldview is wrong before they gracefully dip out.
Who knows why villains are so mad when they lose anyway, it's almost always their own fault. Half the time a villain loses, it's because they literally outlined their entire plan. But, it's not like a villain becomes a villain because they have normal, regulated emotions - so no one can really act confused after these guys flip out and try to destroy the world they can't control.
- Photo: Paramount Pictures
Khan is a genetically engineered human who spent years in cryosleep but is later awoken by Starfleet. Admiral Marcus forces Khan to work for him by threatening to terminate Khan's crew, who are still trapped in cryosleep. While working for Marcus, Khan tries and fails to free his men.
In Star Trek Into Darkness, Khan's sole goal is to rescue his crew. But, while battling with the Enterprise, Khan's crew is slain. So, without any of his men, and with an infinite amount of anger directed at Starfleet, Khan crashes his massive ship known as the Vengeance into San Francisco in an attempt to eradicate Starfleet headquarters.
Captain America and company’s first mission in Civil War is stopping Crossbones from swiping a biological weapon. Naturally, thanks to the combined skills of multiple Avengers, Crossbones is stopped with relative ease.
However, he isn’t one to go down quietly, so he decides to blow himself up and tries to take Captain America down with him. This leads to Scarlet Witch throwing Crossbones away from Cap, but her actions inadvertently cause the demises of harmless civilians.
- Photo: 20th Century Fox
Throughout the first Predator, the Predator hunts humans in the name of what seems to be sport. The Predator slays people, sure, but he seems to abide by a set of rules. For instance, the Predator doesn't go after an unarmed opponent. And, at the end of the film, the Predator drops its own weapon to engage Dutch in hand-to-hand combat. But, the pleasantries melt way after Dutch defeats the Predator.
Faced with his own demise, the Predator tries to take Dutch with him by activating his self-destruct mechanism.
- Photo: New Line Cinema
After defeating Shredder's henchmen, Tokka and Rahzar, the turtles face off against Shredder alone. Four against one should be easy, but Shredder's no slouch on a normal day, and on this day, he's been drinking the same ooze that turned the turtles into humanoids.
This ooze supercharges Shredder's powers, and after the fight starts to not go his way, Shredder tries to off himself and the turtles by bringing the entire dock down on them. He's not exactly a good sport about losing, but in the end, Shredder only hurt himself.