149 total votes
Lepromatous leprosy

Lepromatous leprosy

Lepromatous leprosy is a skin condition consisting of pale macules. It results from the failure of Th1 cell activation which is necessary to eradicate the mycobacteria. In lepromatous leprosy, TH2 response is turned on, and because of reciprocal inhibition, the cell-mediated response is depressed. This debilitating form of leprosy begins to spread causing the eyebrows to disappear and spongy tumor like swellings appear on the face and body. The disease attacks the internal organs, bones, joints and marrow of the body resulting in physical degeneration. The result is deformity with loss of feeling in the fingers and toes which eventually fall off. This form of the disease is incurable ... more on Wikipedia

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